Knott, Graham

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

Trachtenberg, J. T., Chen, B. E., Knott, G. W., Feng, G., Sanes, J. R., Welker, E., & Svoboda, K. (2002) · Nature

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 1,927

Transient and persistent dendritic spines in the neocortex in vivo

Holtmaat, A. J. G. D., Trachtenberg, J. T., Wilbrecht, L., Shepherd, G. M., Zhang, X., Knott, G. W., & Svoboda, K. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 1,131

Mitonuclear protein imbalance as a conserved longevity mechanism

Houtkooper, R. H., Mouchiroud, L., Ryu, D., Moullan, N., Katsyuba, E., Knott, G., Williams, R. W., & Auwerx, J. (2013) · Nature

Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology

Cited by 1,035

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

Mahul-Mellier, A.-L., Burtscher, J., Maharjan, N., Weerens, L., Croisier, M., Kuttler, F., Leleu, M., Knott, G. W., & Lashuel, H. A. (2020) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 710

Serial section scanning electron microscopy of adult brain tissue using focused ion beam milling

Knott, G., Marchman, H., Wall, D., & Lich, B. (2008) · The Journal of Neuroscience

Advanced Electron Microscopy Techniques and ApplicationsAdvanced Materials Characterization Techniques

Cited by 692

Experience-dependent and cell-type-specific spine growth in the neocortex

Holtmaat, A., Wilbrecht, L., Knott, G. W., Welker, E., & Svoboda, K. (2006) · Nature

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 631

Experience and Activity-Dependent Maturation of Perisomatic GABAergic Innervation in Primary Visual Cortex during a Postnatal Critical Period

Chattopadhyaya, B., Di Cristo, G., Higashiyama, H., Knott, G. W., Kuhlman, S. J., Welker, E., & Huang, Z. J. (2004) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchVisual perception and processing mechanisms

Cited by 596

Synaptic proximity enables NMDAR signalling to promote brain metastasis

Zeng, Q., Michael, I. P., Zhang, P., Saghafinia, S., Knott, G., Jiao, W., McCabe, B. D., Galván, J. A., Robinson, H. P. C., Zlobec, I., et al. (2019) · Nature

Brain Metastases and TreatmentNeuroscience and Neuropharmacology Research

Cited by 574

Spine growth precedes synapse formation in the adult neocortex in vivo

Knott, G. W., Holtmaat, A., Wilbrecht, L., Welker, E., & Svoboda, K. (2006) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 563

Cell type-specific structural plasticity of axonal branches and boutons in the adult neocortex

De Paola, V., Holtmaat, A., Knott, G., Song, S., Wilbrecht, L., Caroni, P., & Svoboda, K. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 419

Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation

Korogod, N., Petersen, C. C., & Knott, G. W. (2015) · eLife

Neuroscience and Neuropharmacology ResearchAdvanced Electron Microscopy Techniques and Applications

Cited by 408

Rapid functional maturation of nascent dendritic spines

Zito, K., Scheuss, V., Knott, G., Hill, T., & Svoboda, K. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 272

The Relationship between PSD-95 Clustering and Spine Stability In Vivo

Cane, M., Maco, B., Knott, G., & Holtmaat, A. (2014) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 216

Altered synaptic dynamics during normal brain aging.

Mostany, R., Anstey, J. E., Crump, K. L., Maco, B., Knott, G., & Portera-Cailliau, C. (2013) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 179

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

D’Amico, D., Mottis, A., Potenza, F., Sorrentino, V., Li, H., Romani, M., Lemos, V., Schoonjans, K., Zamboni, N., Knott, G., et al. (2019) · Molecular Cell

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 159

Ultrastructurally smooth thick partitioning and volume stitching for large-scale connectomics

Hayworth, K. J., Xu, C. S., Lu, Z., Knott, G. W., Fetter, R. D., Tapia, J. C., Lichtman, J. W., & Hess, H. F. (2015) · Nature Methods

Advanced Electron Microscopy Techniques and ApplicationsAdvanced Materials Characterization Techniques

Cited by 144

In vivo modeling of human neuron dynamics and Down syndrome

Real, R., Peter, M., Trabalza, A., Khan, S., Smith, M. A., Dopp, J., Barnes, S. J., Momoh, A., Strano, A., Volpi, E., et al. (2018) · Science

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 120

Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties

Riguet, N., Mahul-Mellier, A.-L., Maharjan, N., Burtscher, J., Croisier, M., Knott, G., Hastings, J., Patin, A., Reiterer, V., Farhan, H., et al. (2021) · Nature Communications

Genetic Neurodegenerative DiseasesPrion Diseases and Protein Misfolding

Cited by 118

A protocol for preparing GFP-labeled neurons previously imaged in vivo and in slice preparations for light and electron microscopic analysis

Knott, G. W., Holtmaat, A., Trachtenberg, J. T., Svoboda, K., & Welker, E. (2009) · Nature Protocols

Neuroscience and Neuropharmacology ResearchAdvanced Fluorescence Microscopy Techniques

Cited by 76

Gas cluster ion beam SEM for imaging of large tissue samples with 10 nm isotropic resolution

Hayworth, K. J., Peale, D., Januszewski, M., Knott, G. W., Lu, Z., Xu, C. S., & Hess, H. F. (2020) · Nature Methods

Advanced Electron Microscopy Techniques and ApplicationsIon-surface interactions and analysis

Cited by 68