Frank, Matthew G.

Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation

Ledeboer, A., Sloane, E. M., Milligan, E. D., Frank, M. G., Mahony, J. H., Maier, S. F., & Watkins, L. R. (2005) · Pain

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 677

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

Kreisel, T., Frank, M. G., Licht, T., Reshef, R., Ben-Menachem-Zidon, O., Baratta, M. V., Maier, S. F., & Yirmiya, R. (2014) · Molecular Psychiatry

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 663

Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses

Frank, M. G., Baratta, M. V., Sprunger, D. B., Watkins, L. R., & Maier, S. F. (2007) · Brain Behavior and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 578

mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

Frank, M. G., Barrientos, R. M., Biedenkapp, J. C., Rudy, J. W., Watkins, L. R., & Maier, S. F. (2006) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 327

Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses

Frank, M. G., Thompson, B. M., Watkins, L. R., & Maier, S. F. (2012) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 310

Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide

Frank, M. G., Miguel, Z. D., Watkins, L. R., & Maier, S. F. (2010) · Brain, Behavior, and Immunity

Stress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms

Cited by 303

Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming

Frank, M. G., Weber, M. D., Watkins, L. R., & Maier, S. F. (2015) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsImmune Response and Inflammation

Cited by 237

Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats

Barrientos, R. M., Hein, A. M., Frank, M. G., Watkins, L. R., & Maier, S. F. (2012) · The Journal of Neuroscience

Anesthesia and Neurotoxicity ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 235

Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection

Barrientos, R. M., Frank, M. G., Hein, A. M., Higgins, E. A., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2009) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 226

Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders

Fleshner, M., Frank, M., & Maier, S. F. (2017) · Neuropsychopharmacology

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 216

Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome

Weber, M. D., Frank, M. G., Tracey, K. J., Watkins, L. R., & Maier, S. F. (2015) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 215

Stress-induced glucocorticoids as a neuroendocrine alarm signal of danger

Frank, M. G., Watkins, L. R., & Maier, S. F. (2013) · Brain, Behavior, and Immunity

Stress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms

Cited by 160

Little Exercise, Big Effects: Reversing Aging and Infection-Induced Memory Deficits, and Underlying Processes

Barrientos, R. M., Frank, M. G., Crysdale, N. Y., Chapman, T. R., Ahrendsen, J. T., Day, H. E. W., Campeau, S., Watkins, L. R., Patterson, S. L., & Maier, S. F. (2011) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 148

The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming

Fonken, L. K., Frank, M. G., Kitt, M. M., D'Angelo, H. M., Norden, D. M., Weber, M. D., Barrientos, R. M., Godbout, J. P., Watkins, L. R., & Maier, S. F. (2016) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAdvanced Glycation End Products research

Cited by 139

The redox state of the alarmin HMGB1 is a pivotal factor in neuroinflammatory and microglial priming: A role for the NLRP3 inflammasome

Frank, M. G., Weber, M. D., Fonken, L. K., Hershman, S. A., Watkins, L. R., & Maier, S. F. (2016) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsAdvanced Glycation End Products research

Cited by 133

Stress- and Glucocorticoid-Induced Priming of Neuroinflammatory Responses: Potential Mechanisms of Stress-Induced Vulnerability to Drugs of Abuse

Frank, M. G., Watkins, L. R., & Maier, S. F. (2011) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 116

Uncontrollable, But Not Controllable, Stress Desensitizes 5-HT1AReceptors in the Dorsal Raphe Nucleus

Rozeske, R. R., Evans, A. K., Frank, M. G., Watkins, L. R., Lowry, C. A., & Maier, S. F. (2011) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 100

Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge

Weber, M. D., Frank, M. G., Sobesky, J. L., Watkins, L. R., & Maier, S. F. (2013) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 93

Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia

Barrientos, R. M., Thompson, V. M., Kitt, M. M., Amat, J., Hale, M. W., Frank, M. G., Crysdale, N. Y., Stamper, C. E., Hennessey, P. A., Watkins, L. R., et al. (2015) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 70