Mallm, Jan-Philipp

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

Pfister, D., Núñez, N. G., Pinyol, R., Govaere, O., Pinter, M., Szydlowska, M., Gupta, R., Qiu, M., Deczkowska, A., Weiner, A., et al. (2021) · Nature

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 1,294

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

Solé-Boldo, L., Raddatz, G., Schütz, S., Mallm, J.-P., Rippe, K., Lonsdorf, A. S., Rodríguez-Paredes, M., & Lyko, F. (2020) · Communications Biology

Single-cell and spatial transcriptomicsSkin Protection and Aging

Cited by 559

Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH

Dudek, M., Pfister, D., Donakonda, S., Filpe, P., Schneider, A., Laschinger, M., Hartmann, D., Hüser, N., Meiser, P., Bayerl, F., et al. (2021) · Nature

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 518

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

Kalamakis, G., Brüne, D., Ravichandran, S., Bolz, J., Fan, W., Ziebell, F., Stiehl, T., Catalá-Martinez, F., Kupke, J., Zhao, S., et al. (2019) · Cell

Neurogenesis and neuroplasticity mechanismsMesenchymal stem cell research

Cited by 399

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

Brocks, D., Schmidt, C. R., Daskalakis, M., Jang, H. S., Shah, N. M., Li, D., Li, J., Zhang, B., Hou, Y., Laudato, S., et al. (2017) · Nature Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 339

Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging

Bogeska, R., Mikecin, A.-M., Kaschutnig, P., Fawaz, M., Büchler-Schäff, M., Le, D., Ganuza, M., Vollmer, A., Paffenholz, S. V., Asada, N., et al. (2022) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 299

Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues

Delacher, M., Imbusch, C. D., Weichenhan, D., Breiling, A., Hotz-Wagenblatt, A., Träger, U., Hofer, A.-C., Kägebein, D., Wang, Q., Frauhammer, F., et al. (2017) · Nature Immunology

T-cell and B-cell ImmunologyEpigenetics and DNA Methylation

Cited by 282

Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF

Delacher, M., Imbusch, C. D., Hotz-Wagenblatt, A., Mallm, J.-P., Bauer, K., Simon, M., Riegel, D., Rendeiro, A. F., Bittner, S., Sanderink, L., et al. (2020) · Immunity

T-cell and B-cell ImmunologyIL-33, ST2, and ILC Pathways

Cited by 261

HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types

Zirkel, A., Nikolic, M., Sofiadis, K., Mallm, J.-P., Brackley, C. A., Gothe, H., Drechsel, O., Becker, C., Altmüller, J., Josipovic, N., et al. (2018) · Molecular Cell

Genomics and Chromatin DynamicsTelomeres, Telomerase, and Senescence

Cited by 226

Haematopoietic stem cells in perisinusoidal niches are protected from ageing

Saçma, M., Pospiech, J., Bogeska, R., de Back, W., Mallm, J.-P., Sakk, V., Soller, K., Marka, G., Vollmer, A., Karns, R., et al. (2019) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 133

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis

Reich, M., Spomer, L., Klindt, C., Fuchs, K., Stindt, J., Deutschmann, K., Höhne, J., Liaskou, E., Hov, J. R., Karlsen, T. H., et al. (2021) · Journal of Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 121

Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

Jäger, N., Schlesner, M., Jones, D. T. W., Raffel, S., Mallm, J.-P., Junge, K. M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., et al. (2013) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 90

Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma

Lutz, R., Poos, A. M., Solé-Boldo, L., John, L., Wagner, J., Prokoph, N., Baertsch, M. A., Vonficht, D., Palit, S., Brobeil, A., et al. (2025) · Science Immunology

Multiple Myeloma Research and TreatmentsBone Tumor Diagnosis and Treatments

Cited by 25

Auto-Aggressive CXCR6(+) CD8 T Cells Cause Liver Immune Pathology in NASH

Dudek, M., Knolle, P., Pfister, D., Heikenwälder, M., Donakonda, S., Laschinger, M., Hartmann, D., Hüser, N., Sebode, M., Filpe, P., et al. (2022) · Zeitschrift für Gastroenterologie

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 18