Sander, Maike

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

Kopp, J. L., von Figura, G., Mayes, E., Liu, F.-F., Dubois, C. L., Morris, J. P., Pan, F. C., Akiyama, H., Wright, C. V. E., Jensen, K., et al. (2012) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Cells and Metastasis

Cited by 697

Inactivation of specific β cell transcription factors in type 2 diabetes

Guo, S., Dai, C., Guo, M., Taylor, B., Harmon, J. S., Sander, M., Robertson, R. P., Powers, A. C., & Stein, R. (2013) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 520

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

Font-Burgada, J., Shalapour, S., Ramaswamy, S., Hsueh, B., Rossell, D., Umemura, A., Taniguchi, K., Nakagawa, H., Valasek, M. A., Ye, L., et al. (2015) · Cell

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 486

Single cell chromatin accessibility reveals pancreatic islet cell type- and state-specific regulatory programs of diabetes risk

Chiou, J., Zeng, C., Cheng, Z., Han, J. Y., Schlichting, M., Huang, S., Wang, J., Sui, Y., Deogaygay, A., Okino, M.-L., et al. (2019) · Nature Genetics

Pancreatic function and diabetesGenomics and Chromatin Dynamics

Cited by 189

Stem cells versus plasticity in liver and pancreas regeneration

Kopp, J. L., Grompe, M., & Sander, M. (2016) · Nature Cell Biology

Liver physiology and pathologyPancreatic function and diabetes

Cited by 176

Lineage fate of ductular reactions in liver injury and carcinogenesis

Jörs, S., Jeliazkova, P., Ringelhan, M., Thalhammer, J., Dürl, S., Ferrer, J., Sander, M., Heikenwalder, M., Schmid, R. M., Siveke, J. T., et al. (2015) · Journal of Clinical Investigation

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 149

Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma

Lee, A. Y. L., Dubois, C. L., Sarai, K., Zarei, S., Schaeffer, D. F., Sander, M., & Kopp, J. L. (2019) · Gut

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 139

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel

Jin, L., Feng, T., Shih, H. P., Zerda, R., Luo, A., Hsu, J., Mahdavi, A., Sander, M., Tirrell, D. A., Riggs, A. D., et al. (2013) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 108

Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes

Zhu, H., Wang, G., Nguyen-Ngoc, K.-V., Kim, D., Miller, M., Goss, G., Kovsky, J., Harrington, A. R., Saunders, D., Melton, R., et al. (2022) · Developmental Cell

Pancreatic function and diabetesSingle-cell and spatial transcriptomics

Cited by 85

Loss of Pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice

Kopp, J. L., Dubois, C. L., Schaeffer, D. F., Samani, A., Taghizadeh, F., Cowan, R. W., Rhim, A. D., Stiles, B. L., Valasek, M., & Sander, M. (2018) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchPancreatic function and diabetes

Cited by 80

Differential Cell Susceptibilities to Kras in the Setting of Obstructive Chronic Pancreatitis

Shi, C., Pan, F. C., Kim, J. N., Washington, M. K., Padmanabhan, C., Meyer, C. T., Kopp, J. L., Sander, M., Gannon, M., Beauchamp, R. D., et al. (2019) · Cellular and Molecular Gastroenterology and Hepatology

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 21