Elemento, Olivier

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

Meyer, K. D., Saletore, Y., Zumbo, P., Elemento, O., Mason, C. E., & Jaffrey, S. R. (2012) · Cell

RNA modifications and cancerRNA regulation and disease

Cited by 4,223

Integrative Clinical Genomics of Advanced Prostate Cancer

Robinson, D., Van Allen, E. M., Wu, Y.-M., Schultz, N., Lonigro, R. J., Mosquera, J.-M., Montgomery, B., Taplin, M.-E., Pritchard, C. C., Attard, G., et al. (2015) · Cell

Prostate Cancer Treatment and ResearchCancer Genomics and Diagnostics

Cited by 3,645

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

Pritchard, C. C., Mateo, J., Walsh, M. F., De Sarkar, N., Abida, W., Beltran, H., Garofalo, A., Gulati, R., Carreira, S., Eeles, R., et al. (2016) · New England Journal of Medicine

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 1,680

Chromosomal instability drives metastasis through a cytosolic DNA response

Bakhoum, S. F., Ngo, B., Laughney, A. M., Cavallo, J.-A., Murphy, C. J., Ly, P., Shah, P., Sriram, R. K., Watkins, T. B. K., Taunk, N. K., et al. (2018) · Nature

interferon and immune responsesMicrotubule and mitosis dynamics

Cited by 1,593

The chromatin accessibility landscape of primary human cancers

Corces, M. R., Granja, J. M., Shams, S., Louie, B. H., Seoane, J. A., Zhou, W., Silva, T. C., Groeneveld, C., Wong, C. K., Cho, S. W., et al. (2018) · Science

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,230

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

Yun, J., Mullarky, E., Lu, C., Bosch, K. N., Kavalier, A., Rivera, K., Roper, J., Chio, I. I. C., Giannopoulou, E. G., Rago, C., et al. (2015) · Science

Vitamin C and Antioxidants ResearchCancer, Hypoxia, and Metabolism

Cited by 913

Artificial Intelligence in Cancer Research and Precision Medicine

Bhinder, B., Gilvary, C., Madhukar, N. S., & Elemento, O. (2021) · Cancer Discovery

AI in cancer detectionArtificial Intelligence in Healthcare and Education

Cited by 781

An atlas of substrate specificities for the human serine/threonine kinome

Johnson, J. L., Yaron, T. M., Huntsman, E. M., Kerelsky, A., Song, J., Regev, A., Lin, T.-Y., Liberatore, K., Cizin, D. M., Cohen, B. M., et al. (2023) · Nature

Advanced Proteomics Techniques and ApplicationsProtein Kinase Regulation and GTPase Signaling

Cited by 728

Deep learning-based classification of mesothelioma improves prediction of patient outcome

Courtiol, P., Maussion, C., Moarii, M., Pronier, E., Pilcer, S., Sefta, M., Manceron, P., Toldo, S., Zaslavskiy, M., Le Stang, N., et al. (2019) · Nature Medicine

AI in cancer detectionOccupational and environmental lung diseases

Cited by 544

Single-cell analysis of the muscle stem cell hierarchy identifies heterotypic communication signals involved in skeletal muscle regeneration

De Micheli, A. J., Laurilliard, E. J., Heinke, C. L., Ravichandran, H., Fraczek, P., Soueid-Baumgarten, S., De Vlaminck, I., Elemento, O., & Cosgrove, B. D. (2020) · Cell Reports

Muscle Physiology and DisordersSingle-cell and spatial transcriptomics

Cited by 373

Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial

Altorki, N. K., McGraw, T. E., Borczuk, A. C., Saxena, A., Port, J. L., Stiles, B. M., Lee, B. E., Sanfilippo, N. J., Scheff, R. J., Pua, B. B., et al. (2021) · The Lancet Oncology

Lung Cancer Diagnosis and TreatmentCancer Immunotherapy and Biomarkers

Cited by 342

Deep Convolutional Neural Networks Enable Discrimination of Heterogeneous Digital Pathology Images

Khosravi, P., Kazemi, E., Imielinski, M., Elemento, O., & Hajirasouliha, I. (2018) · EBioMedicine

AI in cancer detectionRadiomics and Machine Learning in Medical Imaging

Cited by 334

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

Qiao, Y., Giannopoulou, E. G., Chan, C. H., Park, S.-H., Gong, S., Chen, J., Hu, X., Elemento, O., & Ivashkiv, L. B. (2013) · Immunity

Immune Response and InflammationGenomics and Chromatin Dynamics

Cited by 330

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Li, J., Duran, M. A., Dhanota, N., Chatila, W. K., Bettigole, S. E., Kwon, J., Sriram, R. K., Humphries, M. P., Salto-Tellez, M., James, J. A., et al. (2021) · Cancer Discovery

Adenosine and Purinergic SignalingCancer Immunotherapy and Biomarkers

Cited by 312

A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials

Gayvert, K. M., Madhukar, N. S., & Elemento, O. (2016) · Cell chemical biology

Computational Drug Discovery MethodsPharmacovigilance and Adverse Drug Reactions

Cited by 310

Epigenetic memory of coronavirus infection in innate immune cells and their progenitors

Cheong, J.-G., Ravishankar, A., Sharma, S., Parkhurst, C. N., Grassmann, S. A., Wingert, C. K., Laurent, P., Ma, S., Paddock, L., Miranda, I. C., et al. (2023) · Cell

Immune responses and vaccinationsSARS-CoV-2 and COVID-19 Research

Cited by 309

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas

Jiang, Y., Ortega-Molina, A., Geng, H., Ying, H.-Y., Hatzi, K., Parsa, S., McNally, D., Wang, L., Doane, A. S., Agirre, X., et al. (2017) · Cancer Discovery

Lymphoma Diagnosis and TreatmentGenomics and Chromatin Dynamics

Cited by 278

Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system

Lhuillier, C., Rudqvist, N.-P., Elemento, O., Formenti, S. C., & Demaria, S. (2019) · Genome Medicine

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 276

Cell-Cycle Reprogramming for PI3K Inhibition Overrides a Relapse-Specific C481S BTK Mutation Revealed by Longitudinal Functional Genomics in Mantle Cell Lymphoma

Chiron, D., Di Liberto, M., Martin, P., Huang, X., Sharman, J., Blecua, P., Mathew, S., Vijay, P., Eng, K., Ali, S., et al. (2014) · Cancer Discovery

Lymphoma Diagnosis and TreatmentChronic Lymphocytic Leukemia Research

Cited by 273

Unmasking Activation of the Zygotic Genome Using Chromosomal Deletions in the Drosophila Embryo

De Renzis, S., Elemento, O., Tavazoie, S., & Wieschaus, E. F. (2007) · PLoS Biology

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 265

Artificial intelligence in cancer research, diagnosis and therapy

Elemento, O., Leslie, C., Lundin, J., & Tourassi, G. (2021) · Nature Reviews Cancer

AI in cancer detectionArtificial Intelligence in Healthcare and Education

Cited by 264

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

Palikuqi, B., Nguyen, D.-H. T., Li, G., Schreiner, R., Pellegata, A. F., Liu, Y., Redmond, D., Geng, F., Lin, Y., Gómez-Salinero, J. M., et al. (2020) · Nature

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 259

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis

Béguelin, W., Teater, M., Gearhart, M. D., Calvo Fernández, M. T., Goldstein, R. L., Cárdenas, M. G., Hatzi, K., Rosen, M., Shen, H., Corcoran, C. M., et al. (2016) · Cancer Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 254

Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer

Puca, L., Gavyert, K., Sailer, V., Conteduca, V., Dardenne, E., Sigouros, M., Isse, K., Kearney, M., Vosoughi, A., Fernandez, L., et al. (2019) · Science Translational Medicine

Prostate Cancer Treatment and ResearchLung Cancer Treatments and Mutations

Cited by 214