Busch, Dirk H.

NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ

Greten, F. R., Arkan, M. C., Bollrath, J., Hsu, L.-C., Goode, J., Miething, C., Göktuna, S. I., Neuenhahn, M., Fierer, J., Paxian, S., et al. (2007) · Cell

NF-κB Signaling PathwaysInflammasome and immune disorders

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A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

Enard, W., Gehre, S., Hammerschmidt, K., Hölter, S. M., Blass, T., Somel, M., Brückner, M. K., Schreiweis, C., Winter, C., Sohr, R., et al. (2009) · Cell

Genetics and Neurodevelopmental DisordersAnimal Vocal Communication and Behavior

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology

T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Cited by 531

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

Poeck, H., Besch, R., Maihoefer, C., Renn, M., Tormo, D., Morskaya, S. S., Kirschnek, S., Gaffal, E., Landsberg, J., Hellmuth, J., et al. (2008) · Nature Medicine

RNA Interference and Gene Deliveryinterferon and immune responses

Cited by 387

Rapamycin extends murine lifespan but has limited effects on aging

Neff, F., Flores-Dominguez, D., Ryan, D. P., Horsch, M., Schröder, S., Adler, T., Afonso, L. C., Aguilar-Pimentel, J. A., Becker, L., Garrett, L., et al. (2013) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 374

Serial Transfer of Single-Cell-Derived Immunocompetence Reveals Stemness of CD8+ Central Memory T Cells

Graef, P., Buchholz, V. R., Stemberger, C., Flossdorf, M., Henkel, L., Schiemann, M., Drexler, I., Höfer, T., Riddell, S. R., & Busch, D. H. (2014) · Immunity

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 311

Prevalence of sexual dimorphism in mammalian phenotypic traits

Karp, N. A., Mason, J., Beaudet, A. L., Benjamini, Y., Bower, L., Braun, R. E., Brown, S. D. M., Chesler, E. J., Dickinson, M. E., Flenniken, A. M., et al. (2017) · Nature Communications

Sex and Gender in HealthcareGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 257

Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function

Schober, K., Müller, T. R., Gökmen, F., Grassmann, S., Effenberger, M., Poltorak, M., Stemberger, C., Schumann, K., Roth, T. L., Marson, A., et al. (2019) · Nature Biomedical Engineering

CRISPR and Genetic EngineeringCAR-T cell therapy research

Cited by 178

Dual-Track Clearance of Circulating Bacteria Balances Rapid Restoration of Blood Sterility with Induction of Adaptive Immunity

Broadley, S. P., Plaumann, A., Coletti, R., Lehmann, C., Wanisch, A., Seidlmeier, A., Esser, K., Luo, S., Rämer, P. C., Massberg, S., et al. (2016) · Cell Host & Microbe

Complement system in diseasesImmune Response and Inflammation

Cited by 156

CD40L expression permits CD8+ T cells to execute immunologic helper functions

Frentsch, M., Stark, R., Matzmohr, N., Meier, S., Durlanik, S., Schulz, A. R., Stervbo, U., Jürchott, K., Gebhardt, F., Heine, G., et al. (2013) · Blood

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 100

Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases

Saggau, C., Bacher, P., Esser, D., Rasa, M., Meise, S., Mohr, N., Kohlstedt, N., Hutloff, A., Schacht, S.-S., Dargvainiene, J., et al. (2024) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 79

Additive manufacturing of scaffolds with dexamethasone controlled release for enhanced bone regeneration

Costa, P. F., Puga, A. M., Díaz-Gomez, L., Concheiro, A., Busch, D. H., & Alvarez-Lorenzo, C. (2015) · International Journal of Pharmaceutics

Bone Tissue Engineering Materials3D Printing in Biomedical Research

Cited by 78

A novel N‐ethyl‐N‐nitrosourea–induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

Abe, K., Fuchs, H., Boersma, A., Hans, W., Yu, P., Kalaydjiev, S., Klaften, M., Adler, T., Calzada‐Wack, J., Mossbrugger, I., et al. (2011) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesSystemic Lupus Erythematosus Research

Cited by 46

Cutting Edge: Memory CD8 T Cell Compartment Grows in Size with Immunological Experience but Nevertheless Can Lose Function

Huster, K. M., Stemberger, C., Gasteiger, G., Kastenmüller, W., Drexler, I., & Busch, D. H. (2009) · The Journal of Immunology

T-cell and B-cell ImmunologyImmune responses and vaccinations

Cited by 37

Predicting T Cell Receptor Functionality against Mutant Epitopes

Dorigatti, E., Drost, F., Straub, A., Hilgendorf, P., Wagner, K. I., Bischl, B., Busch, D. H., Schober, K., & Schubert, B. (2023) · Cell Genomics

vaccines and immunoinformatics approachesImmunotherapy and Immune Responses

Cited by 30

Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair

Moosmann, C., Müller, T. R., Busch, D. H., & Schober, K. (2022) · STAR Protocols

CRISPR and Genetic EngineeringCAR-T cell therapy research

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CIP2A promotes T-cell activation and immune response to Listeria monocytogenes infection

Côme, C., Cvrljevic, A., Khan, M. M., Treise, I., Adler, T., Aguilar-Pimentel, J. A., Au-Yeung, B., Sittig, E., Laajala, T. D., Chen, Y., et al. (2016) · PLoS ONE

T-cell and B-cell ImmunologySignaling Pathways in Disease

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