Newgard, Christopher B.

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Softic, S., Meyer, J. G., Wang, G.-X., Gupta, M. K., Batista, T. M., Lauritzen, H. P. M. M., Fujisaka, S., Serra, D., Herrero, L., Willoughby, J., et al. (2019) · Cell Metabolism

Diet, Metabolism, and DiseaseMetabolism, Diabetes, and Cancer

Cited by 227

Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1.

Newgard, C. B., Brady, M. J., O'Doherty, R. M., & Saltiel, A. R. (2000) · Diabetes

Glycogen Storage Diseases and MyoclonusMetabolism, Diabetes, and Cancer

Cited by 189

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells

Ferdaoussi, M., Dai, X., Jensen, M. V., Wang, R., Peterson, B. S., Huang, C., Ilkayeva, O., Smith, N., Miller, N., Hajmrle, C., et al. (2015) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 169

Prior dietary practices and connections to a human gut microbial metacommunity alter responses to diet interventions

Griffin, N. W., Ahern, P. P., Cheng, J., Heath, A. C., Ilkayeva, O., Newgard, C. B., Fontana, L., & Gordon, J. I. (2017) · Cell Host & Microbe

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 164

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77

Chao, L. C., Wroblewski, K., Zhang, Z., Pei, L., Vergnes, L., Ilkayeva, O. R., Ding, S. Y., Reue, K., Watt, M. J., Newgard, C. B., et al. (2009) · Diabetes

Nuclear Receptors and SignalingMetabolism, Diabetes, and Cancer

Cited by 154

Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α

Yoon, J. C., Xu, G., Deeney, J. T., Yang, S.-N., Rhee, J., Puigserver, P., Levens, A. R., Yang, R., Zhang, C.-Y., Lowell, B. B., et al. (2003) · Developmental Cell

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 143

Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue

Boucher, A., Lu, D., Burgess, S. C., Telemaque-Potts, S., Jensen, M. V., Mulder, H., Wang, M.-Y., Unger, R. H., Sherry, A. D., & Newgard, C. B. (2004) · Journal of Biological Chemistry

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 136

A deep catalogue of protein-coding variation in 983,578 individuals

Sun, K. Y., Bai, X., Chen, S., Bao, S., Zhang, C., Kapoor, M., Backman, J., Joseph, T., Maxwell, E., Mitra, G., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 127

Overexpression of Rat Long Chain Acyl-CoA Synthetase 1 Alters Fatty Acid Metabolism in Rat Primary Hepatocytes

Li, L. O., Mashek, D. G., An, J., Doughman, S. D., Newgard, C. B., & Coleman, R. A. (2006) · Journal of Biological Chemistry

Lipid metabolism and biosynthesisCancer, Lipids, and Metabolism

Cited by 123

The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain

Lien, L. F., Haqq, A. M., Arlotto, M., Slentz, C. A., Muehlbauer, M. J., McMahon, R. L., Rochon, J., Gallup, D., Bain, J. R., Ilkayeva, O., et al. (2009) · OMICS: A Journal of Integrative Biology

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 97

Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL

Civitarese, A. E., MacLean, P. S., Carling, S., Kerr-Bayles, L., McMillan, R. P., Pierce, A., Becker, T. C., Moro, C., Finlayson, J., Lefort, N., et al. (2010) · Cell Metabolism

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 95

Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue

Samms, R. J., Zhang, G., He, W., Ilkayeva, O., Droz, B. A., Bauer, S. M., Stutsman, C., Pirro, V., Collins, K. A., Furber, E. C., et al. (2022) · Molecular Metabolism

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 93

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.

Scholtens, D. M., Bain, J. R., Reisetter, A. C., Muehlbauer, M. J., Nodzenski, M., Stevens, R. D., Ilkayeva, O., Lowe, L. P., Metzger, B. E., Newgard, C. B., et al. (2016) · Diabetes

Gestational Diabetes Research and ManagementMetabolomics and Mass Spectrometry Studies

Cited by 69

Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity

Huffman, K. M., Slentz, C. A., Bateman, L. A., Thompson, D., Muehlbauer, M. J., Bain, J. R., Stevens, R. D., Wenner, B. R., Kraus, V. B., Newgard, C. B., et al. (2011) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 66