Morris, John C.

Loss of white matter integrity reflects tau accumulation in Alzheimer disease defined regions

Strain, J. F., Smith, R. X., Beaumont, H., Roe, C. M., Gordon, B. A., Mishra, S., Adeyemo, B., Christensen, J. J., Su, Y., Morris, J. C., et al. (2018) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 97

Genetic Heterogeneity in Alzheimer Disease and Implications for Treatment Strategies

Dominantly Inherited Alzheimer Network, Ringman, J. M., Goate, A., Masters, C. L., Cairns, N. J., Danek, A., Graff-Radford, N., Ghetti, B., & Morris, J. C. (2014) · Current Neurology and Neuroscience Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 96

GPS driving: a digital biomarker for preclinical Alzheimer disease

Bayat, S., Babulal, G. M., Schindler, S. E., Fagan, A. M., Morris, J. C., Mihailidis, A., & Roe, C. M. (2021) · Alzheimer's Research & Therapy

Older Adults Driving StudiesDementia and Cognitive Impairment Research

Cited by 91

The informed road map to prevention of Alzheimer Disease: a call to arms

McDade, E., Llibre-Guerra, J. J., Holtzman, D. M., Morris, J. C., & Bateman, R. J. (2021) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 89

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 88

Neuropathologic assessment of participants in two multi‐center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN)

Cairns, N. J., Perrin, R. J., Franklin, E. E., Carter, D., Vincent, B., Xie, M., Bateman, R. J., Benzinger, T., Friedrichsen, K., Brooks, W. S., et al. (2015) · Neuropathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 86

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

Li, Z., Farias, F. H. G., Dube, U., Del-Aguila, J. L., Mihindukulasuriya, K. A., Fernandez, M. V., Ibanez, L., Budde, J. P., Wang, F., Lake, A. M., et al. (2020) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 85

Extreme cerebrospinal fluid amyloid β levels identify family with late‐onset Alzheimer's disease presenilin 1 mutation

Kauwe, J. S. K., Jacquart, S., Chakraverty, S., Wang, J., Mayo, K., Fagan, A. M., Holtzman, D. M., Morris, J. C., & Goate, A. M. (2007) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 84

Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease

Sung, Y. J., Yang, C., Norton, J., Johnson, M., Fagan, A., Bateman, R. J., Perrin, R. J., Morris, J. C., Farlow, M. R., Chhatwal, J. P., et al. (2023) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 84

Addressing Health Disparities Among Minority Populations: Why Clinical Trial Recruitment Is Not Enough

Wilkins, C. H., Schindler, S. E., & Morris, J. C. (2020) · JAMA Neurology

Health disparities and outcomesCultural Competency in Health Care

Cited by 83

Phosphorylated Tau-Aβ42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid

Harari, O., Cruchaga, C., Kauwe, J. S. K., Ainscough, B. J., Bales, K., Pickering, E. H., Bertelsen, S., Fagan, A. M., Holtzman, D. M., Morris, J. C., et al. (2014) · Biological Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 82

Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta

Kauwe, J. S. K., Wang, J., Mayo, K., Morris, J. C., Fagan, A. M., Holtzman, D. M., & Goate, A. M. (2009) · neurogenetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 82

Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease

Young, C. B., Winer, J. R., Younes, K., Cody, K. A., Betthauser, T. J., Johnson, S. C., Schultz, A., Sperling, R. A., Greicius, M. D., Cobos, I., et al. (2022) · JAMA Neurology

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Cited by 79

BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

Lim, Y. Y., Hassenstab, J., Cruchaga, C., Goate, A., Fagan, A. M., Benzinger, T. L. S., Maruff, P., Snyder, P. J., Masters, C. L., Allegri, R., et al. (2016) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 76

Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

Chen, S.-D., Lu, J.-Y., Li, H.-Q., Yang, Y.-X., Jiang, J.-H., Cui, M., Zuo, C.-T., Tan, L., Dong, Q., Yu, J.-T., et al. (2021) · Translational Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 71

Neuropsychological changes in asymptomatic persons with Alzheimer disease neuropathology

Monsell, S. E., Mock, C., Hassenstab, J., Roe, C. M., Cairns, N. J., Morris, J. C., & Kukull, W. (2014) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 71

Will anti-amyloid therapies work for Alzheimer's disease?

St George-Hyslop, P. H., & Morris, J. C. (2008) · The Lancet

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 69

Comparative analysis of Alzheimer's disease cerebrospinal fluid biomarkers measurement by multiplex SOMAscan platform and immunoassay‐based approach

Timsina, J., Gomez-Fonseca, D., Wang, L., Do, A., Western, D., Alvarez, I., Aguilar, M., Pastor, P., Henson, R. L., Herries, E., et al. (2022) · Journal of Alzheimer’s Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 68

Neuropathologic criteria for diagnosing Alzheimer Disease in persons with pure dementia of Alzheimer type

McKeel, D. W., Price, J. L., Miller, J. P., Grant, E. A., Xiong, C., Berg, L., & Morris, J. C. (2004) · Journal of Neuropathology & Experimental Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 68

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

for the Dominantly Inherited Alzheimer Network (DIAN), Twohig, D., Rodriguez-Vieitez, E., Sando, S. B., Berge, G., Lauridsen, C., Møller, I., Grøntvedt, G. R., Bråthen, G., Patra, K., et al. (2018) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 68

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology

Morris, J. C., Weiner, M., Xiong, C., Beckett, L., Coble, D., Saito, N., Aisen, P. S., Allegri, R., Benzinger, T. L. S., Berman, S. B., et al. (2022) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 68

A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin

Deming, Y., Xia, J., Cai, Y., Lord, J., Holmans, P., Bertelsen, S., Holtzman, D., Morris, J. C., Bales, K., Pickering, E. H., et al. (2016) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 66

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease

Eteleeb, A. M., Novotny, B. C., Tarraga, C. S., Sohn, C., Dhungel, E., Brase, L., Nallapu, A., Buss, J., Farias, F., Bergmann, K., et al. (2024) · PLOS Biology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 64

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease

Wang, Q., Wang, Y., Liu, J., Sutphen, C. L., Cruchaga, C., Blazey, T., Gordon, B. A., Su, Y., Chen, C., Shimony, J. S., et al. (2019) · NeuroImage: Clinical

Advanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment Research

Cited by 63