Deeks, Steven G.

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., et al. (2006) · Nature Medicine

HIV Research and TreatmentHIV-related health complications and treatments

Cited by 3,559

HIV Infection, Inflammation, Immunosenescence, and Aging

Deeks, S. G. (2011) · Annual Review of Medicine

HIV Research and TreatmentHIV-related health complications and treatments

Cited by 1,349

. Plasma levels of soluble CD14 independently predict mortality in HIV infection.

Sandler, N. G., Wand, H., Roque, A., Law, M., Nason, M. C., Nixon, D. E., Pedersen, C., Ruxrungtham, K., Lewin, S. R., Emery, S., et al. (2011) · The Journal of Infectious Diseases

HIV Research and TreatmentHIV-related health complications and treatments

Cited by 1,106

Defective proviruses rapidly accumulate during acute HIV-1 infection

Bruner, K. M., Murray, A. J., Pollack, R. A., Soliman, M. G., Laskey, S. B., Capoferri, A. A., Lai, J., Strain, M. C., Lada, S. M., Hoh, R., et al. (2016) · Nature Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 737

A quantitative approach for measuring the reservoir of latent HIV-1 proviruses

Bruner, K. M., Wang, Z., Simonetti, F. R., Bender, A. M., Kwon, K. J., Sengupta, S., Fray, E. J., Beg, S. A., Antar, A. A. R., Jenike, K. M., et al. (2019) · Nature

HIV Research and TreatmentVirus-based gene therapy research

Cited by 718

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality

Serrano-Villar, S., Sainz, T., Lee, S. A., Hunt, P. W., Sinclair, E., Shacklett, B. L., Ferre, A. L., Hayes, T. L., Somsouk, M., Hsue, P. Y., et al. (2014) · PLoS Pathogens

HIV Research and TreatmentHIV-related health complications and treatments

Cited by 611

HIV and Aging: State of Knowledge and Areas of Critical Need for Research. A Report to the NIH Office of AIDS Research by the HIV and Aging Working Group

High, K. P., Brennan-Ing, M., Clifford, D. B., Cohen, M. H., Currier, J., Deeks, S. G., Deren, S., Effros, R. B., Gebo, K., Goronzy, J. J., et al. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes

HIV-related health complications and treatmentsHIV Research and Treatment

Cited by 522

Identification of genetically intact HIV-1 proviruses in specific CD4 + T cells from effectively treated participants

Hiener, B., Horsburgh, B. A., Eden, J.-S., Barton, K., Schlub, T. E., Lee, E., von Stockenstrom, S., Odevall, L., Milush, J. M., Liegler, T., et al. (2017) · Cell Reports

HIV Research and TreatmentVirus-based gene therapy research

Cited by 370

TIGIT marks exhausted T cells, correlates with disease progression, and serves as a target for immune restoration in HIV and SIV infection

Chew, G. M., Fujita, T., Webb, G. M., Burwitz, B. J., Wu, H. L., Reed, J. S., Hammond, K. B., Clayton, K. L., Ishii, N., Abdel-Mohsen, M., et al. (2016) · PLoS Pathogens

HIV Research and TreatmentT-cell and B-cell Immunology

Cited by 323

Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection

Sandler, N. G., Koh, C., Roque, A., Eccleston, J. L., Siegel, R. B., Demino, M., Kleiner, D. E., Deeks, S. G., Liang, T. J., Heller, T., et al. (2011) · Gastroenterology

Liver Disease and TransplantationHepatitis C virus research

Cited by 307

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study

Elliott, J. H., McMahon, J. H., Chang, C. C., Lee, S. A., Hartogensis, W., Bumpus, N., Savic, R., Roney, J., Hoh, R., Solomon, A., et al. (2015) · The Lancet HIV

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 250

Short-Term Effects of Cannabinoids in Patients with HIV-1 Infection: A Randomized, Placebo-Controlled Clinical Trial

Abrams, D. I., Hilton, J. F., Leiser, R. J., Shade, S. B., Elbeik, T. A., Aweeka, F. T., Benowitz, N. L., Bredt, B. M., Kosel, B., Aberg, J. A., et al. (2003) · Annals of Internal Medicine

Cannabis and Cannabinoid ResearchHIV/AIDS drug development and treatment

Cited by 238

SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay

Peluso, M. J., Takahashi, S., Hakim, J., Kelly, J. D., Torres, L., Iyer, N. S., Turcios, K., Janson, O., Munter, S. E., Thanh, C., et al. (2021) · Science Advances

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing

Cited by 130

Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes

Abdelsamed, H. A., Zebley, C. C., Nguyen, H., Rutishauser, R. L., Fan, Y., Ghoneim, H. E., Crawford, J. C., Alfei, F., Alli, S., Ribeiro, S. P., et al. (2020) · Nature Immunology

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 121

A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5

Tilton, J. C., Wilen, C. B., Didigu, C. A., Sinha, R., Harrison, J. E., Agrawal-Gamse, C., Henning, E. A., Bushman, F. D., Martin, J. N., Deeks, S. G., et al. (2010) · Journal of Virology

HIV/AIDS drug development and treatmentHIV Research and Treatment

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Expression profile of host restriction factors in HIV-1 elite controllers

Abdel-Mohsen, M., Raposo, R. A. S., Deng, X., Li, M., Liegler, T., Sinclair, E., Salama, M. S., Ghanem, H. E.-D. A., Hoh, R., Wong, J. K., et al. (2013) · Retrovirology

HIV Research and Treatmentinterferon and immune responses

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A randomized, controlled trial of mindfulness-based stress reduction in HIV infection

Hecht, F. M., Moskowitz, J. T., Moran, P., Epel, E. S., Bacchetti, P., Acree, M., Kemeny, M. E., Mendes, W. B., Duncan, L. G., Weng, H., et al. (2018) · Brain Behavior and Immunity

Mindfulness and Compassion InterventionsHIV/AIDS Research and Interventions

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Efficient mRNA delivery to resting T cells to reverse HIV latency

Cevaal, P. M., Kan, S., Fisher, B. M., Moso, M. A., Tan, A., Liu, H., Ali, A., Tanaka, K., Shepherd, R. A., Kim, Y., et al. (2025) · Nature Communications

RNA Interference and Gene DeliveryHIV Research and Treatment

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Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans

Seu, L., Burt, T. D., Witte, J. S., Martin, J. N., Deeks, S. G., & McCune, J. M. (2012) · Genes & Immunity

Heme Oxygenase-1 and Carbon MonoxideHIV Research and Treatment

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Target product profile for cell-based and gene-based therapies to achieve a cure for HIV

Lewin, S. R., Bansbach, C., Kemps, D., Mathae, L., Das, K. T., McCune, J. M., Deeks, S. G., & Ndung'u, T. (2025) · The Lancet HIV

HIV Research and TreatmentVirus-based gene therapy research

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Activating PKC-ε induces HIV expression with improved tolerability

Irrinki, A. M., Kaur, J., Randhawa, B., McFadden, R., Snyder, C., Truong, H., Soohoo, D., Hu, E., Yu, H., Murray, B. P., et al. (2025) · PLOS Pathogens

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 5