. Plasma levels of soluble CD14 independently predict mortality in HIV infection.

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Brenchley, J. M., Price, D. A., Schacker, T. W., Asher, T. E., Silvestri, G., Rao, S., Kazzaz, Z., Bornstein, E., Lambotte, O., Altmann, D., et al. (2006) · Nature Medicine · doi:10.1038/nm1511 · Cited by 3,559 · see citing works

CD4+ Count–Guided Interruption of Antiretroviral Treatment

The Strategies for Management of Antiretroviral Therapy (SMART) Study Group (2006) · New England Journal of Medicine · doi:10.1056/nejmoa062360 · Cited by 2,230 · see citing works

CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract

Brenchley, J. M., Schacker, T. W., Ruff, L. E., Price, D. A., Taylor, J. H., Beilman, G. J., Nguyen, P. L., Khoruts, A., Larson, M. C., Haase, A. T., et al. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20040874 · Cited by 1,836 · see citing works

. Inflammatory and coagulation biomarkers and mortality in patients with HIV infection.

Kuller, L. H., Tracy, R., Belloso, W., Wit, S. D., Drummond, F., Lane, H. C., Ledergerber, B., Lundgren, J., Neuhaus, J., Nixon, D., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050203 · Cited by 1,617 · see citing works

Gastrointestinal Tract as a Major Site of CD4 + T Cell Depletion and Viral Replication in SIV Infection

Veazey, R. S., DeMaria, M. A., Chalifoux, L. V., Shvetz, D. E., Pauley, D. R., Knight, H., Rosenzweig, M., Johnson, R. P., Desrosiers, R. C., & Lackner, A. A. (1998) · Science · doi:10.1126/science.280.5362.427 · Cited by 1,404 · see citing works

LPS, TLR4 and infectious disease diversity

Miller, S., Ernst, R. K., & Bader, M. W. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1068 · Cited by 1,059 · see citing works

Shorter Survival in Advanced Human Immunodeficiency Virus Type 1 Infection Is More Closely Associated with T Lymphocyte Activation than with Plasma Virus Burden or Virus Chemokine Coreceptor Usage

Giorgi, J. V., Hultin, L. E., McKeating, J. A., Johnson, T. D., Owens, B. M., Jacobson, L. P., Shih, R., Lewis, J., Wiley, D. J., Phair, J. P., et al. (1999) · The Journal of Infectious Diseases · doi:10.1086/314660 · Cited by 1,032 · see citing works

T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

Hunt, P. W., Martin, J. N., Sinclair, E., Bredt, B. M., Hagos, E., Lampiris, H. W., & Deeks, S. G. (2003) · The Journal of Infectious Diseases · doi:10.1086/374786 · Cited by 852 · see citing works

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

Deeks, S. G., Ramirez, C. M., Liu, L., Guo, H., Gascon, R., Narváez, A. B., Hunt, P. W., Martin, J. N., Kahn, J. S., Levy, J. A., et al. (2004) · Blood · doi:10.1182/blood-2003-09-3333 · Cited by 803 · see citing works

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

Hellerstein, M. K., Hanley, M. B., Cesar, D., Siler, S., Papageorgopoulos, C., Wieder, E., Schmidt, D. J., Hoh, R., Neese, R. A., Macallan, D. C., et al. (1999) · Nature Medicine · doi:10.1038/4772 · Cited by 592 · see citing works

Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral‐Treated HIV Infection

Jiang, W., Lederman, M. M., Hunt, P. W., Sieg, S. F., Haley, K. P., Rodriguez, B. A., LANDAY, A. L., Martin, J. N., Sinclair, E., Asher, A. I., et al. (2009) · The Journal of Infectious Diseases · doi:10.1086/597476 · Cited by 591 · see citing works

Enteropathy Associated with the Acquired Immunodeficiency Syndrome

Kotler, D. P., GAETZ, H. P., LANGE, M., KLEIN, E. B., & HOLT, P. R. (1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-101-4-421 · Cited by 590 · see citing works

HIV disease: fallout from a mucosal catastrophe?

Brenchley, J. M., Price, D. A., & Douek, D. C. (2006) · Nature Immunology · doi:10.1038/ni1316 · Cited by 579 · see citing works

Elevated CD38 Antigen Expression on CD8+ T Cells Is a Stronger Marker for the Risk of Chronic HIV Disease Progression to AIDS and Death in the Multicenter AIDS Cohort Study Than CD4+ Cell Count, Soluble Immune Activation Markers, or Combinations of HLA-DR and CD38 Expression

Liu, Z., Cumberland, W. G., Hultin, L. E., Prince, H. E., Detels, R., & Giorgi, J. V. (1997) · Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology · doi:10.1097/00042560-199710010-00003 · Cited by 547 · see citing works

T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)

Hazenberg, M. D., Stuart, J. W. T. C., Otto, S. A., Borleffs, J. C. C., Boucher, C. A., de Boer, R. J., Miedema, F. F., & Hamann, D. (2000) · Blood · doi:10.1182/blood.v95.1.249 · Cited by 451 · see citing works

Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility

Pelsers, M. M. A. L., Namiot, Z., Kisielewski, W., Namiot, A., Januszkiewicz, M., Hermens, W. T., & Glatz, J. F. C. (2003) · Clinical Biochemistry · doi:10.1016/s0009-9120(03)00096-1 · Cited by 377 · see citing works

Initial responses to endotoxins and Gram-negative bacteria

Heumann, D., & Roger, T. (2002) · Clinica Chimica Acta · doi:10.1016/s0009-8981(02)00180-8 · Cited by 359 · see citing works

Predictive Value of Plasma HIV RNA Level on Rate of CD4 T-Cell Decline in Untreated HIV Infection

Rodriguez, B. A., Sethi, A. K., Cheruvu, V. K., Mackay, W., Bosch, R. J., Kitahata, M. M., Boswell, S., Mathews, W. C., Bangsberg, D. R., Martin, J. N., et al. (2006) · JAMA · doi:10.1001/jama.296.12.1498 · Cited by 318 · see citing works

Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy

Marchetti, G. C., Bellistrì, G. M., Borghi, E., Tincati, C., Ferramosca, S., Francesca, M. L., Morace, G., Gori, A., & Monforte, A. D. (2008) · AIDS · doi:10.1097/qad.0b013e3283112d29 · Cited by 296 · see citing works

DNA isolation by a rapid method from human blood samples: Effects of MgCl2, EDTA, storage time, and temperature on DNA yield and quality

Lahiri, D. K., & Schnabel, B. (1993) · Biochemical Genetics · doi:10.1007/bf02401826 · Cited by 259 · see citing works

Interruption of Antiretroviral Therapy and Risk of Cardiovascular Disease in Persons with HIV-1 Infection: Exploratory Analyses from the SMART Trial

Phillips, A. N., Carr, A. D., Neuhaus, J., Visnegarwala, F., Prineas, R. J., Burman, W. J., Williams, I. G., Drummond, F., Duprez, D. A., Belloso, W. H., et al. (2008) · Antiviral Therapy · doi:10.1177/135965350801300215 · Cited by 240 · see citing works

Human monocyte CD14 is upregulated by lipopolysaccharide

Landmann, R., Knopf, H. P., Link, S., Sansano, S., Schumann, R., & Zimmerli, W. (1996) · Infection and Immunity · doi:10.1128/iai.64.5.1762-1769.1996 · Cited by 234 · see citing works

DNA isolation by a rapid method from human blood samples: Effects of MgCl2, EDTA, storage time, and temperature on DNA yield and quality

Lahiri, D. K., & Schnabel, B. (1993) · Biochemical Genetics · doi:10.1007/bf00553174 · Cited by 201 · see citing works

Plasma CD14 decreases monocyte responses to LPS by transferring cell-bound LPS to plasma lipoproteins

Kitchens, R. L., Thompson, P. A., Viriyakosol, S., O’Keefe, G. E., & Munford, R. S. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13139 · Cited by 199 · see citing works

Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14

Hailman, E., Vasselon, T., Kelley, M. A., Busse, L. A., Hu, M. C. ‐., Lichenstein, H. S., Detmers, P. A., & Wright, S. D. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.156.11.4384 · Cited by 197 · see citing works

Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells

Gioannini, T. L., & Weiss, J. P. (2007) · Immunologic Research · doi:10.1007/s12026-007-0069-0 · Cited by 195 · see citing works

Plasma CD14 decreases monocyte responses to LPS by transferring cell-bound LPS to plasma lipoproteins

Kitchens, R. L., Thompson, P. A., Viriyakosol, S., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200113139 · Cited by 172 · see citing works

Activation and Coagulation Biomarkers Are Independent Predictors of the Development of Opportunistic Disease in Patients with HIV Infection

Rodger, A. J., Fox, Z. V., Lundgren, J. D., Kuller, L. H., Boesecke, C., Gey, D., Skoutelis, A., Goetz, M. B., Phillips, A. N., & the INSIGHT Strategies for Management of Antiretroviral Therapy (SMART) Study Group (2009) · The Journal of Infectious Diseases · doi:10.1086/605447 · Cited by 160 · see citing works

Roles for accessory molecules in microbial recognition by Toll-like receptors

Miyake, K. (2006) · Journal of Endotoxin Research · doi:10.1179/096805106x118807 · Cited by 150 · see citing works

Microbial translocation induces persistent macrophage activation unrelated to HIV-1 levels or T-cell activation following therapy

Wallet, M. A., Rodriguez, C. A., Yin, L., Saporta, S., Chinratanapisit, S., Hou, W., Sleasman, J. W., & Goodenow, M. M. (2010) · AIDS · doi:10.1097/qad.0b013e328339e228 · Cited by 149 · see citing works

Simian Immunodeficiency Virus–Induced Intestinal Cell Apoptosis Is the Underlying Mechanism of the Regenerative Enteropathy of Early Infection

Li, Q., Estes, J. D., Duan, L., Jessurun, J., Pambuccian, S. E., Forster, C. L., Wietgrefe, S. W., Zupancic, M., Schacker, T. W., Reilly, C., et al. (2008) · The Journal of Infectious Diseases · doi:10.1086/525046 · Cited by 131 · see citing works

Cytokines and cytokine therapies in HIV infection.

Valdez, H., & Lederman, M. M. (1997) · PubMed · Cited by 127 · see citing works

Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans

Talwar, S., Munson, P. J., Barb, J. J., Fiuza, C., Cintron, A. D. P., Logun, C., Tropea, M., Khan, S. S., Reda, D., Shelhamer, J. H., et al. (2006) · Physiological Genomics · doi:10.1152/physiolgenomics.00192.2005 · Cited by 127 · see citing works

Biological Determinants of Immune Reconstitution in HIV‐Infected Patients Receiving Antiretroviral Therapy: The Role of Interleukin 7 and Interleukin 7 Receptor α and Microbial Translocation

Rajasuriar, R., Booth, D. R., Solomon, A. E., Chua, K., Spelman, T. D., Gouillou, M., Schlub, T. E., Davenport, M. P., Crowe, S. M., Elliott, J., et al. (2010) · The Journal of Infectious Diseases · doi:10.1086/656369 · Cited by 115 · see citing works

Lipoprotein particle subclasses, cardiovascular disease and HIV infection

Duprez, D. A., Kuller, L. H., Tracy, R. P., Otvos, J. D., Cooper, D. A., Hoy, J., Neuhaus, J., Paton, N. I., Friis‐Møller, N., Lampe, F. C., et al. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.05.001 · Cited by 111 · see citing works

Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit*

Henckaerts, L., Nielsen, K. R., Steffensen, R., Steen, K. V., Mathieu, C., Giulietti, A., Wouters, P. J., Milants, I., Vanhorebeek, I., Langouche, L., et al. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31819263d8 · Cited by 103 · see citing works

The immune response to AIDS virus infection: good, bad, or both?

Deeks, S. G., & Walker, B. D. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21318 · Cited by 69 · see citing works

Endotoxin Binding and Elimination by Monocytes: Secretion of Soluble CD14 Represents an Inducible Mechanism Counteracting Reduced Expression of Membrane CD14 in Patients with Sepsis and in a Patient with Paroxysmal Nocturnal Hemoglobinuria

Hiki, N., Berger, D., Prigl, C., Boelke, E., Wiedeck, H., Seidelmann, M., Staib, L., Kaminishi, M., Oohara, T., & Beger, H. G. (1998) · Infection and Immunity · doi:10.1128/iai.66.3.1135-1141.1998 · Cited by 63 · see citing works

Immunopathogenesis of asymptomatic chronic HIV Infection: the calm before the storm

Ford, E. S., Puronen, C. E., & Sereti, I. (2009) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0b013e328329c68c · Cited by 63 · see citing works

The immune response to AIDS virus infection: good, bad, or both?

Deeks, S. G., & Walker, B. D. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200421318 · Cited by 63 · see citing works

Association of Soluble Endotoxin Receptor CD14 and Mortality Among Patients Undergoing Hemodialysis

Raj, D. S., Shah, V. O., Rambod, M., Kovesdy, C. P., & Kalantar‐Zadeh, K. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2009.06.028 · Cited by 57 · see citing works

Chylomicrons can inhibit endotoxin activity in vitro

Eichbaum, E. B., Harris, H. W., Kane, J. P., & Rapp, J. H. (1991) · Journal of Surgical Research · doi:10.1016/0022-4804(91)90143-a · Cited by 52 · see citing works

Increased levels of circulating soluble CD14 in Kawasaki disease

Takeshita, S., Nakatani, K., Tsujimoto, H., Kawamura, Y., Kawase, H., & Sekine, I. (2000) · Clinical & Experimental Immunology · doi:10.1046/j.1365-2249.2000.01120.x · Cited by 49 · see citing works

CD8 + CD38 + T Cells But Not HIV Type 1 RNA Viral Load Predict CD4 + T Cell Loss in a Predominantly Minority Female HIV + Adolescent Population

Wilson, C. M., Ellenberg, J. H., Douglas, S. D., Moscicki, A., Holland, C. A., & For The Reach Project Of The Adoles (2004) · AIDS Research and Human Retroviruses · doi:10.1089/088922204322996482 · Cited by 46 · see citing works

The −159C/T Polymorphism in the Promoter Region of the CD14 Gene Is Associated With Advanced Liver Disease and Higher Serum Levels of Acute‐Phase Proteins in Heavy Drinkers

Franco, J. C., González‐Quintela, A., Quinteiro, C., Gudé, F., Perez, L., Torre, J., & Vidal, C. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000171977.25531.7a · Cited by 45 · see citing works

Different effects of a CD14 gene polymorphism on disease outcome in patients with alcoholic liver disease and chronic hepatitis C infection

Meiler, C. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i38.6031 · Cited by 45 · see citing works

Active Immunization with a DetoxifiedEscherichia coliJ5 Lipopolysaccharide Group B Meningococcal Outer Membrane Protein Complex Vaccine Protects Animals from Experimental Sepsis

Cross, A. S., Opal, S. M., Warren, H. S., Palardy, J. E., Glaser, K., Parejo, N. A., & Bhattacharjee, A. K. (2001) · The Journal of Infectious Diseases · doi:10.1086/319297 · Cited by 43 · see citing works

Mucosal Plasma Cell Repertoire During HIV-1 Infection

Scamurra, R. W., Nelson, D. B., Lin, X. M., Miller, D. J., Silverman, G. J., Kappel, T., Thurn, J. R., Lorenz, E., Kulkarni, A. P., & Janoff, E. N. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.7.4008 · Cited by 34 · see citing works

Effect of Pro-inflammatory/Anti-inflammatory Agents on Cytokine Secretion by Peripheral Blood Mononuclear Cells in Rheumatoid Arthritis and Systemic Lupus Erythematosus

Scuderi, F., Convertino, R., Molino, N., Provenzano, C., Marino, M., Zoli, A., & Bartoccioni, E. (2003) · Autoimmunity · doi:10.1080/0891693031000079275 · Cited by 31 · see citing works

Soluble (s) CD14 and Plasmatic Lipopolysaccharides (LPS) in Patients with Chronic Hepatitis C Before and After Treatment with Interferon (IFN)-α

Jirillo, E., Amati, L., Caradonna, L., Greco, B. M., Cozzolongo, R., Cuppone, R., Piazzolla, G., Caccavo, D., Antonaci, S., & Manghisi, O. G. (1998) · Immunopharmacology and Immunotoxicology · doi:10.3109/08923979809034805 · Cited by 29 · see citing works

Assay of Endotoxin by LimulusAmebocyte Lysate

Ketchum, P. A., & Novitsky, T. J. (2003) · Humana Press eBooks · doi:10.1385/1-59259-216-3:3 · Cited by 21 · see citing works

A CD14 Domain with Lipopolysaccharide‐Binding and ‐Neutralizing Activity

Voss, S., Welte, S., Fotin‐Mleczek, M., Fischer, R., Ulmer, A. J., Jung, G., Wiesmüller, K., & Brock, R. E. (2006) · ChemBioChem · doi:10.1002/cbic.200500257 · Cited by 13 · see citing works

Lipopolysaccharide Binding Protein and sCD14 are Not Produced as Acute Phase Proteins in Cardiac Surgery

Kudlová, M., Kunes, P., Koláčková, M., Lonský, V., Manďák, J., Andrýs, C., Jankovičová, K., & Krejsek, J. (2007) · Mediators of Inflammation · doi:10.1155/2007/72356 · Cited by 9 · see citing works

Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study

Murray, D. D., Suzuki, K., Law, M. G., Trebicka, J., Neuhaus, J., Wentworth, D. N., Johnson, M. A., Vjecha, M. J., Kelleher, A. D., Emery, S., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139981 · Cited by 2,740 · see citing works

The end of AIDS: HIV infection as a chronic disease

Deeks, S. G., Lewin, S. R., & Havlir, D. V. (2013) · The Lancet · doi:10.1016/s0140-6736(13)61809-7 · Cited by 2,081 · see citing works

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

Thevaranjan, N., Puchta, A., Schulz, C., Naidoo, A., Szamosi, J. C., Verschoor, C. P., Loukov, D., Schenck, L. P., Jury, J., Foley, K. P., et al. (2017) · Cell Host & Microbe · doi:10.1016/j.chom.2017.03.002 · Cited by 1,322 · see citing works

Systemic Effects of Inflammation on Health during Chronic HIV Infection

Deeks, S. G., Tracy, R. P., & Douek, D. C. (2013) · Immunity · doi:10.1016/j.immuni.2013.10.001 · Cited by 871 · see citing works

National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2

Jacobson, T. A., Maki, K. C., Orringer, C. E., Jones, P. H., Kris-Etherton, P., Sikand, G., La Forge, R., Daniels, S. R., Wilson, D. P., Morris, P. B., et al. (2015) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.09.002 · Cited by 784 · see citing works

Cross-sectional Comparison of the Prevalence of Age-Associated Comorbidities and Their Risk Factors Between HIV-Infected and Uninfected Individuals: The AGEhIV Cohort Study

Schouten, J., Wit, F. W. N. M., Stolte, I. G., Kootstra, N. A., van der Valk, M., Geerlings, S. E., Prins, M., Reiss, P., for the AGEhIV Cohort Study Group, Reiss, P., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu701 · Cited by 755 · see citing works

Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism

Vujkovic-Cvijin, I., Dunham, R. M., Iwai, S., Maher, M. C., Albright, R. G., Broadhurst, M. J., Hernandez, R. D., Lederman, M. M., Huang, Y., Somsouk, M., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3006438 · Cited by 734 · see citing works

The impoverished gut—a triple burden of diarrhoea, stunting and chronic disease

Guerrant, R. L., DeBoer, M. D., Moore, S. R., Scharf, R. J., & Lima, A. A. M. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.239 · Cited by 604 · see citing works

Soluble Markers of Inflammation and Coagulation but Not T-Cell Activation Predict Non–AIDS-Defining Morbid Events During Suppressive Antiretroviral Treatment

Tenorio, A. R., Zheng, Y., Bosch, R. J., Krishnan, S., Rodriguez, B. A., Hunt, P. W., Plants, J., Seth, A., Wilson, C. C., Deeks, S. G., et al. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu254 · Cited by 551 · see citing works

HIV and Aging: State of Knowledge and Areas of Critical Need for Research. A Report to the NIH Office of AIDS Research by the HIV and Aging Working Group

High, K. P., Brennan-Ing, M., Clifford, D. B., Cohen, M. H., Currier, J., Deeks, S. G., Deren, S., Effros, R. B., Gebo, K., Goronzy, J. J., et al. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31825a3668 · Cited by 522 · see citing works

Immune Activation, Inflammation, and Non-AIDS Co-Morbidities in HIV-Infected Patients under Long-Term ART

Zicari, S., Sessa, L., Cotugno, N., Ruggiero, A., Rocchi, F., Concato, C., Rocca, S., Zangari, P., Manno, E. C., & Palma, P. (2019) · Viruses · doi:10.3390/v11030200 · Cited by 525 · see citing works

Microbial Translocation Across the GI Tract

Brenchley, J. M., & Douek, D. C. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075001 · Cited by 496 · see citing works

Microbial Translocation in the Pathogenesis of HIV Infection and AIDS

Marchetti, G. C., Tincati, C., & Silvestri, G. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00050-12 · Cited by 502 · see citing works

Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases

Sturgeon, C., & Fasano, A. (2016) · Tissue Barriers · doi:10.1080/21688370.2016.1251384 · Cited by 497 · see citing works

Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

Hunt, P. W., Sinclair, E., Rodriguez, B. A., Shive, C. L., Clagett, B. M., Funderburg, N., Robinson, J., Huang, Y., Epling, L., Martin, J. N., et al. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu238 · Cited by 481 · see citing works

Microbial translocation in HIV infection: causes, consequences and treatment opportunities

Utay, N. S., & Douek, D. C. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2848 · Cited by 473 · see citing works

HIV ‐associated chronic immune activation

Paiardini, M., & Müller-Trutwin, M. C. (2013) · Immunological Reviews · doi:10.1111/imr.12079 · Cited by 450 · see citing works

Immune activation and HIV persistence: implications for curative approaches to HIV infection

Klatt, N. R., Chomont, N., Douek, D. C., & Deeks, S. G. (2013) · Immunological Reviews · doi:10.1111/imr.12065 · Cited by 439 · see citing works

A Compositional Look at the Human Gastrointestinal Microbiome and Immune Activation Parameters in HIV Infected Subjects

Mutlu, E., Keshavarzian, A., Losurdo, J., Swanson, G. R., Siewe, B. T., Forsyth, C. B., French, A. L., Demarais, P., Sun, Y., Koenig, L., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003829 · Cited by 438 · see citing works

HIV and Inflammation: Mechanisms and Consequences

Hunt, P. W. (2012) · Current HIV/AIDS Reports · doi:10.1007/s11904-012-0118-8 · Cited by 431 · see citing works

Is HIV a Model of Accelerated or Accentuated Aging?

Pathai, S., Bajillan, H., LANDAY, A. L., & High, K. P. (2013) · The Journals of Gerontology Series A · doi:10.1093/gerona/glt168 · Cited by 418 · see citing works

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

Monaco, C. L., Gootenberg, D. B., Zhao, G., Handley, S. A., Ghebremichael, M. S., Lim, E. S., Lankowski, A. J., Baldridge, M. T., Wilen, C. B., Flagg, M., et al. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.02.011 · Cited by 405 · see citing works

Microbial translocation, immune activation, and HIV disease

Klatt, N. R., Funderburg, N., & Brenchley, J. M. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.09.001 · Cited by 390 · see citing works

The effect of HAART-induced HIV suppression on circulating markers of inflammation and immune activation

Wada, N., Jacobson, L. P., Margolick, J. B., Breen, E. C., Macatangay, B. J. C., Penugonda, S., Martı́nez-Maza, O., & Bream, J. H. (2014) · AIDS · doi:10.1097/qad.0000000000000545 · Cited by 383 · see citing works

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

Leeansyah, E., Ganesh, A., Quigley, M. F., Sönnerborg, A. B., Andersson, J., Hunt, P. W., Somsouk, M., Deeks, S. G., Martin, J. N., Moll, M., et al. (2012) · Blood · doi:10.1182/blood-2012-07-445429 · Cited by 372 · see citing works

Residual Immune Dysregulation Syndrome in Treated HIV infection

Lederman, M. M., Funderburg, N., Sékaly, R., Klatt, N. R., & Hunt, P. W. (2013) · Advances in immunology · doi:10.1016/b978-0-12-407707-2.00002-3 · Cited by 348 · see citing works

Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy

Imamichi, H., Dewar, R. L., Adelsberger, J. W., Rehm, C. A., O’Doherty, U., Paxinos, E. E., Fauci, A. S., & Lane, H. C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1609057113 · Cited by 344 · see citing works

Immunologic Failure Despite Suppressive Antiretroviral Therapy Is Related to Activation and Turnover of Memory CD4 Cells

Lederman, M. M., Calabrese, L. H., Funderburg, N., Clagett, B. M., Medvik, K., Bonilla, H. F., Gripshover, B., Salata, R. A., Taege, A. J., Lisgaris, M. V., et al. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir507 · Cited by 328 · see citing works

CD4 T follicular helper cell dynamics during SIV infection

Petrovas, C., Yamamoto, T., Gerner, M. Y., Boswell, K. L., Wloka, K., Smith, E. C., Ambrozak, D. R., Utay, N. S., Timmer, K. J., Sun, X., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci63039 · Cited by 317 · see citing works

Higher Levels of CRP, D-dimer, IL-6, and Hyaluronic Acid Before Initiation of Antiretroviral Therapy (ART) Are Associated With Increased Risk of AIDS or Death

Boulware, D. R., Hullsiek, K. H., Puronen, C. E., Rupert, A. W., Baker, J. V., French, M. A., Bohjanen, P. R., Novak, R. M., Neaton, J. D., & Sereti, I. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir134 · Cited by 314 · see citing works

Impact of Multi-Targeted Antiretroviral Treatment on Gut T Cell Depletion and HIV Reservoir Seeding during Acute HIV Infection

Ananworanich, J., Schuetz, A., Vandergeeten, C., Sereti, I., de Souza, M. S., Rerknimitr, R., Dewar, R. L., Marovich, M., van Griensven, F., Sékaly, R., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033948 · Cited by 312 · see citing works

Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection

Sandler, N. G., Koh, C., Roque, A., Eccleston, J. L., Siegel, R. B., Demino, M., Kleiner, D. E., Deeks, S. G., Liang, T. J., Heller, T., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.06.063 · Cited by 307 · see citing works

Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals

Vázquez-Castellanos, J. F., Villar, S. S., Latorre, A., Artacho, A., Ferrús, M. L., Madrid, N., Vallejo, A., Sainz, T., Martı́nez-Botas, J., Ferrando‐Martínez, S., et al. (2014) · Mucosal Immunology · doi:10.1038/mi.2014.107 · Cited by 303 · see citing works

CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study

Mussini, C., Lorenzini, P., Cozzi‐Lepri, A., Lapadula, G., Marchetti, G. C., Nicastri, E., Cingolani, A., Lichtner, M., Antinori, A., Gori, A., et al. (2015) · The Lancet HIV · doi:10.1016/s2352-3018(15)00006-5 · Cited by 297 · see citing works

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

Katlama, C., Deeks, S. G., Autran, B., Martínez‐Picado, J., van Lunzen, J., Rouzioux, C., Miller, M. D., Vella, S., Schmitz, J. E., Ahlers, J. D., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60104-x · Cited by 292 · see citing works

Alcohol Use and Human Immunodeficiency Virus (HIV) Infection: Current Knowledge, Implications, and Future Directions

Williams, E. C., Hahn, J. A., Saitz, R., Bryant, K., Lira, M. C., & Samet, J. H. (2016) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.13204 · Cited by 294 · see citing works

Environmental Enteric Dysfunction: Pathogenesis, Diagnosis, and Clinical Consequences

Keusch, G. T., Denno, D. M., Black, R. E., Duggan, C., Guerrant, R. L., Lavery, J. V., Nataro, J. P., Rosenberg, I. H., Ryan, E. T., Tarr, P. I., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu485 · Cited by 294 · see citing works

Stunting Is Characterized by Chronic Inflammation in Zimbabwean Infants

Prendergast, A. J., Rukobo, S., Chasekwa, B., Mutasa, K., Ntozini, R., Mbuya, M. N. N., Jones, A. D., Moulton, L. H., Stoltzfus, R. J., & Humphrey, J. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086928 · Cited by 294 · see citing works

Ageing and inflammation in patients with HIV infection

Nasi, M., De Biasi, S., Gibellini, L., Bianchini, E., Pecorini, S., Bacca, V, Guaraldi, G., Mussini, C., Pinti, M., & Cossarizza, A. (2016) · Clinical and Experimental Immunology · doi:10.1111/cei.12814 · Cited by 277 · see citing works

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

Sereti, I., Krebs, S. J., Phanuphak, N., Fletcher, J. L. K., Slike, B. M., Pinyakorn, S., O’Connell, R. J., Rupert, A. W., Chomont, N., Valcour, V., et al. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw683 · Cited by 271 · see citing works

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

Zevin, A. S., McKinnon, L. R., Burgener, A., & Klatt, N. R. (2015) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000234 · Cited by 268 · see citing works

Immunologic Biomarkers, Morbidity, and Mortality in Treated HIV Infection

Hunt, P. W., Lee, S. A., & Siedner, M. J. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw275 · Cited by 268 · see citing works

HIV Status, Burden of Comorbid Disease, and Biomarkers of Inflammation, Altered Coagulation, and Monocyte Activation

So‐Armah, K., McGinnis, K. A., Baker, J. V., Gibert, C. L., Butt, A. A., Bryant, K. J., Goetz, M. B., Tracy, R. P., Oursler, K. K., Rimland, D., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis406 · Cited by 264 · see citing works

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

Schuetz, A., Deléage, C., Sereti, I., Rerknimitr, R., Phanuphak, N., Phuang‐Ngern, Y., Estes, J. D., Utay, N. S., Sukhumvittaya, S., Marovich, M., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004543 · Cited by 263 · see citing works

Enteropathies in the Developing World: Neglected Effects on Global Health

Prendergast, A. J., & Kelly, P. M. (2012) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2012.11-0743 · Cited by 260 · see citing works

Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway

Bowers, N. L., Helton, E. S., Huijbregts, R. P. H., Goepfert, P., Heath, S. L., & Hel, Z. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003993 · Cited by 256 · see citing works

HIV infection and cardiovascular disease

Hemkens, L. G., & Bucher, H. C. (2014) · European Heart Journal · doi:10.1093/eurheartj/eht528 · Cited by 251 · see citing works

Inflammation, immune activation, and cardiovascular disease in HIV

Nou, E., Lo, J., & Grinspoon, S. K. (2016) · AIDS · doi:10.1097/qad.0000000000001109 · Cited by 232 · see citing works

Soluble CD14 is a nonspecific marker of monocyte activation

Shive, C. L., Jiang, W., Anthony, D. D., & Lederman, M. M. (2015) · AIDS · doi:10.1097/qad.0000000000000735 · Cited by 232 · see citing works

Inflammation, Immune Activation, and Antiretroviral Therapy in HIV

Hileman, C. O., & Funderburg, N. (2017) · Current HIV/AIDS Reports · doi:10.1007/s11904-017-0356-x · Cited by 233 · see citing works

HIV infection and coronary heart disease: mechanisms and management

Hsue, P. Y., & Waters, D. D. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0219-9 · Cited by 232 · see citing works

The HIV Reservoir in Monocytes and Macrophages

Wong, M. E., Jaworowski, A., & Hearps, A. C. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01435 · Cited by 226 · see citing works

Biomarkers of Microbial Translocation and Macrophage Activation: Association With Progression of Subclinical Atherosclerosis in HIV-1 Infection

Kelesidis, T., Kendall, M. A., Yang, O. O., Hodis, H. N., & Currier, J. S. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis545 · Cited by 218 · see citing works

Shared monocyte subset phenotypes in HIV-1 infection and in uninfected subjects with acute coronary syndrome

Funderburg, N., Zidar, D. A., Shive, C. L., Lioi, A. B., Mudd, J. C., Musselwhite, L. W., Simon, D. I., Costa, M. A., Rodriguez, B. A., Sieg, S. F., et al. (2012) · Blood · doi:10.1182/blood-2012-05-433946 · Cited by 216 · see citing works

Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection

Dillon, S. M., Lee, E. J., Kotter, C. V., Austin, G. L., Gianella, S., Siewe, B. T., Smith, D. M., LANDAY, A. L., McManus, M. C., Robertson, C. E., et al. (2015) · Mucosal Immunology · doi:10.1038/mi.2015.33 · Cited by 216 · see citing works

Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil

Guerrant, R. L., Leite, Á. M., Pinkerton, R., de Medeiros, P. H. Q. S., Cavalcante, P. A., DeBoer, M. D., Kosek, M. N., Duggan, C., Gewirtz, A. T., Kagan, J. C., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158772 · Cited by 216 · see citing works

Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon

Broadhurst, M. J., Ardeshir, A., Kanwar, B., Mirpuri, J., Gundra, U. M., Leung, J. M., Wiens, K. E., Vujkovic-Cvijin, I., Kim, C. C., Yarovinsky, F., et al. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1003000 · Cited by 211 · see citing works

Noncalcified Coronary Atherosclerotic Plaque and Immune Activation in HIV-Infected Women

Fitch, K. V., Srinivasa, S., Abbara, S., Burdo, T. H., Williams, K. C., Eneh, P., Lo, J., & Grinspoon, S. K. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit508 · Cited by 206 · see citing works

Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count

Marchetti, G. C., Cozzi‐Lepri, A., Merlini, E., Bellistrì, G. M., Castagna, A., Galli, M., Verucchi, G., Antinori, A., Costantini, A., Giacometti, A., et al. (2011) · AIDS · doi:10.1097/qad.0b013e3283471d10 · Cited by 204 · see citing works

Does an Index Composed of Clinical Data Reflect Effects of Inflammation, Coagulation, and Monocyte Activation on Mortality Among Those Aging With HIV?

Justice, A. C., Freiberg, M. S., Tracy, R. P., Kuller, L. H., Tate, J., Goetz, M. B., Fiellin, D. A., Vanasse, G. J., Butt, A. A., Rodriguez‐Barradas, M. C., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cir989 · Cited by 204 · see citing works

An internationally generalizable risk index for mortality after one year of antiretroviral therapy

Tate, J. P., Justice, A. C., Hughes, M. D., Bonnet, F., Reiss, P., Mocroft, A., Nattermann, J., Lampe, F. C., Bucher, H. C., Sterling, T. R., et al. (2012) · AIDS · doi:10.1097/qad.0b013e32835b8c7f · Cited by 199 · see citing works

Metabolic disease in HIV infection

Lake, J. E., & Currier, J. S. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70271-8 · Cited by 198 · see citing works

HIV as a Cause of Immune Activation and Immunosenescence

Sokoya, T., Steel, H. C., Nieuwoudt, M., & Rossouw, T. M. (2017) · Mediators of Inflammation · doi:10.1155/2017/6825493 · Cited by 194 · see citing works

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

Rotger, M., Dalmau, J., Rauch, A., McLaren, P. J., Bosinger, S. E., Martínez, R., Utay, N. S., Roque, A., Liebner, J. C., Battegay, M., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45235 · Cited by 188 · see citing works

Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression

Mudd, J. C., & Brenchley, J. M. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw258 · Cited by 189 · see citing works

The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure

Campbell, J. H., Hearps, A. C., Martin, G. E., Williams, K. C., & Crowe, S. M. (2014) · AIDS · doi:10.1097/qad.0000000000000408 · Cited by 182 · see citing works

Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation

Gandhi, R. T., McMahon, D. K., Bosch, R. J., Lalama, C. M., Cyktor, J. C., Macatangay, B. J. C., Rinaldo, C. R., Riddler, S. A., Hogg, E., Godfrey, C. C., et al. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006285 · Cited by 181 · see citing works

Monocytes as Regulators of Inflammation and HIV-Related Comorbidities during cART

Anzinger, J. J., Butterfield, T. R., Angelovich, T. A., Crowe, S. M., & Palmer, C. S. (2014) · Journal of Immunology Research · doi:10.1155/2014/569819 · Cited by 185 · see citing works

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

Traba, J., Kwarteng-Siaw, M., Okoli, T. C., Li, J., Huffstutler, R. D., Bray, A., Waclawiw, M. A., Han, K., Pelletier, M., Sauve, A. A., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci83260 · Cited by 180 · see citing works

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

Kim, C., Nazli, A., Rojas, O. L., Chege, D., Alidina, Z., Huibner, S., Mujib, S., Benko, E., Kovacs, C., Shin, L., et al. (2012) · Mucosal Immunology · doi:10.1038/mi.2012.72 · Cited by 184 · see citing works

Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques

Klatt, N. R., Canary, L., Sun, X., Vinton, C. L., Funderburg, N., Morcock, D. R., Quiñones, M., Deming, C., Perkins, M. R., Hazuda, D. J., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci66227 · Cited by 171 · see citing works

Loss of Circulating CD4 T Cells with B Cell Helper Function during Chronic HIV Infection

Boswell, K. L., Paris, R., Boritz, E., Ambrozak, D. R., Yamamoto, T., Darko, S. W., Wloka, K., Wheatley, A. K., Narpala, S., McDermott, A. B., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003853 · Cited by 166 · see citing works

Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

Mavigner, M., Cazabat, M., Dubois, M., L'Faqihi, F.-E., Réquena, M., Pasquier, C., Klopp, P., Amar, J., Alric, L., Barange, K., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci59011 · Cited by 166 · see citing works

Association of Functional Impairment with Inflammation and Immune Activation in HIV Type 1–Infected Adults Receiving Effective Antiretroviral Therapy

Erlandson, K. M., Allshouse, A. A., Jankowski, C. M., Lee, E. J., Rufner, K. M., Palmer, B. E., Wilson, C. C., MaWhinney, S., Kohrt, W. M., & Campbell, T. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit147 · Cited by 166 · see citing works

Rosuvastatin Reduces Vascular Inflammation and T-cell and Monocyte Activation in HIV-Infected Subjects on Antiretroviral Therapy

Funderburg, N., Jiang, Y., Debanne, S. M., Labbato, D. E., Juchnowski, S. M., Ferrari, B., Clagett, B. M., Robinson, J., Lederman, M. M., & McComsey, G. A. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000478 · Cited by 162 · see citing works

HIV infection induces age-related changes to monocytes and innate immune activation in young men that persist despite combination antiretroviral therapy

Hearps, A. C., Maisa, A., Cheng, W., Angelovich, T. A., Lichtfuss, G. F., Palmer, C. S., LANDAY, A. L., Jaworowski, A., & Crowe, S. M. (2012) · AIDS · doi:10.1097/qad.0b013e328351f756 · Cited by 159 · see citing works

Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy

Babu, H., Ambikan, A. T., Gabriel, E. E., Akusjärvi, S. S., Palaniappan, A. N., Sundaraj, V., Mupanni, N. R., Sperk, M., Cheedarla, N., Sridhar, R., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01965 · Cited by 149 · see citing works

Evidence for Innate Immune System Activation in HIV Type 1–Infected Elite Controllers

Krishnan, S., Wilson, E. M. P., Sheikh, V., Rupert, A. W., Mendoza, D., Yang, J., Lempicki, R. A., Migueles, S. A., & Sereti, I. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit581 · Cited by 148 · see citing works

Increased Platelet and Microparticle Activation in HIV Infection

Mayne, E. S., Funderburg, N., Sieg, S. F., Asaad, R. J., Kalinowska, M., Rodriguez, B. A., Schmaier, A. H., Stevens, W. S., & Lederman, M. M. (2011) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3182439355 · Cited by 146 · see citing works

Rosuvastatin Treatment Reduces Markers of Monocyte Activation in HIV-Infected Subjects on Antiretroviral Therapy

Funderburg, N., Jiang, Y., Debanne, S. M., Storer, N. J., Labbato, D. E., Clagett, B. M., Robinson, J., Lederman, M. M., & McComsey, G. A. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit748 · Cited by 146 · see citing works

Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection

Tincati, C., Douek, D. C., & Marchetti, G. C. (2016) · AIDS Research and Therapy · doi:10.1186/s12981-016-0103-1 · Cited by 146 · see citing works

Lipid Abnormalities and Inflammation in HIV Inflection

Funderburg, N., & Mehta, N. N. (2016) · Current HIV/AIDS Reports · doi:10.1007/s11904-016-0321-0 · Cited by 143 · see citing works

Plasma Soluble CD163 Level Independently Predicts All-Cause Mortality in HIV-1–Infected Individuals

Knudsen, T. B., Ertner, G., Petersen, J., Møller, H. J., Moestrup, S. K., Eugen‐Olsen, J., Kronborg, G., & Benfield, T. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw263 · Cited by 141 · see citing works

Significance and Clinical Management of Persistent Low-Level Viremia and Very-Low-Level Viremia in HIV-1-Infected Patients

Ryscavage, P., Kelly, S. G., Li, J. Z., Harrigan, P. R., & Taiwo, B. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00076-14 · Cited by 141 · see citing works

A Plasma Biomarker Signature of Immune Activation in HIV Patients on Antiretroviral Therapy

Kamat, A., Misra, V., Cassol, E., Ancuța, P., Yan, Z., Li, C., Morgello, S., & Gabuzda, D. H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030881 · Cited by 139 · see citing works

Dysbiotic bacteria translocate in progressive SIV infection

Klase, Z. A., Ortiz, A. M., Deléage, C., Mudd, J. C., Quiñones, M., Schwartzman, E., Klatt, N. R., Canary, L., Estes, J. D., & Brenchley, J. M. (2015) · Mucosal Immunology · doi:10.1038/mi.2014.128 · Cited by 137 · see citing works

Inflammation in HIV and Its Impact on Atherosclerotic Cardiovascular Disease

Obare, L. M., Temu, T. M., Mallal, S. A., & Wanjalla, C. N. (2024) · Circulation Research · doi:10.1161/circresaha.124.323891 · Cited by 147 · see citing works

Abnormal Myocardial Function Is Related to Myocardial Steatosis and Diffuse Myocardial Fibrosis in HIV-Infected Adults

Thiara, D., Liu, C. Y., Raman, F., Mangat, S. A., Purdy, J., Duarte, H. A., Schmidt, N., Hur, J., Sibley, C. T., Bluemke, D. A., et al. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiv274 · Cited by 133 · see citing works

Soluble CD14 is independently associated with coronary calcification and extent of subclinical vascular disease in treated HIV infection

Longenecker, C. T., Jiang, Y., Orringer, C. E., Gilkeson, R., Debanne, S. A., Funderburg, N., Lederman, M. M., Storer, N. J., Labbato, D. E., & McComsey, G. A. (2013) · AIDS · doi:10.1097/qad.0000000000000158 · Cited by 131 · see citing works

HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities

Tedaldi, E., Minniti, N. L., & Fischer, T. (2015) · BioMed Research International · doi:10.1155/2015/641913 · Cited by 134 · see citing works

Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: A review

Girard, M. P., Osmanov, S., Assossou, O. M., & Kiény, M.-P. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.06.085 · Cited by 128 · see citing works

Entry inhibitors and their use in the treatment of HIV-1 infection

Haqqani, A. A., & Tilton, J. C. (2013) · Antiviral Research · doi:10.1016/j.antiviral.2013.03.017 · Cited by 129 · see citing works

Molecular Characterization of Stool Microbiota in HIV-Infected Subjects by Panbacterial and Order-Level 16S Ribosomal DNA (rDNA) Quantification and Correlations With Immune Activation

Ellis, C. L., Ma, Z.-M., Mann, S. K., Li, C., Wu, J., Knight, T. H., Yotter, T., Hayes, T. L., Maniar, A., Troia-Cancio, P. V., et al. (2011) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31821a603c · Cited by 129 · see citing works

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

Pérez‐Santiago, J., Gianella, S., Massanella, M., Spina, C. A., Karris, M., Var, S. R., Patel, D. R., Jordan, P. S., Young, J. A., Little, S. J., et al. (2013) · AIDS · doi:10.1097/qad.0b013e3283611816 · Cited by 126 · see citing works

Pathogenesis and clinical implications of HIV-related anemia in 2013

Redig, A. J., & Berliner, N. (2013) · Hematology · doi:10.1182/asheducation-2013.1.377 · Cited by 125 · see citing works

Effect of Probiotics (Saccharomyces boulardii) on Microbial Translocation and Inflammation in HIV-Treated Patients

Villar-García, J., Hernández, J. J., Güerri‐Fernández, R., González, A., Lerma, E., Guelar, A., Saenz, D. C., Sorlí, L., Montero, M., Horcajada, J. P., et al. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000468 · Cited by 124 · see citing works

Markers of inflammation and CD8 T ‐cell activation, but not monocyte activation, are associated with subclinical carotid artery disease in HIV ‐infected individuals

Longenecker, C. T., Funderburg, N., Jiang, Y., Debanne, S. M., Storer, N. J., Labbato, D. E., Lederman, M. M., & McComsey, G. (2013) · HIV Medicine · doi:10.1111/hiv.12013 · Cited by 122 · see citing works

Differential effects of antiretrovirals on microbial translocation and gut microbiota composition of HIV‐infected patients

Villanueva-Millán, M. J., Pérez‐Matute, P., Recio‐Fernández, E., Rosales, J. M. L., & Oteo, J. A. (2017) · Journal of the International AIDS Society · doi:10.7448/ias.20.1.21526 · Cited by 122 · see citing works

Age-Associated Changes in Monocyte and Innate Immune Activation Markers Occur More Rapidly in HIV Infected Women

Martin, G. E., Gouillou, M., Hearps, A. C., Angelovich, T. A., Cheng, A. C., Lynch, F., Cheng, W., Paukovics, G., Palmer, C. S., Novak, R. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055279 · Cited by 119 · see citing works

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C. E., Pace, M. J., Csala, A., Leitman, E. M., Moonsamy, A., McGregor, C., Hurst, J. M., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aag1048 · Cited by 119 · see citing works

Predict Mortality in

(2016)

High Soluble CD14 Levels at Primary HIV-1 Infection Predict More Rapid Disease Progression

Krastinova, E., Lécuroux, C., Leroy, C., Seng, R., Cabie, A., Rami, A., Venet, A., Meyer, L., & Goujard, C. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiv145 · Cited by 40 · see citing works

Elevated Levels of Serum-Soluble CD14 in Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Correlation to Disease Progression and Clinical Events

Lien, E., Aukrust, P., Sundan, A., Müller, F., Frøland, S. S., & Espevik, T. (1998) · Blood · doi:10.1182/blood.v92.6.2084 · Cited by 172 · see citing works

Association of Plasma Soluble Vascular Cell Adhesion Molecule-1 and sCD14 With Mortality in HIV-1–Infected West African Adults With High CD4 Counts

Affi, R., Gabillard, D., Dunyach‐Remy, C., Ntakpe, J.-B., Moh, R., Badjé, A., Kouamé, G. M., Karcher, S., Carrou, J. L., Danel, C., et al. (2020) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000002533 · Cited by 11 · see citing works

Study of the plasma levels of soluble CD14 in HIV infected patients

Maes, N. (2012) · Document Server@UHasselt (UHasselt)