Yeo, Giles S. H.

Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

Farooqi, I. S., Keogh, J. M., Yeo, G. S. H., Lank, E. J., Cheetham, T., & O'Rahilly, S. (2003) · New England Journal of Medicine

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 1,778

The genetics of obesity: From discovery to biology

Loos, R. J. F., & Yeo, G. S. H. (2022) · Nature Reviews Genetics

Genetic Associations and EpidemiologyRegulation of Appetite and Obesity

Cited by 1,291

A frameshift mutation in MC4R associated with dominantly inherited human obesity

Yeo, G. S. H., Farooqi, I. S., Aminian, S., Halsall, D. J., Stanhope, R. G., & O'Rahilly, S. (1998) · Nature Genetics

Regulation of Appetite and ObesityGenetic Associations and Epidemiology

Cited by 1,159

GDF15 mediates the effects of metformin on body weight and energy balance

Coll, A. P., Chen, M., Taskar, P., Rimmington, D., Patel, S., Tadross, J. A., Cimino, I., Yang, M., Welsh, P., Virtue, S., et al. (2020) · Nature

GDF15 and Related BiomarkersRegulation of Appetite and Obesity

Cited by 584

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

Azizan, E. A. B., Poulsen, H., Tuluc, P., Zhou, J., Clausen, M. V., Lieb, A., Maniero, C., Garg, S., Bochukova, E. G., Zhao, W., et al. (2013) · Nature Genetics

Hormonal Regulation and HypertensionAdrenal and Paraganglionic Tumors

Cited by 544

Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake

Adriaenssens, A. E., Biggs, E. K., Darwish, T., Tadross, J., Sukthankar, T., Girish, M., Polex-Wolf, J., Lam, B. Y., Zvetkova, I., Pan, W., et al. (2019) · Cell Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 324

Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs

Zivraj, K. H., Tung, Y. C. L., Piper, M., Gumy, L., Fawcett, J. W., Yeo, G. S. H., & Holt, C. E. (2010) · The Journal of Neuroscience

Axon Guidance and Neuronal SignalingRNA Research and Splicing

Cited by 315

Serotonin activates the hypothalamic–Pituitary–Adrenal axis via serotonin 2C receptor stimulation

Heisler, L. K., Pronchuk, N., Nonogaki, K., Zhou, L., Raber, J., Tung, L., Yeo, G. S. H., O'Rahilly, S., Colmers, W. F., Elmquist, J. K., et al. (2007) · Journal of Neuroscience

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 292

HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus

Steuernagel, L., Lam, B. Y. H., Klemm, P., Dowsett, G. K. C., Bauder, C. A., Tadross, J. A., Hitschfeld, T. S., del Rio Martin, A., Chen, W., de Solis, A. J., et al. (2022) · Nature Metabolism

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 267

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, J. J., Reimann, F., & Gribble, F. M. (2016) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 223

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

Dalgaard, K., Landgraf, K., Heyne, S., Lempradl, A., Longinotto, J., Gossens, K., Ruf, M., Orthofer, M., Strogantsev, R., Selvaraj, M., et al. (2016) · Cell

Genetic Syndromes and ImprintingEpigenetics and DNA Methylation

Cited by 190

Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort

Wade, K. H., Lam, B. Y. H., Melvin, A., Pan, W., Corbin, L. J., Hughes, D. A., Rainbow, K., Chen, J.-H., Duckett, K., Liu, X., et al. (2021) · Nature Medicine

Regulation of Appetite and ObesityGenetic Associations and Epidemiology

Cited by 133

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing

Dowsett, G. K. C., Lam, B. Y. H., Tadross, J. A., Cimino, I., Rimmington, D., Coll, A. P., Polex-Wolf, J., Knudsen, L. B., Pyke, C., & Yeo, G. S. H. (2021) · Molecular Metabolism

Regulation of Appetite and ObesitySingle-cell and spatial transcriptomics

Cited by 98

The implications of defining obesity as a disease: a report from the Association for the Study of Obesity 2021 annual conference

Luli, M., Yeo, G., Farrell, E., Ogden, J., Parretti, H., Frew, E., Bevan, S., Brown, A., Logue, J., Menon, V., et al. (2023) · eClinicalMedicine

Obesity and Health PracticesObesity, Physical Activity, Diet

Cited by 66

Impaired Autophagy in CD11b + Dendritic Cells Expands CD4 + Regulatory T Cells and Limits Atherosclerosis in Mice

Clement, M., Raffort, J., Lareyre, F., Tsiantoulas, D., Newland, S., Lu, Y., Masters, L., Harrison, J., Saveljeva, S., Ma, M. K. L., et al. (2019) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesAutophagy in Disease and Therapy

Cited by 44

Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression

Wagner, S., Brierley, D. I., Leeson-Payne, A., Jiang, W., Chianese, R., Lam, B. Y. H., Dowsett, G. K. C., Cristiano, C., Lyons, D., Reimann, F., et al. (2023) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 32

Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets

Sandovici, I., Hammerle, C. M., Cooper, W. N., Smith, N. H., Tarry-Adkins, J. L., Dunmore, B. J., Bauer, J., Andrews, S. R., Yeo, G. S. H., Ozanne, S. E., et al. (2016) · Diabetologia

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 31