Perlis, Roy H.

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen, Wray, N. R., 23andMe, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 3,005

Molecular genetics of attention-deficit/hyperactivity disorder

Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005) · Biological Psychiatry

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 2,357

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, Stahl, E. A., BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., et al. (2019) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,519

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Psychiatric GWAS Consortium Bipolar Disorder Working Group, Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., et al. (2011) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,344

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Wellcome Trust Case Control Consortium, Ferreira, M. A. R., O'Donovan, M. C., Meng, Y. A., Jones, I. R., Ruderfer, D. M., Jones, L., Fan, J., Kirov, G., Perlis, R. H., et al. (2008) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,237

A mega-analysis of genome-wide association studies for major depressive disorder

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H. R., Boomsma, D. I., et al. (2013) · Molecular Psychiatry

Genetic Associations and EpidemiologyBipolar Disorder and Treatment

Cited by 1,120

Long-Term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (STEP-BD)

Perlis, R. H., Miyahara, S., Marangell, L. B., Wisniewski, S. R., Ostacher, M., DelBello, M. P., Bowden, C. L., Sachs, G. S., & Nierenberg, A. A. (2004) · Biological Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 852

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

Hyde, C. L., Nagle, M. W., Tian, C., Chen, X., Paciga, S. A., Wendland, J. R., Tung, J. Y., Hinds, D. A., Perlis, R. H., & Winslow, A. R. (2016) · Nature Genetics

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 784

The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

Pacchiarotti, I., Bond, D. J., Baldessarini, R. J., Nolen, W. A., Grunze, H., Licht, R. W., Post, R. M., Berk, M., Goodwin, G. M., Sachs, G. S., et al. (2013) · American Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 770

Predictors of Recurrence in Bipolar Disorder: Primary Outcomes From the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

Perlis, R. H., Ostacher, M. J., Patel, J. K., Marangell, L. B., Zhang, H., Wisniewski, S. R., Ketter, T. A., Miklowitz, D. J., Otto, M. W., Gyulai, L., et al. (2006) · American Journal of Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 689

MAJOR DEPRESSIVE DISORDER IN DSM-5: IMPLICATIONS FOR CLINICAL PRACTICE AND RESEARCH OF CHANGES FROM DSM-IV: Review: Major Depressive Disorder in DSM-5

Uher, R., Payne, J. L., Pavlova, B., & Perlis, R. H. (2014) · Depression and Anxiety

Treatment of Major DepressionMental Health and Psychiatry

Cited by 456

Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms

Uher, R., Perlis, R. H., Henigsberg, N., Zobel, A., Rietschel, M., Mors, O., Hauser, J., Dernovsek, M. Z., Souery, D., Bajs, M., et al. (2012) · Psychological Medicine

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 420

Personalized Medicine for Depression: Can We Match Patients With Treatments?

Simon, G. E., & Perlis, R. H. (2010) · American Journal of Psychiatry

Treatment of Major DepressionPsychotherapy Techniques and Applications

Cited by 365

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

MDD Working Group of the Psychiatric Genomics Consortium, Cai, N., Revez, J. A., Adams, M. J., Andlauer, T. F. M., Breen, G., Byrne, E. M., Clarke, T.-K., Forstner, A. J., Grabe, H. J., et al. (2020) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 344

Predicting suicidal behavior from longitudinal electronic health records.

Barak-Corren, Y., Castro, V. M., Javitt, S., Hoffnagle, A. G., Dai, Y., Perlis, R. H., Nock, M. K., Smoller, J. W., & Reis, B. Y. (2017) · American Journal of Psychiatry

Suicide and Self-Harm StudiesMachine Learning in Healthcare

Cited by 339

Manic Symptoms During Depressive Episodes in 1,380 Patients With Bipolar Disorder: Findings From the STEP-BD

Goldberg, J. F., Perlis, R. H., Bowden, C. L., Thase, M. E., Miklowitz, D. J., Marangell, L. B., Calabrese, J. R., Nierenberg, A. A., & Sachs, G. S. (2009) · American Journal of Psychiatry

Bipolar Disorder and TreatmentPersonality Disorders and Psychopathology

Cited by 322

Industry sponsorship and financial conflict of interest in the reporting of clinical trials in psychiatry

Perlis, R. H., Perlis, C. S., Wu, Y., Hwang, C., Joseph, M., & Nierenberg, A. A. (2005) · American Journal of Psychiatry

Pharmaceutical industry and healthcareGlobal Public Health Policies and Epidemiology

Cited by 318

Frequency and profile of objective cognitive deficits in hospitalized patients recovering from COVID-19

Jaywant, A., Vanderlind, W. M., Alexopoulos, G. S., Fridman, C. B., Perlis, R. H., & Gunning, F. M. (2021) · Neuropsychopharmacology

Long-Term Effects of COVID-19Intensive Care Unit Cognitive Disorders

Cited by 248

How machine-learning recommendations influence clinician treatment selections: the example of antidepressant selection

Jacobs, M., Pradier, M. F., McCoy, T. H., Perlis, R. H., Doshi-Velez, F., & Gajos, K. Z. (2021) · Translational Psychiatry

Artificial Intelligence in Healthcare and EducationExplainable Artificial Intelligence (XAI)

Cited by 247

Clinical Features of Bipolar Depression Versus Major Depressive Disorder in Large Multicenter Trials

Perlis, R. H., Brown, E., Baker, R. W., & Nierenberg, A. A. (2006) · American Journal of Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 225

Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression

Huang, J., Perlis, R. H., Lee, P. H., Rush, A. J., Fava, M., Sachs, G. S., Lieberman, J., Hamilton, S. P., Sullivan, P., Sklar, P., et al. (2010) · American Journal of Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 213

Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system

Clements, C. C., Castro, V. M., Blumenthal, S. R., Rosenfield, H. R., Murphy, S. N., Fava, M., Erb, J. L., Churchill, S. E., Kaimal, A. J., Doyle, A. E., et al. (2015) · Molecular Psychiatry

Pregnancy and Medication ImpactPrenatal Substance Exposure Effects

Cited by 197