Durocher, Daniel

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

Mellacheruvu, D., Wright, Z., Couzens, A. L., Lambert, J.-P., St-Denis, N. A., Li, T., Miteva, Y. V., Hauri, S., Sardiu, M. E., Low, T. Y., et al. (2013) · Nature Methods

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K. R., MacLeod, G., Mis, M., Zimmermann, M., Fradet-Turcotte, A., Sun, S., et al. (2015) · Cell

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 1,571

The control of DNA repair by the cell cycle

Hustedt, N., & Durocher, D. (2017) · Nature Cell Biology

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 738

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

Fradet-Turcotte, A., Canny, M. D., Escribano-Díaz, C., Orthwein, A., Leung, C. C. Y., Huang, H., Landry, M.-C., Kitevski-LeBlanc, J., Noordermeer, S. M., Sicheri, F., et al. (2013) · Nature

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 686

Regulation of DNA Damage Responses by Ubiquitin and SUMO

Jackson, S. P., & Durocher, D. (2013) · Molecular Cell

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 601

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens

Hart, T., Tong, A. H. Y., Chan, K., Van Leeuwen, J., Seetharaman, A., Aregger, M., Chandrashekhar, M., Hustedt, N., Seth, S., Noonan, A., et al. (2017) · G3 Genes|Genomes|Genetics

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 599

A Genetic Map of the Response to DNA Damage in Human Cells

Olivieri, M., Cho, T., Álvarez-Quilón, A., Li, K., Schellenberg, M. J., Zimmermann, M., Hustedt, N., Rossi, S. E., Adam, S., Melo, H., et al. (2020) · Cell

DNA Repair MechanismsCRISPR and Genetic Engineering

Cited by 551

RETRACTED ARTICLE: A mechanism for the suppression of homologous recombination in G1 cells

Orthwein, A., Noordermeer, S. M., Wilson, M. D., Landry, S., Enchev, R. I., Sherker, A., Munro, M., Pinder, J., Salsman, J., Dellaire, G., et al. (2015) · Nature

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 471

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

Nakada, S., Tai, I., Panier, S., Al-Hakim, A., Iemura, S.-I., Juang, Y.-C., O’Donnell, L., Kumakubo, A., Munro, M., Sicheri, F., et al. (2010) · Nature

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 357

Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation

Sweeney, F. D., Yang, F., Chi, A., Shabanowitz, J., Hunt, D. F., & Durocher, D. (2005) · Current Biology

DNA Repair MechanismsFungal and yeast genetics research

Cited by 237

Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

Dixon, S. J., Fedyshyn, Y., Koh, J. L. Y., Prasad, T. S. K., Chahwan, C., Chua, G., Toufighi, K., Baryshnikova, A., Hayles, J., Hoe, K.-L., et al. (2008) · Proceedings of the National Academy of Sciences

Fungal and yeast genetics researchBioinformatics and Genomic Networks

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Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks.

Panier, S., Ichijima, Y., Fradet-Turcotte, A., Leung, C. C. Y., Kaustov, L., Arrowsmith, C. H., & Durocher, D. (2012) · Molecular Cell

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 152

The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination

O'Donnell, L., Panier, S., Wildenhain, J., Tkach, J. M., Al-Hakim, A., Landry, M.-C., Escribano-Diaz, C., Szilard, R. K., Young, J. T. F., Munro, M., et al. (2010) · Molecular Cell

DNA Repair MechanismsFungal and yeast genetics research

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The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer

Adam, S., Rossi, S. E., Moatti, N., De Marco Zompit, M., Xue, Y., Ng, T. F., Álvarez-Quilón, A., Desjardins, J., Bhaskaran, V., Martino, G., et al. (2021) · Nature Cancer

DNA Repair MechanismsBRCA gene mutations in cancer

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A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae

Addinall, S. G., Downey, M., Yu, M., Zubko, M. K., Dewar, J., Leake, A., Hallinan, J., Shaw, O., James, K., Wilkinson, D. J., et al. (2008) · Genetics

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

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RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1

Setiaputra, D., Escribano-Díaz, C., Reinert, J. K., Sadana, P., Zong, D., Callen, E., Sifri, C., Seebacher, J., Nussenzweig, A., Thomä, N. H., et al. (2022) · Molecular Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

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Genome-scale chemogenomic CRISPR screens in human cells using the TKOv3 library

Olivieri, M., & Durocher, D. (2021) · STAR Protocols

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

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