Grarup, Niels

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., et al. (2016) · New England Journal of Medicine

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 189

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Wood, A. R., Jonsson, A., Jackson, A. U., Wang, N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., et al. (2017) · Diabetes

Genetic Associations and EpidemiologyPancreatic function and diabetes

Cited by 117

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., et al. (2015) · The American Journal of Clinical Nutrition

Sleep and related disordersCircadian rhythm and melatonin

Cited by 112

Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

Dallner, O. S., Marinis, J. M., Lu, Y.-H., Birsoy, K., Werner, E., Fayzikhodjaeva, G., Dill, B. D., Molina, H., Moscati, A., Kutalik, Z., et al. (2019) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 106

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

Frayling, T. M., Beaumont, R. N., Jones, S. E., Yaghootkar, H., Tuke, M. A., Ruth, K. S., Casanova, F., West, B., Locke, J., Sharp, S., et al. (2018) · Cell Reports

Fibroblast Growth Factor ResearchGenetic Associations and Epidemiology

Cited by 101

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Eriksson, J., Haring, R., Grarup, N., Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, T., Mellström, D., Pedersen, O., Nauck, M., et al. (2017) · PLOS ONE

Hormonal and reproductive studiesGenetic Associations and Epidemiology

Cited by 101

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

Kizilkaya, H. S., Sørensen, K. V., Kibsgaard, C. J., Gasbjerg, L. S., Hauser, A. S., Sparre-Ulrich, A. H., Grarup, N., & Rosenkilde, M. M. (2021) · Frontiers in Cell and Developmental Biology

Regulation of Appetite and ObesityReceptor Mechanisms and Signaling

Cited by 52

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J.-W., et al. (2022) · Nature Communications

Cardiac electrophysiology and arrhythmiasGenetic Associations and Epidemiology

Cited by 49

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus

Gjesing, A. P., Rui, G., Lauenborg, J., Have, C. T., Hollensted, M., Andersson, E., Grarup, N., Sun, J., Quan, S., Brandslund, I., et al. (2017) · Journal of the Endocrine Society

Gestational Diabetes Research and ManagementPancreatic function and diabetes

Cited by 43

GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

Iepsen, E. W., Have, C. T., Veedfald, S., Madsbad, S., Holst, J. J., Grarup, N., Pedersen, O., Brandslund, I., Holm, J.-C., Hansen, T., et al. (2020) · Cell Reports Medicine

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 43

The −250G>A Promoter Variant in Hepatic Lipase Associates with Elevated Fasting Serum High-Density Lipoprotein Cholesterol Modulated by Interaction with Physical Activity in a Study of 16,156 Danish Subjects

Grarup, N., Andreasen, C. H., Andersen, M. K., Albrechtsen, A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism

Lipid metabolism and disordersParaoxonase enzyme and polymorphisms

Cited by 34

Acute metabolic effects of melatonin—A randomized crossover study in healthy young men

Kampmann, U., Lauritzen, E. S., Grarup, N., Jessen, N., Hansen, T., Møller, N., & Støy, J. (2021) · Journal of Pineal Research

Circadian rhythm and melatoninPancreatic function and diabetes

Cited by 24

Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

Friedrich, N., Pietzner, M., Cannet, C., Thuesen, B. H., Hansen, T., Wallaschofski, H., Grarup, N., Skaaby, T., Budde, K., Pedersen, O., et al. (2017) · PLOS ONE

Thyroid Disorders and TreatmentsMetabolomics and Mass Spectrometry Studies

Cited by 23

Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake

Bojsen-Møller, K. N., Svane, M. S., Martinussen, C., Dirksen, C., Jørgensen, N. B., Jensen, J.-E. B., Jensen, C. Z., Torekov, S. S., Kristiansen, V. B., Rehfeld, J. F., et al. (2023) · International Journal of Obesity

Bariatric Surgery and OutcomesRegulation of Appetite and Obesity

Cited by 13