Pasterkamp, R. Jeroen

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Shi, Y., Lin, S., Staats, K. A., Li, Y., Chang, W.-H., Hung, S.-T., Hendricks, E., Linares, G. R., Wang, Y., Son, E. Y., et al. (2018) · Nature Medicine

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 566

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N., Westra, H.-J., Bakker, O. B., Deelen, P., et al. (2021) · Nature Genetics

Amyotrophic Lateral Sclerosis ResearchGenetic Associations and Epidemiology

Cited by 542

Semaphorin signaling: progress made and promises ahead

Zhou, Y., Gunput, R.-A. F., & Pasterkamp, R. J. (2008) · Trends in Biochemical Sciences

Axon Guidance and Neuronal SignalingNerve injury and regeneration

Cited by 307

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

van Beuningen, S. F. B., Will, L., Harterink, M., Chazeau, A., van Battum, E. Y., Frias, C. P., Franker, M. A. M., Katrukha, E. A., Stucchi, R., Vocking, K., et al. (2015) · Neuron

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 225

Semaphorin signalling during development

Jongbloets, B. C., & Pasterkamp, R. J. (2014) · Development

Axon Guidance and Neuronal SignalingDevelopmental Biology and Gene Regulation

Cited by 205

Endocannabinoids in Amygdala and Nucleus Accumbens Mediate Social Play Reward in Adolescent Rats

Trezza, V., Damsteegt, R., Manduca, A., Petrosino, S., Van Kerkhof, L. W. M., Pasterkamp, R. J., Zhou, Y., Campolongo, P., Cuomo, V., Di Marzo, V., et al. (2012) · The Journal of Neuroscience

Cannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 190

Disrupted neuronal trafficking in amyotrophic lateral sclerosis

Burk, K., & Pasterkamp, R. J. (2019) · Acta Neuropathologica

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 162

Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects

Sudria-Lopez, E., Koppers, M., de Wit, M., van der Meer, C., Westeneng, H.-J., Zundel, C. A. C., Youssef, S. A., Harkema, L., de Bruin, A., Veldink, J. H., et al. (2016) · Acta Neuropathologica

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 130

Development, wiring and function of dopamine neuron subtypes

Garritsen, O., van Battum, E. Y., Grossouw, L. M., & Pasterkamp, R. J. (2023) · Nature reviews. Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeurogenesis and neuroplasticity mechanisms

Cited by 128

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients

Manitt, C., Eng, C., Pokinko, M., Ryan, R. T., Torres-Berrío, A., Lopez, J. P., Yogendran, S. V., Daubaras, M. J. J., Grant, A., Schmidt, E. R. E., et al. (2013) · Translational Psychiatry

Neurotransmitter Receptor Influence on BehaviorAxon Guidance and Neuronal Signaling

Cited by 125

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

Siebold, C., Yamashita, T., Monnier, P. P., Mueller, B. K., & Pasterkamp, R. J. (2017) · Trends in Cell Biology

Axon Guidance and Neuronal SignalingDevelopmental Biology and Gene Regulation

Cited by 118

Semaphorin 3F Is a Bifunctional Guidance Cue for Dopaminergic Axons and Controls Their Fasciculation, Channeling, Rostral Growth, and Intracortical Targeting

Kolk, S. M., Gunput, R.-A. F., Tran, T. S., van den Heuvel, D. M. A., Prasad, A. A., Hellemons, A. J. C. G. M., Adolfs, Y., Ginty, D. D., Kolodkin, A. L., Burbach, J. P. H., et al. (2009) · The Journal of Neuroscience

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 114

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures

van Spronsen, M., van Battum, E. Y., Kuijpers, M., Vangoor, V. R., Rietman, M. L., Pothof, J., Gumy, L. F., van IJcken, W. F. J., Akhmanova, A., Pasterkamp, R. J., et al. (2013) · PLoS ONE

MicroRNA in disease regulationNeurogenesis and neuroplasticity mechanisms

Cited by 82

A double hit implicates DIAPH3 as an autism risk gene

Vorstman, J. A. S., van Daalen, E., Jalali, G. R., Schmidt, E. R. E., Pasterkamp, R. J., de Jonge, M., Hennekam, E. A. M., Janson, E., Staal, W. G., van der Zwaag, B., et al. (2011) · Molecular Psychiatry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 74

Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis

De Santis, R., Alfano, V., de Turris, V., Colantoni, A., Santini, L., Garone, M. G., Antonacci, G., Peruzzi, G., Sudria-Lopez, E., Wyler, E., et al. (2019) · Cell Reports

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

Cited by 70

Structure of the Repulsive Guidance Molecule (RGM)–Neogenin Signaling Hub

Bell, C. H., Healey, E., van Erp, S., Bishop, B., Tang, C., Gilbert, R. J. C., Aricescu, A. R., Pasterkamp, R. J., & Siebold, C. (2013) · Science

Axon Guidance and Neuronal SignalingProtein Structure and Dynamics

Cited by 65

Opposite-sex attraction in male mice requires testosterone-dependent regulation of adult olfactory bulb neurogenesis

Schellino, R., Trova, S., Cimino, I., Farinetti, A., Jongbloets, B. C., Pasterkamp, R. J., Panzica, G., Giacobini, P., De Marchis, S., & Peretto, P. (2016) · Scientific Reports

Olfactory and Sensory Function StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 28

Screening for rare variants in the coding region of ALS-associated genes at 9p21.2 and 19p13.3

Koppers, M., Groen, E. J. N., van Vught, P. W. J., van Rheenen, W., Witteveen, E., van Es, M. A., Pasterkamp, R. J., van den Berg, L. H., & Veldink, J. H. (2013) · Neurobiology of Aging

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 20

Small molecule inhibition of PIKFYVE kinase rescues gain- and loss-of-function C9ORF72 ALS/FTD disease processes in vivo

Staats, K. A., Seah, C., Sahimi, A., Wang, Y., Koutsodendris, N., Lin, S., Kim, D., Chang, W.-H., Gray, K. A., Shi, Y., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 16