Rothenberg, Ellen V.

Developmental gene networks: a triathlon on the course to T cell identity

Yui, M. A., & Rothenberg, E. V. (2014) · Nature Reviews Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 342

Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity

Zhang, J. A., Mortazavi, A., Williams, B. A., Wold, B. J., & Rothenberg, E. V. (2012) · Cell

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 337

Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus

Taghon, T., Yui, M. A., Pant, R., Diamond, R. A., & Rothenberg, E. V. (2006) · Immunity

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 312

Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation

Kueh, H. Y., Champhekar, A., Nutt, S. L., Elowitz, M. B., & Rothenberg, E. V. (2013) · Science

Gene Regulatory Network AnalysisDevelopmental Biology and Gene Regulation

Cited by 273

Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage

Anderson, M. K., Hernandez-Hoyos, G., Diamond, R. A., & Rothenberg, E. V. (1999) · Development

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 258

Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells

Hu, G., Cui, K., Fang, D., Hirose, S., Wang, X., Wangsa, D., Jin, W., Ried, T., Liu, P., Zhu, J., et al. (2018) · Immunity

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 199

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

Taghon, T., Yui, M. A., & Rothenberg, E. V. (2007) · Nature Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 195

Constitutive Expression of PU.1 in Fetal Hematopoietic Progenitors Blocks T Cell Development at the Pro-T Cell Stage

Anderson, M. K., Weiss, A. H., Hernandez-Hoyos, G., Dionne, C. J., & Rothenberg, E. V. (2002) · Immunity

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 182

TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells

Tsagaratou, A., González-Avalos, E., Rautio, S., Scott-Browne, J. P., Togher, S., Pastor, W. A., Rothenberg, E. V., Chavez, L., Lähdesmäki, H., & Rao, A. (2017) · Nature Immunology

T-cell and B-cell ImmunologyEpigenetics and DNA Methylation

Cited by 154

Fine-Scale Staging of T Cell Lineage Commitment in Adult Mouse Thymus

Yui, M. A., Feng, N., & Rothenberg, E. V. (2010) · The Journal of Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 152

Transcription factor PU.1 represses and activates gene expression in early T cells by redirecting partner transcription factor binding

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T., & Rothenberg, E. V. (2018) · Immunity

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 116

Notch/Delta signaling constrains reengineering of pro-T cells by PU.1

Franco, C. B., Scripture-Adams, D. D., Proekt, I., Taghon, T., Weiss, A. H., Yui, M. A., Adams, S. L., Diamond, R. A., & Rothenberg, E. V. (2006) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 109

Molecular Dissection of Prethymic Progenitor Entry into the T Lymphocyte Developmental Pathway

Tydell, C. C., David-Fung, E.-S., Moore, J. E., Rowen, L., Taghon, T., & Rothenberg, E. V. (2007) · The Journal of Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 99

Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development

Rothenberg, E. V., Hosokawa, H., & Ungerbäck, J. (2019) · Frontiers in Immunology

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 99

Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3

Del Real, M. M., & Rothenberg, E. V. (2013) · Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 95

Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network

Longabaugh, W. J. R., Zeng, W., Zhang, J. A., Hosokawa, H., Jansen, C. S., Li, L., Romero-Wolf, M., Liu, P., Kueh, H. Y., Mortazavi, A., et al. (2017) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 89

GATA-3 Dose-Dependent Checkpoints in Early T Cell Commitment

Scripture-Adams, D. D., Damle, S. S., Li, L., Elihu, K. J., Qin, S., Arias, A. M., Butler, R. R., Champhekar, A., Zhang, J. A., & Rothenberg, E. V. (2014) · The Journal of Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 81

Multilayered specification of the T-cell lineage fate.

Rothenberg, E. V., Zhang, J., & Li, L. (2010) · Immunological Reviews

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 81

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

Ungerbäck, J., Hosokawa, H., Wang, X., Strid, T., Williams, B. A., Sigvardsson, M., & Rothenberg, E. V. (2018) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 77

Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1

Champhekar, A., Damle, S. S., Freedman, G., Carotta, S., Nutt, S. L., & Rothenberg, E. V. (2015) · Genes & Development

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 74

Forging T-Lymphocyte Identity

Rothenberg, E. V., Ungerbäck, J., & Champhekar, A. (2016) · Advances in Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 61

Progression of regulatory gene expression states in fetal and adult pro-T-cell development

David‐Fung, E., Yui, M. A., Morales, M., Wang, H., Taghon, T., Diamond, R. A., & Rothenberg, E. V. (2006) · Immunological Reviews

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 60

Subversion of T lineage commitment by PU.1 in a clonal cell line system

Dionne, C. J., Tse, K. Y., Weiss, A. H., Franco, C. B., Wiest, D. L., Anderson, M. K., & Rothenberg, E. V. (2005) · Developmental Biology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 54

Cell-Type-Specific Activation and Repression of PU.1 by a Complex of Discrete, Functionally Specialized cis-Regulatory Elements

Zarnegar, M. A., Chen, J., & Rothenberg, E. V. (2010) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 52