Studer, Lorenz

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Chambers, S. M., Fasano, C. A., Papapetrou, E. P., Tomishima, M., Sadelain, M., & Studer, L. (2009) · Nature Biotechnology

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 3,620

Human iPSC-based modeling of late-onset disease via progerin-induced aging

Miller, J. D., Ganat, Y. M., Kishinevsky, S., Bowman, R. L., Liu, B., Tu, E. Y., Mandal, P. K., Vera, E., Shim, J.-W., Kriks, S., et al. (2013) · Cell stem cell

Pluripotent Stem Cells ResearchParkinson's Disease Mechanisms and Treatments

Cited by 777

Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

Elkabetz, Y., Panagiotakos, G., Al Shamy, G., Socci, N. D., Tabar, V., & Studer, L. (2008) · Genes & Development

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 677

Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells

Maroof, A. M., Keros, S., Tyson, J. A., Ying, S.-W., Ganat, Y. M., Merkle, F. T., Liu, B., Goulburn, A., Stanley, E. G., Elefanty, A. G., et al. (2013) · Cell Stem Cell

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 596

Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination

Wang, S., Bates, J., Li, X., Schanz, S., Chandler-Militello, D., Levine, C., Maherali, N., Studer, L., Hochedlinger, K., Windrem, M., et al. (2013) · Cell Stem Cell

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 586

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

Cebrián, C., Zucca, F. A., Mauri, P., Steinbeck, J. A., Studer, L., Scherzer, C. R., Kanter, E., Budhu, S., Mandelbaum, J., Vonsattel, J. P., et al. (2014) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 338

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

Papapetrou, E. P., Tomishima, M. J., Chambers, S. M., Mica, Y., Reed, E., Menon, J., Tabar, V., Mo, Q., Studer, L., & Sadelain, M. (2009) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 286

High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain

Zhou, T., Tan, L., Cederquist, G. Y., Fan, Y., Hartley, B. J., Mukherjee, S., Tomishima, M., Brennand, K. J., Zhang, Q., Schwartz, R. E., et al. (2017) · Cell stem cell

Mosquito-borne diseases and controlZebrafish Biomedical Research Applications

Cited by 263

Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells

Qi, Y., Zhang, X.-J., Renier, N., Wu, Z., Atkin, T., Sun, Z., Ozair, M. Z., Tchieu, J., Zimmer, B., Fattahi, F., et al. (2017) · Nature Biotechnology

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 248

An epigenetic barrier sets the timing of human neuronal maturation

Ciceri, G., Baggiolini, A., Cho, H. S., Kshirsagar, M., Benito-Kwiecinski, S., Walsh, R. M., Aromolaran, K. A., Gonzalez-Hernandez, A. J., Munguba, H., Koo, S. Y., et al. (2024) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 240

A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages

Tchieu, J., Zimmer, B., Fattahi, F., Amin, S., Zeltner, N., Chen, S., & Studer, L. (2017) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 235

NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells

Tchieu, J., Calder, E. L., Guttikonda, S. R., Gutzwiller, E. M., Aromolaran, K. A., Steinbeck, J. A., Goldstein, P. A., & Studer, L. (2019) · Nature Biotechnology

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 231

Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease

Tabar, V., Sarva, H., Lozano, A. M., Fasano, A., Kalia, S. K., Yu, K. K. H., Brennan, C., Ma, Y., Peng, S., Eidelberg, D., et al. (2025) · Nature

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 181

Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons

Riessland, M., Kolisnyk, B., Kim, T. W., Cheng, J., Ni, J., Pearson, J. A., Park, E. J., Dam, K., Acehan, D., Ramos-Espiritu, L. S., et al. (2019) · Cell Stem Cell

Telomeres, Telomerase, and SenescenceParkinson's Disease Mechanisms and Treatments

Cited by 180

Back and forth in time: Directing age in iPSC-derived lineages

Cornacchia, D., & Studer, L. (2017) · Brain Research

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 56

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Diener, J., Baggiolini, A., Pernebrink, M., Dalcher, D., Lerra, L., Cheng, P. F., Varum, S., Häusel, J., Stierli, S., Treier, M., et al. (2021) · Nature Communications

Melanoma and MAPK PathwaysEpigenetics and DNA Methylation

Cited by 34

Lessons Learned from Pioneering Neural Stem Cell Studies

Temple, S., & Studer, L. (2017) · Stem Cell Reports

Pluripotent Stem Cells ResearchBiomedical Ethics and Regulation

Cited by 29