Hayes, Matthew R.

GLP-1 Neurons in the Nucleus of the Solitary Tract Project Directly to the Ventral Tegmental Area and Nucleus Accumbens to Control for Food Intake

Alhadeff, A. L., Rupprecht, L. E., & Hayes, M. R. (2012) · Endocrinology

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 515

Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4

Kanoski, S. E., Fortin, S. M., Arnold, M., Grill, H. J., & Hayes, M. R. (2011) · Endocrinology

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 347

GLP-1 and weight loss: unraveling the diverse neural circuitry

Kanoski, S. E., Hayes, M. R., & Skibicka, K. P. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 290

The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide

Kanoski, S. E., Rupprecht, L. E., Fortin, S. M., De Jonghe, B. C., & Hayes, M. R. (2012) · Neuropharmacology

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 273

GDF15 induces anorexia through nausea and emesis

Borner, T., Shaulson, E. D., Ghidewon, M. Y., Barnett, A. B., Horn, C. C., Doyle, R. P., Grill, H. J., Hayes, M. R., & De Jonghe, B. C. (2020) · Cell Metabolism

Regulation of Appetite and ObesityGDF15 and Related Biomarkers

Cited by 255

GIP receptor agonism attenuates GLP-1 receptor agonist induced nausea and emesis in preclinical models

Borner, T., Geisler, C. E., Fortin, S. M., Cosgrove, R., Alsina-Fernandez, J., Dogra, M., Doebley, S., Sanchez-Navarro, M. J., Leon, R. M., Gaisinsky, J., et al. (2021) · Diabetes

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 202

GLP-1 acts on habenular avoidance circuits to control nicotine intake

Tuesta, L. M., Chen, Z., Duncan, A., Fowler, C. D., Ishikawa, M., Lee, B. R., Liu, X.-A., Lu, Q., Cameron, M., Hayes, M. R., et al. (2017) · Nature Neuroscience

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 200

Role of the glucagon-like-peptide-1 receptor in the control of energy balance

Hayes, M. R., De Jonghe, B. C., & Kanoski, S. E. (2010) · Physiology & Behavior

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 173

Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Decreases the Reinforcing Efficacy of Cocaine

Schmidt, H. D., Mietlicki-Baase, E. G., Ige, K. Y., Maurer, J. J., Reiner, D. J., Zimmer, D. J., Van Nest, D. S., Guercio, L. A., Wimmer, M. E., Olivos, D. R., et al. (2016) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 148

Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance

Reiner, D. J., Mietlicki-Baase, E. G., McGrath, L. E., Zimmer, D. J., Bence, K. K., Sousa, G. L., Konanur, V. R., Krawczyk, J., Burk, D. H., Kanoski, S. E., et al. (2016) · The Journal of Neuroscience

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 133

GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats

Fortin, S. M., Lipsky, R. K., Lhamo, R., Chen, J., Kim, E., Borner, T., Schmidt, H. D., & Hayes, M. R. (2020) · Science Translational Medicine

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 127

Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats

Hayes, M. R., Kanoski, S. E., Alhadeff, A. L., & Grill, H. J. (2011) · Obesity

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 110

GLP-1 Influences Food and Drug Reward

Hayes, M. R., & Schmidt, H. D. (2016) · Current Opinion in Behavioral Sciences

Neurotransmitter Receptor Influence on BehaviorRegulation of Appetite and Obesity

Cited by 108

Endogenous glucagon-like peptide-1 receptor signaling in the nucleus tractus solitarius is required for food intake control

Alhadeff, A. L., Mergler, B. D., Zimmer, D. J., Turner, C. A., Reiner, D. J., Schmidt, H. D., Grill, H. J., & Hayes, M. R. (2017) · Neuropsychopharmacology

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 102

Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity

Lee, S. J., Sanchez-Watts, G., Krieger, J.-P., Pignalosa, A., Norell, P. N., Cortella, A., Pettersen, K. G., Vrdoljak, D., Hayes, M. R., Kanoski, S. E., et al. (2018) · Molecular Metabolism

Regulation of Appetite and ObesityAdipose Tissue and Metabolism

Cited by 95

The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1

Hayes, M. R., Kanoski, S. E., De Jonghe, B. C., Leichner, T. M., Alhadeff, A. L., Fortin, S. M., Arnold, M., Langhans, W., & Grill, H. J. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 86

Glucagon-like peptide-1 receptor agonists suppress water intake independent of effects on food intake

McKay, N. J., Kanoski, S. E., Hayes, M. R., & Daniels, D. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 79

Low physical activity levels of modern Homo sapiens among free-ranging mammals

Hayes, M., Chustek, M., Heshka, S., Wang, Z., Pietrobelli, A., & Heymsfield, S. B. (2005) · International Journal of Obesity

Obesity, Physical Activity, DietPhysical Activity and Health

Cited by 60

Tirzepatide suppresses palatable food intake by selectively reducing preference for fat in rodents

Geisler, C. E., Antonellis, M. P., Trumbauer, W., Martin, J. A., Coskun, T., Samms, R. J., & Hayes, M. R. (2023) · Diabetes, Obesity and Metabolism

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 51

Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis

Borner, T., Workinger, J. L., Tinsley, I. C., Fortin, S. M., Stein, L. M., Chepurny, O. G., Holz, G. G., Wierzba, A. J., Gryko, D., Nexø, E., et al. (2020) · Cell Reports

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 39

The locus coeruleus contributes to the anorectic, nausea, and autonomic physiological effects of glucagon-like peptide-1

Fortin, S. M., Chen, J. C., Petticord, M. C., Ragozzino, F. J., Peters, J. H., & Hayes, M. R. (2023) · Science Advances

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 32

Hindbrain melanocortin 3/4 receptors modulate the food intake and body weight suppressive effects of the GLP-1 receptor agonist, liraglutide

Fortin, S. M., Chen, J., & Hayes, M. R. (2020) · Physiology & Behavior

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 10

Brain Activity Associated with Breakthrough Food Preoccupation in an Individual on Tirzepatide

Choi, W., Nho, Y.-H., Qiu, L., Chang, A., Campos, G., Seilheimer, R. L., Wilent, W. B., Bakalov, D., Firdous, N., Kerr, M., et al. (2025) · Nature Medicine

Eating Disorders and BehaviorsRegulation of Appetite and Obesity

Cited by 10