Huganir, Richard L.

Interaction of the N-Terminal Domain of the AMPA Receptor GluR4 Subunit with the Neuronal Pentraxin NP1 Mediates GluR4 Synaptic Recruitment

Sia, G.-M., Béïque, J.-C., Rumbaugh, G., Cho, R., Worley, P. F., & Huganir, R. L. (2007) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 201

Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression

Cai, X., Kallarackal, A. J., Kvarta, M. D., Goluskin, S., Gaylor, K., Bailey, A. M., Lee, H.-K., Huganir, R. L., & Thompson, S. M. (2013) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 180

Homeostatic regulation of AMPA receptor expression at single hippocampal synapses

Hou, Q., Zhang, D., Jarzylo, L., Huganir, R. L., & Man, H.-Y. (2008) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 179

Tyrosine phosphorylation and regulation of the AMPA receptor by SRC family tyrosine kinases

Hayashi, T., & Huganir, R. L. (2004) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 177

Twenty Years of SynGAP Research: From Synapses to Cognition

Gamache, T. R., Araki, Y., & Huganir, R. L. (2020) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 161

PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity

Diering, G. H., Gustina, A. S., & Huganir, R. L. (2014) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 153

Regulation of AMPA receptor function by the human memory-associated gene KIBRA

Makuch, L., Volk, L., Anggono, V., Johnson, R. C., Yu, Y., Duning, K., Kremerskothen, J., Xia, J., Takamiya, K., & Huganir, R. L. (2011) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 143

Activity-Dependent Ubiquitination of GluA1 and GluA2 Regulates AMPA Receptor Intracellular Sorting and Degradation

Widagdo, J., Chai, Y. J., Ridder, M. C., Chau, Y. Q., Johnson, R. C., Sah, P., Huganir, R. L., & Anggono, V. (2015) · Cell Reports

Neuroscience and Neuropharmacology ResearchUbiquitin and proteasome pathways

Cited by 132

Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer‐induced AMPA glutamate receptor signaling deficits

Miller, E. C., Teravskis, P. J., Dummer, B. W., Zhao, X., Huganir, R. L., & Liao, D. (2014) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 131

SynaptomeDB: an ontology-based knowledgebase for synaptic genes

Pirooznia, M., Wang, T., Avramopoulos, D., Valle, D., Thomas, G., Huganir, R. L., Goes, F. S., Potash, J. B., & Zandi, P. P. (2012) · Bioinformatics

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 125

PICK1 loss of function occludes homeostatic synaptic scaling

Anggono, V., Clem, R. L., & Huganir, R. L. (2011) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 111

Phosphorylation of AMPA receptors is required for sensory deprivation-induced homeostatic synaptic plasticity

Goel, A., Xu, L. W., Snyder, K. P., Song, L., Goenaga-Vazquez, Y., Megill, A., Takamiya, K., Huganir, R. L., & Lee, H.-K. (2011) · PLoS ONE

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 103

PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence

Hayashi-Takagi, A., Araki, Y., Nakamura, M., Vollrath, B., Duron, S. G., Yan, Z., Kasai, H., Huganir, R. L., Campbell, D. A., & Sawa, A. (2014) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 101

Developmental Expression of Ca2+-Permeable AMPA Receptors Underlies Depolarization-Induced Long-Term Depression at Mossy Fiber–CA3 Pyramid Synapses

Ho, M. T.-W., Pelkey, K. A., Topolnik, L., Petralia, R. S., Takamiya, K., Xia, J., Huganir, R. L., Lacaille, J.-C., & McBain, C. J. (2007) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 98

Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine

Zhang, K., Xu, T., Yuan, Z., Wei, Z., Yamaki, V. N., Huang, M., Huganir, R. L., & Cai, X. (2016) · Science Signaling

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 98

GluA1 Phosphorylation Contributes to Postsynaptic Amplification of Neuropathic Pain in the Insular Cortex

Qiu, S., Zhang, M., Liu, Y., Guo, Y., Zhao, H., Song, Q., Zhao, M., Huganir, R. L., Luo, J., Xu, H., et al. (2014) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchPain Mechanisms and Treatments

Cited by 97

S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis

Selvakumar, B., Jenkins, M. A., Hussain, N. K., Huganir, R. L., Traynelis, S. F., & Snyder, S. H. (2013) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 97

GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions

Mao, L., Takamiya, K., Thomas, G., Lin, D.-T., & Huganir, R. L. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 94

SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity

Araki, Y., Rajkovich, K. E., Gerber, E. E., Gamache, T. R., Johnson, R. C., Tran, T. H. N., Liu, B., Zhu, Q., Hong, I., Kirkwood, A., et al. (2024) · Science

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 92

Plasma membrane insertion of the AMPA receptor GluA2 subunit is regulated by NSF binding and Q/R editing of the ion pore

Araki, Y., Lin, D.-T., & Huganir, R. L. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 92

Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning

Volk, L., Kim, C.-H., Takamiya, K., Yu, Y., & Huganir, R. L. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 85

Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

Graves, A. R., Roth, R. H., Tan, H. L., Zhu, Q., Bygrave, A. M., Lopez-Ortega, E., Hong, I., Spiegel, A. C., Johnson, R. C., Vogelstein, J. T., et al. (2021) · eLife

Neuroscience and Neuropharmacology ResearchAdvanced Fluorescence Microscopy Techniques

Cited by 84

AMPA receptor and GEF-H1/Lfc complex regulates dendritic spine development through RhoA signaling cascade

Kang, M.-G., Guo, Y., & Huganir, R. L. (2009) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 82

Enhanced synaptic plasticity in mice with phosphomimetic mutation of the GluA1 AMPA receptor

Makino, Y., Johnson, R. C., Yu, Y., Takamiya, K., & Huganir, R. L. (2011) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 77