Hirokawa, Nobutaka

Kinesin superfamily motor proteins and intracellular transport

Hirokawa, N., Noda, Y., Tanaka, Y., & Niwa, S. (2009) · Nature Reviews Molecular Cell Biology

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 1,859

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

Hirokawa, N., Niwa, S., & Tanaka, Y. (2010) · Neuron

Microtubule and mitosis dynamicsNeuroscience and Neuropharmacology Research

Cited by 1,138

Encyclopedia of Neuroscience

Binder, M. D., Hirokawa, N., & Windhorst, U. (2009) · Springer eBooks

Undergraduate Neuroscience Education and ResearchNeurology and Historical Studies

Cited by 900

Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria

Tanaka, Y., Kanai, Y., Okada, Y., Nonaka, S., Takeda, S., Harada, A., & Hirokawa, N. (1998) · Cell

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 654

Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons

Chen, J., Kanai, Y., Cowan, N. J., & Hirokawa, N. (1992) · Nature

Microtubule and mitosis dynamicsAlzheimer's disease research and treatments

Cited by 601

Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

Maekawa, H., Inoue, T., Ouchi, H., Jao, T.-M., Inoue, R., Nishi, H., Fujii, R., Ishidate, F., Tanaka, T., Tanaka, Y., et al. (2019) · Cell Reports

Acute Kidney Injury Researchinterferon and immune responses

Cited by 586

Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

Hirokawa, N., Pfister, K. K., Yorifuji, H., Wagner, M. C., Brady, S. T., & Bloom, G. S. (1989) · Cell

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 477

A Processive Single-Headed Motor: Kinesin Superfamily Protein KIF1A

Okada, Y., & Hirokawa, N. (1999) · Science

Microtubule and mitosis dynamicsAdvanced Fluorescence Microscopy Techniques

Cited by 468

Microtubule bundling by tau proteins in vivo: analysis of functional domains

Kanai, Y., Chen, J., & Hirokawa, N. (1992) · The EMBO Journal

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 194

Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons.

Hirokawa, N., Funakoshi, T., Sato-Harada, R., & Kanai, Y. (1996) · The Journal of cell biology

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 179

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport

Nakata, T., Niwa, S., Okada, Y., Perez, F., & Hirokawa, N. (2011) · Journal of Cell Biology

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 156

Sorting mechanisms of Tau and MAP2 in neurons: Suppressed axonal transit of MAP2 and locally regulated microtubule binding

Kanai, Y., & Hirokawa, N. (1995) · Neuron

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 144

Direct visualization of the microtubule lattice seam both in vitro and in vivo

Kikkawa, M., Ishikawa, T., Nakata, T., Wakabayashi, T., & Hirokawa, N. (1994) · The Journal of Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 135

High‐resolution cryo‐EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations

Kikkawa, M., & Hirokawa, N. (2006) · The EMBO Journal

Microtubule and mitosis dynamicsEnzyme Structure and Function

Cited by 125

Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport

Shima, T., Morikawa, M., Kaneshiro, J., Kambara, T., Kamimura, S., Yagi, T., Iwamoto, H., Uemura, S., Shigematsu, H., Shirouzu, M., et al. (2018) · Journal of Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 125

Competition between motor molecules (kinesin and cytoplasmic dynein) and fibrous microtubule-associated proteins in binding to microtubules

Hagiwara, H., Yorifuji, H., Sato-Yoshitake, R., & Hirokawa, N. (1994) · Journal of Biological Chemistry

Microtubule and mitosis dynamicsAlzheimer's disease research and treatments

Cited by 115

The effects of dephosphorylation on the structure of the projections of neurofilament

Hisanaga, S., & Hirokawa, N. (1989) · The Journal of Neuroscience

Skin and Cellular Biology ResearchNuclear Structure and Function

Cited by 90

The molecular structure of adrenal medulla kinesin

Hisanaga, S., Murofushi, H., Okuhara, K., Sato, R., Masuda, Y., Sakai, H., & Hirokawa, N. (1989) · Cell Motility

Microtubule and mitosis dynamicsProtein Structure and Dynamics

Cited by 63

Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport

Nakajima, K., Takei, Y., Tanaka, Y., Nakagawa, T., Nakata, T., Noda, Y., Setou, M., & Hirokawa, N. (2002) · Molecular and Cellular Biology

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 31