Amich, Jorge

The regulation of zinc homeostasis by the ZafA transcriptional activator is essential for Aspergillus fumigatus virulence

Moreno, M. Á., Ibrahim‐Granet, O., Vicentefranqueira, R., Amich, J., Ave, P., Leal, F., Latgé, J., & Calera, J. A. (2007) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 135

Aspergillus fumigatus Survival in Alkaline and Extreme Zinc-Limiting Environments Relies on the Induction of a Zinc Homeostasis System Encoded by the zrfC and aspf2 Genes

Amich, J., Vicentefranqueira, R., Leal, F., & Calera, J. A. (2010) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 105

The ZrfC alkaline zinc transporter is required for Aspergillus fumigatus virulence and its growth in the presence of the Zn/Mn-chelating protein calprotectin: Zinc and virulence in Aspergillus fumigatus

Amich, J., Vicentefranqueira, R., Mellado, E., Ruiz-Carmuega, A., Leal, F., & Calera, J. A. (2014) · Cellular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 84

Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus

Dietl, A.-M., Amich, J., Leal, S., Beckmann, N., Binder, U., Beilhack, A., Pearlman, E., & Haas, H. (2016) · Virulence

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 77

Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant

Amich, J., Dümig, M., O'Keeffe, G., Binder, J., Doyle, S., Beilhack, A., & Krappmann, S. (2016) · Infection and Immunity

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 48

Point Mutation or Overexpression of Aspergillus fumigatus cyp51B, Encoding Lanosterol 14α-Sterol Demethylase, Leads to Triazole Resistance

Handelman, M., Meir, Z., Scott, J., Shadkchan, Y., Liu, W., Ben-Ami, R., Amich, J., & Osherov, N. (2021) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 30

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

Rhijn, N. V., Zhao, C., Al-Furaji, N., Storer, I., Valero, C., Gago, S., Chown, H., Baldin, C., Fortune-Grant, R., Shuraym, H. B., et al. (2023) · Nature Communications

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 30

Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

van Rhijn, N., Zhao, C., Al-Furaiji, N., Storer, I. S. R., Valero, C., Gago, S., Chown, H., Baldin, C., Grant, R.-F., Bin Shuraym, H., et al. (2024) · Nature Communications

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 30

Targeting zinc homeostasis to combat Aspergillus fumigatus infections

Vicentefranqueira, R., Amich, J., Laskaris, P., Ibrahim-Granet, O., Latgé, J. P., Toledo, H., Leal, F., & Calera, J. A. (2015) · Frontiers in Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 27

Amino acid biosynthetic routes as drug targets for pulmonary fungal pathogens: what is known and why do we need to know more?

Amich, J., & Bignell, E. (2016) · Current Opinion in Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 26

Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole

Scott, J., Valero, C., Mato-López, Á., Donaldson, I. J., Roldán, A., Chown, H., Van Rhijn, N., Lobo-Vega, R., Gago, S., Furukawa, T., et al. (2023) · Microbiology Spectrum

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 24

The Caspofungin Paradoxical Effect is a Tolerant “Eagle Effect” in the Filamentous Fungal Pathogen Aspergillus fumigatus

Valero, C., Colabardini, A. C., de Castro, P. A., Amich, J., Bromley, M. J., & Goldman, G. H. (2022) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 23

Deciphering metabolic traits of the fungal pathogen Aspergillus fumigatus: redundancy vs. essentiality

Amich, J., & Krappmann, S. (2012) · Frontiers in Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 19

Toward the consensus of definitions for the phenomena of antifungal tolerance and persistence in filamentous fungi

Amich, J., Bromley, M., Goldman, G. H., & Valero, C. (2025) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 14