Sivaprasad, Sobha

Development and validation of a deep learning system for diabetic retinopathy and related eye diseases using retinal images from multiethnic populations with diabetes

Ting, D. S. W., Cheung, C. Y.-L., Lim, G., Tan, G. S. W., Quang, N. D., Gan, A., Hamzah, H., Garcia-Franco, R., San Yeo, I. Y., Lee, S. Y., et al. (2017) · JAMA

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 2,402

A foundation model for generalizable disease detection from retinal images

Zhou, Y., Chia, M. A., Wagner, S. K., Ayhan, M. S., Williamson, D. J., Struyven, R. R., Liu, T., Xu, M., Lozano, M. G., Woodward-Court, P., et al. (2023) · Nature

Retinal Imaging and AnalysisOphthalmology and Visual Health Research

Cited by 1,014

Artificial intelligence using deep learning to screen for referable and vision-threatening diabetic retinopathy in Africa: a clinical validation study

Bellemo, V., Lim, Z. W., Lim, G., Nguyen, Q. D., Xie, Y., Yip, M. Y. T., Hamzah, H., Ho, J., Lee, X. Q., Hsu, W., et al. (2019) · The Lancet Digital Health

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 419

Defining response to anti-VEGF therapies in neovascular AMD

Amoaku, W. M., Chakravarthy, U., Gale, R., Gavin, M., Ghanchi, F., Gibson, J., Harding, S., Johnston, R. L., Kelly, S., Lotery, A., et al. (2015) · Eye

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 355

Integrated image-based deep learning and language models for primary diabetes care

Li, J., Guan, Z., Wang, J., Cheung, C. Y., Zheng, Y., Lim, L.-L., Lim, C. C., Ruamviboonsuk, P., Raman, R., Corsino, L., et al. (2024) · Nature Medicine

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 250

Large language models and their impact in ophthalmology

Betzler, B. K., Chen, H., Cheng, C.-Y., Lee, C. S., Ning, G., Song, S. J., Lee, A. Y., Kawasaki, R., van Wijngaarden, P., Grzybowski, A., et al. (2023) · The Lancet Digital Health

Artificial Intelligence in Healthcare and EducationOphthalmology and Visual Health Research

Cited by 161

Impact of injection therapy on retinal patients with diabetic macular edema or retinal vein occlusion

Sivaprasad, S., & Oyetunde, S. (2016) · Clinical Ophthalmology

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 134

Prevalence of diabetic retinopathy in India stratified by known and undiagnosed diabetes, urban–rural locations, and socioeconomic indices: results from the SMART India population-based cross-sectional screening study

Raman, R., Vasconcelos, J. C., Rajalakshmi, R., Prevost, A. T., Ramasamy, K., Mohan, V., Mohan, D., Rani, P. K., Conroy, D., Das, T., et al. (2022) · The Lancet Global Health

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 106

Loss of chromatic sensitivity in AMD and diabetes: a comparative study

O’Neill‐Biba, M., Sivaprasad, S., Rodriguez‐Carmona, M., Wolf, J. E., & Barbur, J. L. (2010) · Ophthalmic and Physiological Optics

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 74

Changes in volume of various retinal layers over time in early and intermediate age-related macular degeneration

Lamin, A., Oakley, J. D., Dubis, A. M., Russakoff, D. B., & Sivaprasad, S. (2019) · Eye

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 57

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia

Tideman, J. W. L., Pärssinen, O., Haarman, A. E. G., Khawaja, A. P., Wedenoja, J., Williams, K. M., Biino, G., Ding, X., Kähönen, M., Lehtimäki, T., et al. (2021) · JAMA Ophthalmology

Ophthalmology and Visual Impairment StudiesGenetic Associations and Epidemiology

Cited by 56

Retinal Asymmetry in Multiple Sclerosis

Petzold, A., Chua, S. Y. L., Khawaja, A. P., Keane, P. A., Khaw, P. T., Reisman, C., Dhillon, B., Strouthidis, N. G., Foster, P. J., Patel, P. J., et al. (2021) · Brain

Multiple Sclerosis Research StudiesGlaucoma and retinal disorders

Cited by 56

A randomized controlled trial of OPT-302, a VEGF-C/D inhibitor for neovascular age-related macular degeneration

Jackson, T. L., Slakter, J., Buyse, M., Wang, K., Dugel, P. U., Wykoff, C. C., Boyer, D. S., Gerometta, M., Baldwin, M. E., Price, C. F., et al. (2023) · Ophthalmology

Retinal Diseases and TreatmentsRetinal and Macular Surgery

Cited by 55

Age-related Macular Degeneration and Modification of Systemic Complement Factor H Production Through Liver Transplantation

Khandhadia, S., Hakobyan, S., Heng, L. Z., Gibson, J., Adams, D. H., Alexander, G. J., Gibson, J. M., Martin, K. R., Menon, G., Nash, K., et al. (2013) · Ophthalmology

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 47

Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis

Parpia, S., Morris, T. P., Phillips, M. R., Wykoff, C. C., Steel, D. H., Thabane, L., Bhandari, M., Chaudhary, V., for the Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group, Sivaprasad, S., et al. (2022) · Eye

Statistical Methods in Clinical TrialsStatistical Methods and Bayesian Inference

Cited by 32

Using deep learning to detect diabetic retinopathy on handheld non-mydriatic retinal images acquired by field workers in community settings

Nunez do Rio, J. M., Nderitu, P., Raman, R., Rajalakshmi, R., Kim, R., Rani, P. K., Sivaprasad, S., Bergeles, C., for the SMART India Study Group, Raman, R., et al. (2023) · Scientific Reports

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 31

A retrospective study of the real-life utilization and effectiveness of ranibizumab therapy for neovascular age-related macular degeneration in the UK

Sivaprasad, S., Hykin, P., Chakravarthy, U., Lotery, A., McKibbin, M., & Napier, J. (2016) · Clinical Ophthalmology

Retinal Diseases and TreatmentsRetinal and Macular Surgery

Cited by 31

Does lesion size determine the success rate of photodynamic therapy for age-related macular degeneration?

Sivaprasad, S., Saleh, G. M., & Jackson, H. (2006) · Eye

Retinal Diseases and TreatmentsPhotodynamic Therapy Research Studies

Cited by 15

Real-world service costs for neovascular-AMD clinics in the United Kingdom: structured literature review and scenario analysis

Sivaprasad, S., Bailey, C., Downey, L., Gilbert, R., Gale, R., Kotagiri, A., Mahmood, S., Morgan-Warren, P., Napier, J., Narendran, N., et al. (2024) · Current Medical Research and Opinion

Health Systems, Economic Evaluations, Quality of LifeRetinal Diseases and Treatments

Cited by 15

Visual and anatomical failure of anti-VEGF therapy for retinal vascular diseases: a survival analysis of real-world data

Fu, D. J., Mishra, A. V., Quek, C., Balaskas, K., Pontikos, N., Sim, D., Sivaprasad, S., & Faes, L. (2025) · Eye

Retinal Diseases and TreatmentsRetinal and Macular Surgery

Cited by 14

Real-World Prospective Validation and Economic Evaluation of Deep Learning– Based Diabetic Retinopathy Detection From Fundus Photographs: A Systematic Review and Meta-analysis

Ran, A. R., Ding, J. L., Tang, Z., Lam, C., Nguyen, T. X., Zhou, J., Zhang, S., Fang, D., Yang, D., Ng, V., et al. (2026) · Diabetes Care

Retinal Imaging and AnalysisRetinal Diseases and Treatments

Cited by 7