Shapiro, A.M. James

International trial of the Edmonton protocol for islet transplantation

Shapiro, A. M. J., Ricordi, C., Hering, B. J., Auchincloss, H., Lindblad, R., Robertson, R. P., Secchi, A., Brendel, M. D., Berney, T., Brennan, D. C., et al. (2006) · New England Journal of Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 1,942

Improvement in outcomes of clinical islet transplantation: 1999–2010

Barton, F. B., Rickels, M. R., Alejandro, R., Hering, B. J., Wease, S., Naziruddin, B., Oberholzer, J., Odorico, J. S., Garfinkel, M. R., Levy, M., et al. (2012) · Diabetes Care

Pancreatic function and diabetesDiabetes Management and Research

Cited by 725

A DNA methylation atlas of normal human cell types

Loyfer, N., Magenheim, J., Peretz, A., Cann, G., Bredno, J., Klochendler, A., Fox-Fisher, I., Shabi-Porat, S., Hecht, M., Pelet, T., et al. (2023) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 656

Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia

Hering, B. J., Clarke, W. R., Bridges, N. D., Eggerman, T. L., Alejandro, R., Bellin, M. D., Chaloner, K., Czarniecki, C. W., Goldstein, J. S., Hunsicker, L. G., et al. (2016) · Diabetes Care

Pancreatic function and diabetesDiabetes Management and Research

Cited by 645

A prevascularized subcutaneous device-less site for islet and cellular transplantation

Pepper, A. R., Gala-Lopez, B., Pawlick, R., Merani, S., Kin, T., & Shapiro, A. M. J. (2015) · Nature Biotechnology

Pancreatic function and diabetesTissue Engineering and Regenerative Medicine

Cited by 381

p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion

Helman, A., Klochendler, A., Azazmeh, N., Gabai, Y., Horwitz, E., Anzi, S., Swisa, A., Condiotti, R., Granit, R. Z., Nevo, Y., et al. (2016) · Nature Medicine

Pancreatic function and diabetesTelomeres, Telomerase, and Senescence

Cited by 351

Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device

Shapiro, A. M. J., Thompson, D., Donner, T. W., Bellin, M. D., Hsueh, W., Pettus, J., Wilensky, J., Daniels, M., Wang, R. M., Brandon, E. P., et al. (2021) · Cell Reports Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 313

Optimal implantation site for pancreatic islet transplantation

Merani, S., Toso, C., Emamaullee, J., & Shapiro, A. M. J. (2008) · British Journal of Surgery

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 257

High Risk of Sensitization After Failed Islet Transplantation

Campbell, P. M., Senior, P. A., Salam, A., LaBranche, K., Bigam, D. L., Kneteman, N. M., Imes, S., Halpin, A., Ryan, E. A., & Shapiro, A. M. J. (2007) · American Journal of Transplantation

Pancreatic function and diabetesRenal Transplantation Outcomes and Treatments

Cited by 173

Factors Influencing the Loss of β-Cell Mass in Islet Transplantation

Emamaullee, J. A., & Shapiro, A. M. J. (2007) · Cell Transplantation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 172

The journey of islet cell transplantation and future development

Gamble, A., Pepper, A. R., Bruni, A., & Shapiro, A. M. J. (2018) · Islets

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 171

Characterization of stem-cell-derived islets during differentiation and after implantation

Cuesta-Gomez, N., Verhoeff, K., Jasra, I. T., Pawlick, R., Dadheech, N., & Shapiro, A. M. J. (2022) · Cell Reports

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 41

A spectacular year for islet and stem cell transplantation

Shapiro, A. M. J., & Verhoeff, K. (2023) · Nature Reviews Endocrinology

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 34

Scalable bioreactor-based suspension approach to generate stem cell-derived islets from healthy donor-derived iPSCs

Verhoeff, K., Cuesta-Gomez, N., Maghera, J., Dadheech, N., Pawlick, R., Smith, N., O’Gorman, D., Razavy, H., Marfil-Garza, B., Young, L. G., et al. (2025) · Transplantation

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 16