Ward, Andrew B.

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

Aller, S. G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P. M., Trinh, Y. T., Zhang, Q., Urbatsch, I. L., et al. (2009) · Science

Drug Transport and Resistance MechanismsAntibiotic Resistance in Bacteria

Cited by 1,929

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

Pallesen, J., Wang, N., Corbett, K. S., Wrapp, D., Kirchdoerfer, R. N., Turner, H. L., Cottrell, C. A., Becker, M. M., Wang, L., Shi, W., et al. (2017) · Proceedings of the National Academy of Sciences

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 1,073

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J.-P., Khayat, R., Louder, R., Pejchal, R., Sastry, M., Dai, K., et al. (2011) · Nature

HIV Research and TreatmentCarbohydrate Chemistry and Synthesis

Cited by 830

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

Jardine, J., Julien, J.-P., Menis, S., Ota, T., Kalyuzhniy, O., McGuire, A., Sok, D., Huang, P.-S., MacPherson, S., Jones, M., et al. (2013) · Science

HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research

Cited by 770

Pre-fusion structure of a human coronavirus spike protein

Kirchdoerfer, R. N., Cottrell, C. A., Wang, N., Pallesen, J., Yassine, H. M., Turner, H. L., Corbett, K. S., Graham, B. S., McLellan, J. S., & Ward, A. B. (2016) · Nature

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 765

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Pejchal, R., Doores, K. J., Walker, L. M., Khayat, R., Huang, P.-S., Wang, S.-K., Stanfield, R. L., Julien, J.-P., Ramos, A., Crispin, M., et al. (2011) · Science

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies Research

Cited by 694

Structure of the mechanically activated ion channel Piezo1

Saotome, K., Murthy, S. E., Kefauver, J. M., Whitwam, T., Patapoutian, A., & Ward, A. B. (2018) · Nature

Ion Channels and ReceptorsErythrocyte Function and Pathophysiology

Cited by 649

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

Kirchdoerfer, R. N., Wang, N., Pallesen, J., Wrapp, D., Turner, H. L., Cottrell, C. A., Corbett, K. S., Graham, B. S., McLellan, J. S., & Ward, A. B. (2018) · Scientific Reports

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 466

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

Cirelli, K. M., Carnathan, D. G., Nogal, B., Martin, J. T., Rodriguez, O. L., Upadhyay, A. A., Enemuo, C. A., Gebru, E. H., Choe, Y., Viviano, F., et al. (2019) · Cell

HIV Research and TreatmentSARS-CoV-2 and COVID-19 Research

Cited by 433

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

Yuan, M., Huang, D., Lee, C.-C. D., Wu, N. C., Jackson, A. M., Zhu, X., Liu, H., Peng, L., van Gils, M. J., Sanders, R. W., et al. (2021) · Science

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 364

Human germinal centres engage memory and naive B cells after influenza vaccination

Turner, J. S., Zhou, J. Q., Han, J., Schmitz, A. J., Rizk, A. A., Alsoussi, W. B., Lei, T., Amor, M., McIntire, K. M., Meade, P., et al. (2020) · Nature

Influenza Virus Research StudiesT-cell and B-cell Immunology

Cited by 304

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

Song, G., He, W.-T., Callaghan, S., Anzanello, F., Huang, D., Ricketts, J., Torres, J. L., Beutler, N., Peng, L., Vargas, S., et al. (2020) · Nature Communications

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 285

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Saphire, E. O., Schendel, S. L., Fusco, M. L., Gangavarapu, K., Gunn, B. M., Wec, A. Z., Halfmann, P. J., Brannan, J. M., Herbert, A. S., Qiu, X., et al. (2018) · Cell

Viral Infections and Outbreaks ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 212

Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies

Garces, F., Sok, D., Kong, L., McBride, R., Kim, H. J., Saye-Francisco, K. F., Julien, J.-P., Hua, Y., Cupo, A., Moore, J. P., et al. (2014) · Cell

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies Research

Cited by 178

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site

Strauch, E.-M., Bernard, S. M., La, D., Bohn, A. J., Lee, P. S., Anderson, C. E., Nieusma, T., Holstein, C. A., Garcia, N. K., Hooper, K. A., et al. (2017) · Nature Biotechnology

Influenza Virus Research StudiesProtein Structure and Dynamics

Cited by 119

Structural Definition of a Neutralization-sensitive Epitope on the MERS-CoV S1-NTD

Wang, N., Rosen, O., Wang, L., Turner, H. L., Stevens, L. J., Corbett, K. S., Bowman, C. A., Pallesen, J., Shi, W., Zhang, Y., et al. (2019) · Cell Reports

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 86

Visualization of the HIV-1 Env glycan shield across scales

Berndsen, Z. T., Chakraborty, S., Wang, X., Cottrell, C. A., Torres, J. L., Diedrich, J. K., López, C. A., Yates, J. R., van Gils, M. J., Paulson, J. C., et al. (2020) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchHIV Research and Treatment

Cited by 86

Broadly inhibitory antibodies against severe malaria virulence proteins

Reyes, R. A., Raghavan, S. S. R., Hurlburt, N. K., Introini, V., Kana, I. H., Jensen, R. W., Martinez-Scholze, E., Gestal-Mato, M., Bau, C. B., Fernández-Quintero, M. L., et al. (2024) · Nature

Malaria Research and ControlMonoclonal and Polyclonal Antibodies Research

Cited by 35

Broadly inhibitory antibodies to severe malaria virulence proteins

Reyes, R. A., Raghavan, S. S. R., Hurlburt, N. K., Introini, V., Bol, S., Kana, I. H., Jensen, R. W., Martinez-Scholze, E., Gestal-Mato, M., López-Gutiérrez, B., et al. (2024) · Nature

Malaria Research and ControlMonoclonal and Polyclonal Antibodies Research

Cited by 35

LipIDens: Simulation assisted interpretation of lipid densities in cryo-EM structures of membrane proteins

Ansell, T. B., Song, W., Coupland, C. E., Carrique, L., Corey, R. A., Duncan, A. L., Cassidy, C. K., Geurts, M. M. G., Rasmussen, T., Ward, A. B., et al. (2022) · Nature Communications

Advanced Electron Microscopy Techniques and ApplicationsProtein Structure and Dynamics

Cited by 31

Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain

Jojoa-Cruz, S., Burendei, B., Lee, W.-H., & Ward, A. B. (2023) · Structure

Ion channel regulation and functionIon Channels and Receptors

Cited by 20

Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain

Jojoa-Cruz, S., Burendei, B., Lee, W.-H., & Ward, A. B. (2024) · Structure

Ion channel regulation and functionIon Channels and Receptors

Cited by 20

Local structural flexibility drives oligomorphism in computationally designed protein assemblies

Khmelinskaia, A., Bethel, N. P., Fatehi, F., Antanasijevic, A., Borst, A. J., Lai, S.-H., Wang, J. Y. (., Mallik, B. B., Miranda, M. C., Watkins, A. M., et al. (2023) · Nature Structural & Molecular Biology

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 18

Local structural flexibility drives oligomorphism in computationally designed protein assemblies

Khmelinskaia, A., Bethel, N. P., Fatehi, F., Mallik, B. B., Antanasijevic, A., Borst, A. J., Lai, S.-H., Chim, H. Y., Wang, J. Y. ‘., Miranda, M. C., et al. (2025) · Nature Structural & Molecular Biology

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 18