Nizet, Victor

Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid

Doran, K. S., Engelson, E. J., Khosravi, A., Maisey, H. C., Fedtke, I., Equils, O., Michelsen, K. S., Arditi, M., Peschel, A., & Nizet, V. (2005) · Journal of Clinical Investigation

Neonatal and Maternal InfectionsBacterial Infections and Vaccines

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Molecular pathogenesis of neonatal group B streptococcal infection: no longer in its infancy

Doran, K. S., & Nizet, V. (2004) · Molecular Microbiology

Neonatal and Maternal InfectionsStreptococcal Infections and Treatments

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Role of the hypoxia inducible factors HIF in iron metabolism

Peyssonnaux, C., Nizet, V., & Johnson, R. S. (2008) · Cell Cycle

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

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The IL-8 Protease SpyCEP/ScpC of Group A Streptococcus Promotes Resistance to Neutrophil Killing

Zinkernagel, A. S., Timmer, A. M., Pence, M. A., Locke, J. B., Buchanan, J. T., Turner, C. E., Mishalian, I., Sriskandan, S., Hanski, E., & Nizet, V. (2008) · Cell Host & Microbe

Streptococcal Infections and TreatmentsNeonatal and Maternal Infections

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Ampicillin Enhances Daptomycin- and Cationic Host Defense Peptide-Mediated Killing of Ampicillin- and Vancomycin-Resistant Enterococcus faecium

Sakoulas, G., Bayer, A. S., Pogliano, J., Tsuji, B. T., Yang, S.-J., Mishra, N. N., Nizet, V., Yeaman, M. R., & Moise, P. A. (2012) · Antimicrobial Agents and Chemotherapy

Antimicrobial Peptides and ActivitiesAntibiotic Resistance in Bacteria

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Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.

Henneke, P., Takeuchi, O., Malley, R., Lien, E., Ingalls, R. R., Freeman, M. W., Mayadas, T., Nizet, V., Akira, S., Kasper, D. L., et al. (2002) · The Journal of Immunology

Immune Response and InflammationNeonatal and Maternal Infections

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How neutrophils meet their end

Lawrence, S. M., Corriden, R., & Nizet, V. (2020) · Trends in Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsCell death mechanisms and regulation

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A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

Okumura, C. Y. M., Hollands, A., Tran, D. N., Olson, J., Dahesh, S., von Köckritz-Blickwede, M., Thienphrapa, W., Corle, C., Jeung, S. N., Kotsakis, A., et al. (2012) · Journal of Molecular Medicine

Cancer, Hypoxia, and MetabolismAntimicrobial Resistance in Staphylococcus

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Recurrent infection progressively disables host protection against intestinal inflammation

Yang, W. H., Heithoff, D. M., Aziz, P. V., Sperandio, M., Nizet, V., Mahan, M. J., & Marth, J. D. (2017) · Science

Inflammatory Bowel DiseaseImmune Response and Inflammation

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Ceftaroline Restores Daptomycin Activity against Daptomycin-Nonsusceptible Vancomycin-Resistant Enterococcus faecium

Sakoulas, G., Rose, W., Nonejuie, P., Olson, J., Pogliano, J., Humphries, R., & Nizet, V. (2014) · Antimicrobial Agents and Chemotherapy

Antibiotic Resistance in BacteriaAntimicrobial Peptides and Activities

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Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation

Secundino, I., Lizcano, A., Roupé, K. M., Wang, X., Cole, J. N., Olson, J., Ali, S. R., Dahesh, S., Amayreh, L. K., Henningham, A., et al. (2016) · Journal of Molecular Medicine

Glycosylation and Glycoproteins ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms

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Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor

Grewal, P. K., Aziz, P. V., Uchiyama, S., Rubio, G. R., Lardone, R. D., Le, D., Varki, N. M., Nizet, V., & Marth, J. D. (2013) · Proceedings of the National Academy of Sciences

Glycosylation and Glycoproteins ResearchBlood Coagulation and Thrombosis Mechanisms

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Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity

Hollands, A., Corriden, R., Gysler, G., Dahesh, S., Olson, J., Raza Ali, S., Kunkel, M. T., Lin, A. E., Forli, S., Newton, A. C., et al. (2016) · Journal of Biological Chemistry

Neutrophil, Myeloperoxidase and Oxidative MechanismsAntimicrobial Peptides and Activities

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Specific inactivation of two immunomodulatory SIGLEC genes during human evolution

Wang, X., Mitra, N., Secundino, I., Banda, K., Cruz, P., Padler-Karavani, V., Verhagen, A., Reid, C., Lari, M., Rizzi, E., et al. (2012) · Proceedings of the National Academy of Sciences

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Treatment of High-Level Gentamicin-Resistant Enterococcus faecalis Endocarditis with Daptomycin plus Ceftaroline

Sakoulas, G., Nonejuie, P., Nizet, V., Pogliano, J., Crum-Cianflone, N., & Haddad, F. (2013) · Antimicrobial Agents and Chemotherapy

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Conquering Neutrophils

Döhrmann, S., Cole, J. N., & Nizet, V. (2016) · PLOS Pathogens

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HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination

Bhandari, T., Olson, J., Johnson, R. S., & Nizet, V. (2013) · Journal of Molecular Medicine

Immunotherapy and Immune ResponsesCancer, Hypoxia, and Metabolism

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A group A Streptococcus ADP-ribosyltransferase toxin stimulates a protective interleukin 1β-dependent macrophage immune response.

Lin, A. E., Beasley, F. C., Keller, N., Hollands, A., Urbano, R., Troemel, E. R., Hoffman, H. M., & Nizet, V. (2015) · mBio

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Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction

Stewart, C. M., Buffalo, C. Z., Valderrama, J. A., Henningham, A., Cole, J. N., Nizet, V., & Ghosh, P. (2016) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsStreptococcal Infections and Treatments

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Study of streptococcal hemoprotein receptor (Shr) in iron acquisition and virulence of M1T1 group A streptococcus.

Dahesh, S., Nizet, V., & Cole, J. N. (2012) · Virulence

Streptococcal Infections and TreatmentsNeonatal and Maternal Infections

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Pattern-Based Genome Mining Guides Discovery of the Antibiotic Indanopyrrole A from a Marine Streptomycete

Sweeney, D., Bogdanov, A., Chase, A. B., Castro-Falcón, G., Trinidad-Javier, A., Dahesh, S., Nizet, V., & Jensen, P. R. (2024) · Journal of Natural Products

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Interpreting roles of mutations associated with the emergence of S. aureus USA300 strains using transcriptional regulatory network reconstruction

Poudel, S., Hyun, J., Hefner, Y., Monk, J., Nizet, V., & Palsson, B. O. (2025) · eLife

Antimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

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