Xue, Kanmin

Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR

Cehajic-Kapetanovic, J., Xue, K., Martinez-Fernandez de la Camara, C., Nanda, A., Davies, A., Wood, L. J., Salvetti, A. P., Fischer, M. D., Aylward, J. W., Barnard, A. R., et al. (2020) · Nature Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 368

Deep-learning models for the detection and incidence prediction of chronic kidney disease and type 2 diabetes from retinal fundus images

Zhang, K., Liu, X., Xu, J., Yuan, J., Cai, W., Chen, T., Wang, K., Gao, Y., Nie, S., Xu, X., et al. (2021) · Nature Biomedical Engineering

Retinal Imaging and AnalysisArtificial Intelligence in Healthcare

Cited by 324

First-in-human study of the safety and viability of intraocular robotic surgery

Edwards, T. L., Xue, K., Meenink, H. C. M., Beelen, M. J., Naus, G. J. L., Simunovic, M. P., Latasiewicz, M., Farmery, A. D., de Smet, M. D., & MacLaren, R. E. (2018) · Nature Biomedical Engineering

Retinal and Macular SurgeryIntraocular Surgery and Lenses

Cited by 231

Visual Acuity after Retinal Gene Therapy for Choroideremia

Edwards, T. L., Jolly, J. K., Groppe, M., Barnard, A. R., Cottriall, C. L., Tolmachova, T., Black, G. C., Webster, A. R., Lotery, A. J., Holder, G. E., et al. (2016) · New England Journal of Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 195

Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa

Edwards, T. L., Cottriall, C. L., Xue, K., Simunovic, M. P., Ramsden, J. D., Zrenner, E., & MacLaren, R. E. (2018) · Ophthalmology

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 193

Technique of retinal gene therapy: delivery of viral vector into the subretinal space

Xue, K., Groppe, M., Salvetti, A. P., & MacLaren, R. E. (2017) · Eye

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 191

Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

Xue, K., Jolly, J. K., Barnard, A. R., Rudenko, A., Salvetti, A. P., Patrício, M. I., Edwards, T. L., Groppe, M., Orlans, H. O., Tolmachova, T., et al. (2018) · Nature Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 185

A generalist medical language model for disease diagnosis assistance

Liu, X., Liu, H., Yang, G., Jiang, Z., Cui, S., Zhang, Z., Wang, H., Tao, L., Sun, Y., Song, Z., et al. (2025) · Nature Medicine

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 183

Optimized glycemic control of type 2 diabetes with reinforcement learning: a proof-of-concept trial

Wang, G., Liu, X., Ying, Z., Yang, G., Chen, Z., Liu, Z., Zhang, M., Yan, H., Lu, Y., Gao, Y., et al. (2023) · Nature Medicine

Diabetes Management and ResearchHyperglycemia and glycemic control in critically ill and hospitalized patients

Cited by 156

First-in-Human robot-assisted subretinal drug delivery under local anesthesia

Cehajic-Kapetanovic, J., Xue, K., Edwards, T. L., Meenink, T. C., Beelen, M. J., Naus, G. J., de Smet, M. D., & MacLaren, R. E. (2022) · American Journal of Ophthalmology

Retinal and Macular SurgeryRetinal Diseases and Treatments

Cited by 78

Assessment of visual function with cotoretigene toliparvovec in X-linked retinitis pigmentosa in the randomized XIRIUS phase 2/3 study

Lam, B. L., Pennesi, M. E., Kay, C. N., Panda, S., Gow, J. A., Zhao, G., MacLaren, R. E., MacLaren, R., Aleman, T., Birch, D., et al. (2024) · Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 51

Enhancement of adeno-associated virus-mediated gene therapy using hydroxychloroquine in murine and human tissues

Chandler, L. C., Barnard, A. R., Caddy, S. L., Patrício, M. I., McClements, M. E., Fu, H., Rada, C., MacLaren, R. E., & Xue, K. (2019) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 50

Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

Chandler, L., Yusuf, I., McClements, M., Barnard, A., MacLaren, R., & Xue, K. (2020) · International Journal of Molecular Sciences

Virus-based gene therapy researchDrug-Induced Ocular Toxicity

Cited by 49

Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Chandler, L. C., McClements, M. E., Yusuf, I. H., Martinez-Fernandez de la Camara, C., MacLaren, R. E., & Xue, K. (2021) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 43

Genome-editing strategies for treating human retinal degenerations

Quinn, J., Musa, A., Kantor, A., McClements, M. E., Cehajic-Kapetanovic, J., MacLaren, R. E., & Xue, K. (2021) · Human Gene Therapy

Retinal Development and DisordersCRISPR and Genetic Engineering

Cited by 41

Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis

Quinn, J., Salman, A., Paluch, C., Jackson-Wood, M., McClements, M. E., Luo, J., Davis, S. J., Cornall, R. J., MacLaren, R. E., Dendrou, C. A., et al. (2024) · Scientific Reports

Ocular Diseases and Behçet’s SyndromeGlaucoma and retinal disorders

Cited by 32

MetaGP: A generative foundation model integrating electronic health records and multimodal imaging for addressing unmet clinical needs

Liu, F., Zhou, H., Wang, K., Yu, Y., Gao, Y., Sun, Z., Liu, S., Sun, S., Zou, Z., Li, Z., et al. (2025) · Cell Reports Medicine

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 22

Robot-assisted retinal surgery: overcoming human limitations

Xue, K., Edwards, T. L., Meenink, H. C. M., Beelen, M. J., Naus, G. J. L., Simunovic, M. P., de Smet, M. D., & MacLaren, R. E. (2019) · Retina Atlas

Retinal and Macular SurgeryIntraocular Surgery and Lenses

Cited by 18

Correcting visual loss by genetics and prosthetics

Xue, K., & MacLaren, R. E. (2020) · Current Opinion in Physiology

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 5

Enhancement of adeno-associated virus-mediated gene therapy using hydroxychloroquine in murine and human tissues

Chandler, L. C., Barnard, A. R., Caddy, S. L., Patrício, M. I., McClements, M. E., Fu, H., Rada, C., MacLaren, R. E., & Xue, K. (2023) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 2