Brown, Brian D.

Immunology of COVID-19: Current State of the Science

Vabret, N., Britton, G. J., Gruber, C., Hegde, S., Kim, J., Kuksin, M., Levantovsky, R., Malle, L., Moreira, A., Park, M. D., et al. (2020) · Immunity

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 1,623

β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma

Ruiz de Galarreta, M., Bresnahan, E., Molina-Sánchez, P., Lindblad, K. E., Maier, B., Sia, D., Puigvehi, M., Miguela, V., Casanova-Acebes, M., Dhainaut, M., et al. (2019) · Cancer Discovery

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 912

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer

Brown, B. D., Venneri, M. A., Zingale, A., Sergi, L. S., & Naldini, L. (2006) · Nature Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 484

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

Greter, M., Helft, J., Chow, A., Hashimoto, D., Mortha, A., Agudo-Cantero, J., Bogunovic, M., Gautier, E. L., Miller, J., Leboeuf, M., et al. (2012) · Immunity

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 433

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

Mullokandov, G., Baccarini, A., Ruzo, A., Jayaprakash, A. D., Tung, N., Israelow, B., Evans, M. J., Sachidanandam, R., & Brown, B. D. (2012) · Nature Methods

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 394

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

Parikh, A., Lee, C., Joseph, P., Marchini, S., Baccarini, A., Kolev, V., Romualdi, C., Fruscio, R., Shah, H., Wang, F., et al. (2014) · Nature Communications

MicroRNA in disease regulationTGF-β signaling in diseases

Cited by 258

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

Brown, B. D., Cantore, A., Annoni, A., Sergi, L. S., Lombardo, A., Della Valle, P., D'Angelo, A., & Naldini, L. (2007) · Blood

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 252

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer

Park, M. D., Reyes-Torres, I., LeBerichel, J., Hamon, P., LaMarche, N. M., Hegde, S., Belabed, M., Troncoso, L., Grout, J. A., Magen, A., et al. (2023) · Nature Immunology

Immune cells in cancerImmune Cell Function and Interaction

Cited by 251

Quiescent tissue stem cells evade immune surveillance

Agudo, J., Park, E. S., Rose, S. A., Alibo, E., Sweeney, R., Dhainaut, M., Kobayashi, K. S., Sachidanandam, R., Baccarini, A., Merad, M., et al. (2018) · Immunity

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 244

CSF‐1 Controls Cerebellar Microglia and Is Required for Motor Function and Social Interaction

Kana, V., Desland, F. A., Casanova-Acebes, M., Ayata, P., Badimon, A., Nabel, E., Yamamuro, K., Sneeboer, M., Tan, I.-L., Flanigan, M. E., et al. (2019) · Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 220

Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens

Wroblewska, A., Dhainaut, M., Ben-Zvi, B., Rose, S. A., Park, E. S., Amir, E.-A. D., Bektesevic, A., Baccarini, A., Merad, M., Rahman, A. H., et al. (2018) · Cell

CRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics

Cited by 168

The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids

Agudo, J., Ruzo, A., Tung, N., Salmon, H., Leboeuf, M., Hashimoto, D., Becker, C., Garrett-Sinha, L.-A., Baccarini, A., Merad, M., et al. (2014) · Nature Immunology

Immune Response and InflammationMicroRNA in disease regulation

Cited by 122

Targeting Macrophages with CAR T Cells Delays Solid Tumor Progression and Enhances Antitumor Immunity

Sánchez-Paulete, A. R., Mateus-Tique, J., Mollaoglu, G., Nielsen, S. R., Marks, A., Lakshmi, A., Khan, J. A., Wilk, C. M., Pia, L., Baccarini, A., et al. (2022) · Cancer Immunology Research

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 98

BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology

Bigenwald, C., Le Berichel, J., Wilk, C. M., Chakraborty, R., Chen, S. T., Tabachnikova, A., Mancusi, R., Abhyankar, H., Casanova-Acebes, M., Laface, I., et al. (2021) · Nature Medicine

Histiocytic Disorders and TreatmentsTelomeres, Telomerase, and Senescence

Cited by 83

GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions

Agudo, J., Ruzo, A., Park, E. S., Sweeney, R., Kana, V., Wu, M., Zhao, Y., Egli, D., Merad, M., & Brown, B. D. (2015) · Nature Biotechnology

T-cell and B-cell ImmunologyAnimal Genetics and Reproduction

Cited by 64

Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation

Trinh, V. Q.-H., Lee, T.-F., Lemoinne, S., Ray, K. C., Ybanez, M. D., Tsuchida, T., Carter, J. K., Agudo, J., Brown, B. D., Akat, K. M., et al. (2023) · Science Signaling

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 45

Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery

Marron, T. U., Galsky, M. D., Taouli, B., Fiel, M. I., Ward, S., Kim, E., Yankelevitz, D., Doroshow, D., Guttman-Yassky, E., Ungar, B., et al. (2022) · Nature Medicine

Breast Cancer Treatment StudiesStatistical Methods in Clinical Trials

Cited by 30