McIntyre, Roger S.

Changes in insulin resistance following antidepressant treatment mediate response in major depressive disorder

Rashidian, H., Subramaniapillai, M., Park, C., Lipsitz, O., Zuckerman, H., Cao, B., Lee, Y., Gill, H., Rodrigues, R. N., Di Vincenzo, J. D., et al. (2023) · Journal of Psychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 23

Surrogate Markers of Insulin Resistance in Predicting Major Depressive Disorder: Metabolism Metastasizes to the Brain

McIntyre, R. S. (2021) · American Journal of Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 23

Acetyl-L-carnitine and α-lipoic acid: possible neurotherapeutic agents for mood disorders?

Soczynska, J. K., Kennedy, S. H., Chow, C. S., Woldeyohannes, H. O., Konarski, J. Z., & McIntyre, R. S. (2008) · Expert Opinion on Investigational Drugs

Biochemical Acid Research StudiesTreatment of Major Depression

Cited by 23

Antidepressants and Gastric Cancer: A Nationwide Population-Based Nested Case-Control Study

Hsieh, Y.-H., Chiu, W.-C., Lin, C.-F., Chan, H.-L., Liang, H.-Y., Lee, Y., McIntyre, R. S., & Chen, V. C.-H. (2015) · PLOS ONE

Gastric Cancer Management and OutcomesInflammatory mediators and NSAID effects

Cited by 22

Selection of cognitive tests for trials of therapeutic agents

Harrison, J. E., Lam, R. W., Baune, B. T., & McIntyre, R. S. (2016) · The Lancet Psychiatry

Treatment of Major DepressionPsychological Testing and Assessment

Cited by 22

Sex differences in the mediators of functional disability in Major Depressive Disorder

Carmona, N. E., Subramaniapillai, M., Mansur, R. B., Cha, D. S., Lee, Y., Fus, D., & McIntyre, R. S. (2018) · Journal of Psychiatric Research

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

Cited by 22

The meaningful change threshold as measured by the 16-item quick inventory of depressive symptomatology in adults with treatment-resistant major depressive and bipolar disorder receiving intravenous ketamine

McIntyre, R. S., Lipsitz, O., Lui, L. M. W., Rodrigues, N. B., Gill, H., Nasri, F., Ling, R., Teopiz, K. M., Ho, R. C., Subramaniapillai, M., et al. (2021) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 21

Lisdexamfetamine dimesylate augmentation for adults with major depressive disorder and inadequate response to antidepressant monotherapy: Results from 2 phase 3, multicenter, randomized, double-blind, placebo-controlled studies

Richards, C., McIntyre, R. S., Weisler, R., Sambunaris, A., Brawman-Mintzer, O., Gao, J., Geibel, B., Dauphin, M., & Madhoo, M. (2016) · Journal of Affective Disorders

Treatment of Major DepressionBipolar Disorder and Treatment

Cited by 20

The effectiveness of intravenous ketamine in adults with treatment-resistant major depressive disorder and bipolar disorder presenting with prominent anxiety: Results from the Canadian Rapid Treatment Center of Excellence

McIntyre, R. S., Rodrigues, N. B., Lipsitz, O., Nasri, F., Gill, H., Lui, L. M., Subramaniapillai, M., Kratiuk, K., Teopiz, K., Ho, R., et al. (2021) · Journal of Psychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 20

Repurposing glucagon-like peptide-1 (GLP-1) receptor agonists for the treatment of depression: A systematic review of preclinical, observational and clinical investigations

Li, S., Sabbah, S. G., Kwan, A. T. H., & McIntyre, R. S. (2025) · European Neuropsychopharmacology

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 19

The effectiveness of repeated intravenous ketamine on subjective and objective psychosocial function in patients with treatment-resistant depression and suicidal ideation

Zhou, Y., Wang, C., Lan, X., Zheng, W., Li, H., Chao, Z., McIntyre, R. S., & Ning, Y. (2022) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 19

The Putative Impact of Metabolic Health on Default Mode Network Activity and Functional Connectivity in Neuropsychiatric Disorders

Cha, D., Michele, F., Soczynska, J., Woldeyohannes, H., Kaidanovich-Beilin, O., Carvalho, A., Malhi, G., Patel, H., Sim, K., Brietzke, E., et al. (2015) · CNS & Neurological Disorders - Drug Targets

Functional Brain Connectivity StudiesMind wandering and attention

Cited by 18

Effectiveness of intravenous ketamine in mood disorder patients with a history of neurostimulation

Rodrigues, N. B., Siegel, A., Lipsitz, O., Cha, D. S., Gill, H., Nasri, F., Simonson, K., Shekotikhina, M., Lee, Y., Subramaniapillai, M., et al. (2022) · CNS Spectrums

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 17

The Effects of Psilocybin in Adults with Major Depressive Disorder and the General Population: Findings from Neuroimaging Studies

Gill, H., Puramat, P., Patel, P., Gill, B., Marks, C. A., Rodrigues, N. B., Castle, D., Cha, D. S., Mansur, R. B., Rosenblat, J. D., et al. (2022) · Psychiatry Research

Psychedelics and Drug StudiesTreatment of Major Depression

Cited by 16

Healthcare resource use and cost associated with timing of pharmacological treatment for major depressive disorder in the United States: a real-world study

McIntyre, R. S., Prieto, R., Schepman, P., Yeh, Y.-C., Boucher, M., Shelbaya, A., Chambers, R., Gao, X., & Pappadopulos, E. (2019) · Current Medical Research and Opinion

Treatment of Major DepressionMental Health Treatment and Access

Cited by 15

Demystifying the Antidepressant Mechanism of Action of Stinels, a Novel Class of Neuroplastogens: Positive Allosteric Modulators of the NMDA Receptor

Donello, J. E., McIntyre, R. S., Pickel, D. B., & Stahl, S. M. (2025) · Pharmaceuticals

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 15

The adverse effects of smoking on health outcomes in bipolar disorder: a review and synthesis of biological mechanisms

Slyepchenko, A., Brunoni, A. R., McIntyre, R. S., Quevedo, J., & Carvalho, A. F. (2016) · Current Molecular Medicine

Bipolar Disorder and TreatmentSmoking Behavior and Cessation

Cited by 14

Digital revolution in depression: A technologies update for clinicians

Lazar, M. A., Pan, Z., Ragguett, R.-M., Lee, Y., Subramaniapillai, M., Mansur, R. B., Rodrigues, N., & McIntyre, R. S. (2017) · Personalized Medicine in Psychiatry

Digital Mental Health InterventionsArtificial Intelligence in Healthcare and Education

Cited by 14

Ketamine monotherapy versus adjunctive ketamine in adults with treatment-resistant depression: Results from the Canadian Rapid Treatment Centre of Excellence

Di Vincenzo, J. D., Lipsitz, O., Rodrigues, N. B., Lee, Y., Gill, H., Kratiuk, K., Subramaniapillai, M., Mansur, R., McIntyre, R. S., & Rosenblat, J. D. (2021) · Journal of Psychiatric Research

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 12

A systematic review of anti-suicidal effects of sedative-hypnotics and cognitive behavioral therapy for insomnia

Valentino, K., Teopiz, K., Wong, S., Le, G. H., Badulescu, S., Johnson, D., Ho, R., Rhee, T. G., Cao, B., Rosenblat, J., et al. (2025) · CNS Spectrums

Sleep and related disordersSuicide and Self-Harm Studies

Cited by 12

The Canadian Network for Mood and Anxiety Treatments (Canmat) Task Force Recommendations for the Management of Patients with Mood Disorders and Comorbid Conditions

McIntyre, R. S., Schaffer, A., & Beaulieu, S. (2012) · Annals of Clinical Psychiatry

Treatment of Major DepressionBipolar Disorder and Treatment

Cited by 11

Cognition in Major Depressive Disorder

McIntyre, R. S., Cha, D. S., & Soczynska, J. K. (2014) · Oxford University Press eBooks

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 10

Factors That Impact Treatment Decisions: Results From an Online Survey of Individuals With Bipolar and Unipolar Depression

Rosenblat, J. D., Simon, G. E., Sachs, G. S., Deetz, I., Doederlein, A., DePeralta, D., Dean, M. M., & McIntyre, R. S. (2018) · The Primary Care Companion For CNS Disorders

Treatment of Major DepressionBipolar Disorder and Treatment

Cited by 10

Frequency of use and Perceived helpfulness of Wellness Strategies for Bipolar and Unipolar Depression

Rosenblat, J. D., Simon, G. E., Sachs, G. S., Deetz, I., Doederlein, A., DePeralta, D., Dean, M. M., & McIntyre, R. S. (2018) · Annals of Clinical Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 8