Chen, Xin

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

Duncan, J. S., Whittle, M. C., Nakamura, K., Abell, A. N., Midland, A. A., Zawistowski, J. S., Johnson, N. L., Granger, D. A., Jordan, N. V., Darr, D. B., et al. (2012) · Cell

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

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Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

Huang, H.-S., Allen, J. A., Mabb, A. M., King, I. F., Miriyala, J., Taylor-Blake, B., Sciaky, N., Dutton, J. W., Lee, H.-M., Chen, X., et al. (2012) · Nature

Genetic Syndromes and ImprintingGenetics and Neurodevelopmental Disorders

Cited by 387

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Huang, X.-P., Karpiak, J., Kroeze, W. K., Zhu, H., Chen, X., Moy, S. S., Saddoris, K. A., Nikolova, V. D., Farrell, M. S., Wang, S., et al. (2015) · Nature

Receptor Mechanisms and SignalingComputational Drug Discovery Methods

Cited by 284

Neuroprotective Natural Products for Alzheimer’s Disease

Chen, X., Drew, J., Berney, W., & Lei, W. (2021) · Cells

Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatments

Cited by 236

Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex

Zawistowski, J. S., Bevill, S. M., Goulet, D. R., Stuhlmiller, T. J., Beltran, A. S., Olivares-Quintero, J. F., Singh, D., Sciaky, N., Parker, J. S., Rashid, N. U., et al. (2017) · Cancer Discovery

Melanoma and MAPK PathwaysChromatin Remodeling and Cancer

Cited by 180

A multicenter study benchmarking single-cell RNA sequencing technologies using reference samples

Chen, W., Zhao, Y., Chen, X., Yang, Z., Xu, X., Bi, Y., Chen, V., Li, J., Choi, H., Ernest, B., et al. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

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An integrated pan-cancer analysis of PSAT1: A potential biomarker for survival and immunotherapy

Feng, M., Cui, H., Tu, W., Li, L., Gao, Y., Chen, L., Li, D., Chen, X., Xu, F., Zhou, C., et al. (2022) · Frontiers in Genetics

Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics

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