Gudkov, Andrei V.

A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Komarov, P. G., Komarova, E. A., Kondratov, R. V., Christov-Tselkov, K., Coon, J. S., Chernov, M. V., & Gudkov, A. V. (1999) · Science

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 1,270

LINE1 Derepression in aged wild-type and SIRT6-deficient mice drives inflammation

Simon, M., Van Meter, M., Ablaeva, J., Ke, Z., Gonzalez, R. S., Taguchi, T., De Cecco, M., Leonova, K. I., Kogan, V., Helfand, S. L., et al. (2019) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 498

p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

Hall, B. M., Balan, V., Gleiberman, A. S., Strom, E., Krasnov, P., Virtuoso, L. P., Rydkina, E., Vujcic, S., Balan, K., Gitlin, I. I., et al. (2017) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 407

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

Hall, B. M., Balan, V., Gleiberman, A. S., Strom, E., Krasnov, P., Virtuoso, L. P., Rydkina, E., Vujcic, S., Balan, K., Gitlin, I., et al. (2016) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 357

Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence

Liu, J.-Y., Souroullas, G. P., Diekman, B. O., Krishnamurthy, J., Hall, B. M., Sorrentino, J. A., Parker, J. S., Sessions, G. A., Gudkov, A. V., & Sharpless, N. E. (2019) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 306

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway.

Korotchkina, L. G., Leontieva, O. V., Bukreeva, E. I., Demidenko, Z. N., Gudkov, A. V., & Blagosklonny, M. V. (2010) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 278

Paradoxical suppression of cellular senescence by p53

Demidenko, Z. N., Korotchkina, L. G., Gudkov, A. V., & Blagosklonny, M. V. (2010) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 273

Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells

Rossi, S. W., Jeker, L. T., Ueno, T., Kuse, S., Keller, M. P., Zuklys, S., Gudkov, A. V., Takahama, Y., Krenger, W., Blazar, B. R., et al. (2007) · Blood

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 215

Levels of HdmX expression dictate the sensitivity of normal and transformed cells to Nutlin-3

Patton, J. T., Mayo, L. D., Singhi, A. D., Gudkov, A. V., Stark, G. R., & Jackson, M. W. (2006) · Cancer Research

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 189

Hypoxia suppresses conversion from proliferative arrest to cellular senescence

Leontieva, O. V., Natarajan, V., Demidenko, Z. N., Burdelya, L. G., Gudkov, A. V., & Blagosklonny, M. V. (2012) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 169

Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody

Frescas, D., Roux, C. M., Aygun-Sunar, S., Gleiberman, A. S., Krasnov, P., Kurnasov, O. V., Strom, E., Virtuoso, L. P., Wrobel, M., Osterman, A. L., et al. (2017) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 140

Longitudinal Analysis of Blood Markers Reveals Progressive Loss of Resilience and Predicts Human Lifespan Limit

Pyrkov, T. V., Avchaciov, K., Tarkhov, A. E., Menshikov, L. I., Gudkov, A. V., & Fedichev, P. O. (2021) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsComplex Systems and Time Series Analysis

Cited by 139

Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax

Fang, X., Nevo, E., Han, L., Levanon, E. Y., Zhao, J., Avivi, A., Larkin, D., Jiang, X., Feranchuk, S., Zhu, Y., et al. (2014) · Nature Communications

Subterranean biodiversity and taxonomyGenomics and Phylogenetic Studies

Cited by 136

Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization.

Gudkov, A. V., Kazarov, A. R., Thimmapaya, R., Axenovich, S. A., Mazo, I. A., & Roninson, I. B. (1994) · Proceedings of the National Academy of Sciences

Microtubule and mitosis dynamicsTelomeres, Telomerase, and Senescence

Cited by 122

Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells

Tanne, A., Muniz, L. R., Puzio-Kuter, A., Leonova, K. I., Gudkov, A. V., Ting, D. T., Monasson, R., Cocco, S., Levine, A. J., Bhardwaj, N., et al. (2015) · Proceedings of the National Academy of Sciences

Immune Response and InflammationCancer-related molecular mechanisms research

Cited by 74

Quantitative characterization of biological age and frailty based on locomotor activity records

Pyrkov, T. V., Getmantsev, E., Zhurov, B., Avchaciov, K., Pyatnitskiy, M., Menshikov, L., Khodova, K., Gudkov, A. V., & Fedichev, P. O. (2018) · Aging

Frailty in Older AdultsGenetics, Aging, and Longevity in Model Organisms

Cited by 55

Murine mesenchymal cells that express elevated levels of the CDK inhibitor p16(Ink4a)in vivo are not necessarily senescent

Frescas, D., Hall, B. M., Strom, E., Virtuoso, L. P., Gupta, M., Gleiberman, A. S., Rydkina, E., Balan, V., Vujcic, S., Chernova, O. B., et al. (2017) · Cell Cycle

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 34

A review of the biomedical innovations for healthy longevity

Moskalev, A., Anisimov, V., Aliper, A., Artemov, A., Asadullah, K., Belsky, D., Baranova, A., de Grey, A., Dixit, V. D., Debonneuil, E., et al. (2017) · Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 22