Matthews, Paul M.

In vivo muscle magnetic resonance spectroscopy in the clinical investigation of mitochondria1 disease

Matthews, P. M., Allaire, C., Shoubridge, E. A., Karpati, G., Carpenter, S., & Arnold, D. L. (1991) · Neurology

Advanced MRI Techniques and ApplicationsMitochondrial Function and Pathology

Cited by 121

Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease

Venkataraman, A. V., Mansur, A., Rizzo, G., Bishop, C., Lewis, Y., Kocagoncu, E., Lingford-Hughes, A., Huiban, M., Passchier, J., Rowe, J. B., et al. (2022) · Science Translational Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 101

METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research

METACOHORTS Consortium, Dichgans, M., Wardlaw, J., Smith, E., Zietemann, V., Seshadri, S., Sachdev, P., Biessels, G. J., Fazekas, F., Benavente, O., et al. (2016) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 101

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with18F-PBR111 PET

Colasanti, A., Guo, Q., Muhlert, N., Giannetti, P., Onega, M., Newbould, R. D., Ciccarelli, O., Rison, S., Thomas, C., Nicholas, R., et al. (2014) · Journal of Nuclear Medicine

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 100

A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease

Tsartsalis, S., Sleven, H., Fancy, N., Wessely, F., Smith, A. M., Willumsen, N., Cheung, T. K. D., Rokicki, M. J., Chau, V., Ifie, E., et al. (2024) · Nature Communications

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 95

Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology

Nagy, Z., Esiri, M. M., LeGris, M., & Matthews, P. M. (1999) · Acta Neuropathologica

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 85

Structural brain changes in patients with recurrent major depressive disorder presenting with anxiety symptoms

Inkster, B., Rao, A. W., Ridler, K., Nichols, T. E., Saemann, P. G., Auer, D. P., Holsboer, F., Tozzi, F., Muglia, P., Merlo-Pich, E., et al. (2011) · Journal of Neuroimaging

Treatment of Major DepressionNeural and Behavioral Psychology Studies

Cited by 56

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO)

Colasanti, A., Owen, D. R., Grozeva, D., Rabiner, E. A., Matthews, P. M., Craddock, N., & Young, A. H. (2013) · Psychoneuroendocrinology

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 55

Alzheimer’s disease-related transcriptional sex differences in myeloid cells

Coales, I., Tsartsalis, S., Fancy, N., Weinert, M., Clode, D., Owen, D., & Matthews, P. M. (2022) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 49

Characterisation of premature cell senescence in Alzheimer's disease using single nuclear transcriptomics

Fancy, N. N., Smith, A. M., Caramello, A., Tsartsalis, S., Davey, K., Muirhead, R. C. J., McGarry, A., Jenkyns, M. H., Schneegans, E., Chau, V., et al. (2024) · Acta Neuropathologica

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 48

Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals

Livingston, N. R., Calsolaro, V., Hinz, R., Nowell, J., Raza, S., Gentleman, S., Tyacke, R. J., Myers, J., Venkataraman, A. V., Perneczky, R., et al. (2022) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 44

Lipoprotein markers associated with disability from multiple sclerosis

Gafson, A. R., Thorne, T., McKechnie, C. I. J., Jimenez, B., Nicholas, R., & Matthews, P. M. (2018) · Scientific Reports

Multiple Sclerosis Research StudiesLipoproteins and Cardiovascular Health

Cited by 40

Automatic Quality Control of Cardiac MRI Segmentation in Large-Scale Population Imaging

Robinson, R., Valindria, V. V., Bai, W., Suzuki, H., Matthews, P. M., Page, C., Rueckert, D., & Glocker, B. (2017) · Lecture Notes in Computer Science

Medical Image Segmentation TechniquesCardiac Imaging and Diagnostics

Cited by 37

Dichloroacetate stabilizes the mutant E1α subunit in pyruvate dehydrogenase deficiency

Morten, K. J., Beattie, P., Brown, G. K., & Matthews, P. M. (1999) · Neurology

Biochemical Acid Research StudiesMetabolism and Genetic Disorders

Cited by 29

Positron-emission tomography molecular imaging of glia and myelin in drug discovery for multiple sclerosis

Matthews, P. M., & Datta, G. (2015) · Expert Opinion on Drug Discovery

Medical Imaging Techniques and ApplicationsMultiple Sclerosis Research Studies

Cited by 28

An update on neuroimaging of multiple sclerosis

Matthews, P. M. (2004) · Current Opinion in Neurology

Multiple Sclerosis Research StudiesAdvanced Neuroimaging Techniques and Applications

Cited by 15

Characteristics of TSPO expression in marmoset EAE

Falk, I., Maric, D., Leibovitch, E., Sati, P., Lefeuvre, J., Luciano, N. J., Guy, J., Ha, S.-K., Owen, D. R., Aigbirhio, F., et al. (2025) · Journal of Neuroinflammation

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 5

Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease

Debette, S., Caro, I., Western, D., Namba, S., Sun, N., Kawaguchi, S., He, Y., Fujita, M., Roshchupkin, G., D'Aoust, T., et al. (2024) · Research Square

Cerebrovascular and genetic disordersMultiple Sclerosis Research Studies

Cited by 5

Integrative multi-omics reveal glial signatures associated with accelerated cognitive decline in Alzheimer’s disease

Schneegans, E., Fancy, N., Thomas, M., Adair, E., Willumsen, N., Papageorgopoulou, M., Chau, V., Cheung, T. K. D., Muirhead, R. C. J., Whitwell, H., et al. (2024) · medRxiv

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 2