Head, Elizabeth

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., et al. (2023) · The Lancet Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 55

Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model

Sawa, M., Overk, C., Becker, A., Derse, D., Albay, R., Weldy, K., Salehi, A., Beach, T. G., Doran, E., Head, E., et al. (2022) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 54

HNE-modified proteins in Down syndrome: Involvement in development of Alzheimer disease neuropathology

Barone, E., Head, E., Butterfield, D. A., & Perluigi, M. (2017) · Free Radical Biology and Medicine

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 53

Oxidative Stress and Proteostasis Network: Culprit and Casualty of Alzheimer’s-Like Neurodegeneration

Di Domenico, F., Head, E., Butterfield, D. A., & Perluigi, M. (2014) · Advances in Geriatrics

Alzheimer's disease research and treatmentsHeat shock proteins research

Cited by 50

Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology

Tramutola, A., Di Domenico, F., Barone, E., Arena, A., Giorgi, A., di Francesco, L., Schininà, M. E., Coccia, R., Head, E., Butterfield, D. A., et al. (2017) · Antioxidants & Redox Signaling

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 49

Caspase activation in the Alzheimer's disease brain: Tortuous and torturous

Rohn, T. T., Rissman, R. A., Head, E., & Cotman, C. W. (2002) · Drug News & Perspectives

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 48

Activation of p53 in Down Syndrome and in the Ts65Dn mouse brain is associated with a pro-apoptotic phenotype

Tramutola, A., Pupo, G., Di Domenico, F., Barone, E., Arena, A., Lanzillotta, C., Broekaart, D., Blarzino, C., Head, E., Butterfield, D. A., et al. (2016) · Journal of Alzheimer s Disease

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 40

A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease

Macciardi, F., Giulia Bacalini, M., Miramontes, R., Boattini, A., Taccioli, C., Modenini, G., Malhas, R., Anderlucci, L., Gusev, Y., Gross, T. J., et al. (2022) · GeroScience

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 37

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

Wisch, J. K., McKay, N. S., Boerwinkle, A. H., Kennedy, J., Flores, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., et al. (2024) · The Lancet Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 37

The Alzheimer's Biomarker Consortium–Down Syndrome (ABC‐DS): A 10‐year report

Handen, B. L., Mapstone, M., Hartley, S., Andrews, H., Christian, B., Lee, J. H., Tudorascu, D., Hom, C., Ances, B. M., Zaman, S., et al. (2025) · Alzheimer's & Dementia

Down syndrome and intellectual disability researchDementia and Cognitive Impairment Research

Cited by 29

Blood pressure variability and plasma Alzheimer’s disease biomarkers in older adults

Sible, I. J., Yew, B., Jang, J. Y., Alitin, J. P. M., Li, Y., Gaubert, A., Nguyen, A., Dutt, S., Blanken, A. E., Ho, J. K., et al. (2022) · Scientific Reports

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 26

Down syndrome biobank consortium: a perspective

Aldecoa, I., Barroeta, I., Carroll, S. L., Fortea, J., Gilmore, A., Ginsberg, S. D., Guzman, S. J., Hamlett, E. D., Head, E., Perez, S. E., et al. (2024) · Alzheimer's & Dementia

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 19

Amyloid-β predominant Alzheimer’s disease neuropathologic change

Kovacs, G. G., Katsumata, Y., Wu, X., Aung, K. Z., Fardo, D. W., Forrest, S. L., Alzheimer's Disease Genetics Consortium, Bowen, J. D., Crane, P. K., Jarvik, G. P., et al. (2025) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 19

The mediating role of plasma glial fibrillary acidic protein in amyloid and tau pathology in Down's syndrome

Boerwinkle, A. H., Wisch, J. K., Handen, B. L., Head, E., Mapstone, M., Rafii, M. S., O'Bryant, S. E., Krinsky‐McHale, S. J., Lai, F., Rosas, H. D., et al. (2025) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 14

Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome–Alzheimer’s disease

Farrell, C., Buhidma, Y., Mumford, P., Heywood, W. E., Hällqvist, J., Flores-Aguilar, L., Andrews, E. J., Rahimzadah, N., Taso, O. S., Doran, E., et al. (2025) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 9

Consensus meta-analysis of genome-wide association studies for Alzheimer’s disease and related dementias

EADB, Bellenguez, C., Castillo Morales, A., Amin, N., van der Lee, S. J., Muntaner, M., Parveen, K., Küçükali, F., Grenier-Boley, B., Heikkinen, S., et al. (2026) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 7

Decoding brain structure to stage Alzheimer's disease pathology in Down syndrome

Kennedy, J. T., Wisch, J. K., Dincer, A., Roman, J., Gordon, B. A., Handen, B., Benzinger, T. L. S., Head, E., Mapstone, M., Christian, B. T., et al. (2025) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchDown syndrome and intellectual disability research

Cited by 7

Disruption of hippocampal upstream regulators of mTOR and insulin pathways in Down syndrome with Alzheimer's disease neuropathology: Preliminary observations

Nordbeck, A. J., Martá‐Ariza, M., Ek Olofsson, H., Kanshin, E., Ueberheide, B., Jones, K., Sanford, B., Hamlett, E. D., Head, E., Mufson, E. J., et al. (2026) · Alzheimer's & Dementia

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 0

Dissociation of Neuropathologic Findings and Cognition: Case Report of an Apolipoprotein E ε2/ε2 Genotype

Berlau, D. J., Kahle-Wrobleski, K., Head, E., Goodus, M., Kim, R., & Kawas, C. (2007) · Archives of Neurology

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 0