Alameh, Mohamad-Gabriel

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

Alameh, M.-G., Tombácz, I., Bettini, E., Lederer, K., Ndeupen, S., Sittplangkoon, C., Wilmore, J. R., Gaudette, B. T., Soliman, O. Y., Pine, M., et al. (2021) · Immunity

Immunotherapy and Immune ResponsesImmune responses and vaccinations

Cited by 775

An ionizable lipid toolbox for RNA delivery

Han, X., Zhang, H., Butowska, K., Swingle, K. L., Alameh, M.-G., Weissman, D., & Mitchell, M. J. (2021) · Nature Communications

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 628

Nanomaterial Delivery Systems for mRNA Vaccines

Buschmann, M. D., Carrasco, M. J., Alishetty, S., Paige, M., Alameh, M. G., & Weissman, D. (2021) · Vaccines

RNA Interference and Gene DeliverySARS-CoV-2 and COVID-19 Research

Cited by 582

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

Weissman, D., Alameh, M.-G., de Silva, T., Collini, P., Hornsby, H., Brown, R., LaBranche, C. C., Edwards, R. J., Sutherland, L., Santra, S., et al. (2021) · Cell Host & Microbe

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 324

Ionizable lipid nanoparticles for in utero mRNA delivery

Riley, R. S., Kashyap, M. V., Billingsley, M. M., White, B., Alameh, M.-G., Bose, S. K., Zoltick, P. W., Li, H., Zhang, R., Cheng, A. Y., et al. (2021) · Science Advances

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 222

Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy

Swingle, K. L., Safford, H. C., Geisler, H. C., Hamilton, A. G., Thatte, A. S., Billingsley, M. M., Joseph, R. A., Mrksich, K., Padilla, M. S., Ghalsasi, A. A., et al. (2023) · Journal of the American Chemical Society

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 145

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

Swingle, K. L., Hamilton, A. G., Safford, H. C., Geisler, H. C., Thatte, A. S., Palanki, R., Murray, A. M., Han, E. L., Mukalel, A. J., Han, X., et al. (2025) · Nature

RNA Interference and Gene DeliveryPregnancy and preeclampsia studies

Cited by 129

Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models

Hajnik, R. L., Plante, J. A., Liang, Y., Alameh, M.-G., Tang, J., Bonam, S. R., Zhong, C., Adam, A., Scharton, D., Rafael, G. H., et al. (2022) · Science Translational Medicine

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing

Cited by 122

Messenger RNA-Based Vaccines Against Infectious Diseases

Alameh, M.-G., Weissman, D., & Pardi, N. (2020) · Current Topics in Microbiology and Immunology

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 96

Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus

Furey, C., Scher, G., Ye, N., Kercher, L., DeBeauchamp, J., Crumpton, J. C., Jeevan, T., Patton, C., Franks, J., Rubrum, A., et al. (2024) · Nature Communications

Influenza Virus Research StudiesVirology and Viral Diseases

Cited by 79

mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model

Sittplangkoon, C., Alameh, M.-G., Weissman, D., Lin, P. J. C., Tam, Y. K., Prompetchara, E., & Palaga, T. (2022) · Frontiers in Immunology

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 79

Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease

Palanki, R., Bose, S. K., Dave, A., White, B. M., Berkowitz, C., Luks, V., Yaqoob, F., Han, E., Swingle, K. L., Menon, P., et al. (2023) · ACS Nano

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 77

Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery

Swingle, K. L., Billingsley, M. M., Bose, S. K., White, B., Palanki, R., Dave, A., Patel, S. K., Gong, N., Hamilton, A. G., Alameh, M.-G., et al. (2022) · Journal of Controlled Release

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 64

Safety and immunogenicity of a prefusion non-stabilized spike protein mRNA COVID-19 vaccine: a phase I trial

Gatechompol, S., Kittanamongkolchai, W., Ketloy, C., Prompetchara, E., Thitithanyanont, A., Jongkaewwattana, A., Buranapraditkun, S., Alameh, M.-G., Ubolyam, S., Sophonphan, J., et al. (2022) · Nature Microbiology

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 15

Immunogenicity and Protective Efficacy of a SARS-CoV-2 mRNA Vaccine Encoding Secreted Non-Stabilized Spike Protein in Mice

Prompetchara, E., Ketloy, C., Alameh, M.-G., Tarakhet, K., Kaewpang, P., Yostrerat, N., Pitakpolrat, P., Buranapraditkun, S., Manopwisedcharoen, S., Thitithanyanont, A., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 1