DiMarchi, Richard D.

Transforming obesity: The advancement of multi-receptor drugs

Kusminski, C. M., Perez-Tilve, D., Müller, T. D., DiMarchi, R. D., Tschöp, M. H., & Scherer, P. E. (2024) · Cell

Pharmacology and Obesity TreatmentDiabetes Treatment and Management

Cited by 126

Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis

Weiss, A., Murdoch, C. C., Edmonds, K. A., Jordan, M. R., Monteith, A. J., Perera, Y. R., Rodríguez Nassif, A. M., Petoletti, A. M., Beavers, W. N., Munneke, M. J., et al. (2022) · Cell

Trace Elements in HealthHeavy Metal Exposure and Toxicity

Cited by 113

Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice

Liskiewicz, A., Khalil, A., Liskiewicz, D., Novikoff, A., Grandl, G., Maity-Kumar, G., Gutgesell, R. M., Bakhti, M., Bastidas-Ponce, A., Czarnecki, O., et al. (2023) · Nature Metabolism

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 110

Monomeric GLP-1/GIP/Glucagon Triagonism Corrects Obesity, Hepatosteatosis, and Dyslipidemia in Female Mice

Jall, S., Sachs, S., Clemmensen, C., Finan, B., Neff, F., DiMarchi, R. D., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2017) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 107

Peptide lipidation stabilizes structure to enhance biological function

Ward, B. P., Ottaway, N. L., Perez-Tilve, D., Ma, D., Gelfanov, V. M., Tschöp, M. H., & DiMarchi, R. D. (2013) · Molecular Metabolism

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 101

Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21

Kim, T., Nason, S., Holleman, C., Pepin, M., Wilson, L., Berryhill, T. F., Wende, A. R., Steele, C., Young, M. E., Barnes, S., et al. (2018) · Diabetes

Fibroblast Growth Factor ResearchDrug Transport and Resistance Mechanisms

Cited by 97

GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body weight

Vogel, H., Wolf, S., Rabasa, C., Rodriguez-Pacheco, F., Babaei, C. S., Stöber, F., Goldschmidt, J., DiMarchi, R. D., Finan, B., Tschöp, M. H., et al. (2016) · Neuropharmacology

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 86

Pharmacodynamics, pharmacokinetics and safety of multiple ascending doses of the novel dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 agonist RG 7697 in people with type 2 diabetes mellitus

Schmitt, C., Portron, A., Jadidi, S., Sarkar, N., & DiMarchi, R. (2017) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 74

Selection and progression of unimolecular agonists at the GIP, GLP-1, and glucagon receptors as drug candidates

Knerr, P. J., Mowery, S. A., Finan, B., Perez-Tilve, D., Tschöp, M. H., & DiMarchi, R. D. (2020) · Peptides

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 49

Pharmacodynamics, pharmacokinetics, safety and tolerability of the novel dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 agonist RG 7697 after single subcutaneous administration in healthy subjects

Portron, A., Jadidi, S., Sarkar, N., DiMarchi, R., & Schmitt, C. (2017) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 46

Glucagon receptor signaling regulates weight loss via central KLB receptor complexes

Nason, S. R., Antipenko, J., Presedo, N., Cunningham, S. E., Pierre, T. H., Kim, T., Paul, J. R., Holleman, C., Young, M. E., Gamble, K. L., et al. (2021) · JCI Insight

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 34

Outstanding Scientific Achievement Award Lecture 2011: Defeating Diabesity

Tschöp, M. H., & DiMarchi, R. D. (2012) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 32

GLP-1/dexamethasone inhibits food reward without inducing mood and memory deficits in mice

Décarie-Spain, L., Fisette, A., Zhu, Z., Yang, B., DiMarchi, R. D., Tschöp, M. H., Finan, B., Fulton, S., & Clemmensen, C. (2019) · Neuropharmacology

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 27

GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease

Sachs, S., Götz, A., Finan, B., Feuchtinger, A., DiMarchi, R. D., Döring, Y., Weber, C., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2023) · Cardiovascular Diabetology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 24