Köttgen, Anna

Mendelian Randomization as an Approach to Assess Causality Using Observational Data

Sekula, P., Del Greco M, F., Pattaro, C., & Köttgen, A. (2016) · Journal of the American Society of Nephrology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 2,351

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Taliun, D., Harris, D. N., Kessler, M. D., Carlson, J., Szpiech, Z. A., Torres, R., Taliun, S. A. G., Corvelo, A., Gogarten, S. M., Kang, H. M., et al. (2021) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 2,213

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,744

Genome-wide association study of blood pressure and hypertension

Levy, D., Ehret, G. B., Rice, K., Verwoert, G. C., Launer, L. J., Dehghan, A., Glazer, N. L., Morrison, A. C., Johnson, A. D., Aspelund, T., et al. (2009) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,364

Evolving importance of kidney disease: from subspecialty to global health burden

Eckardt, K.-U., Coresh, J., Devuyst, O., Johnson, R. J., Köttgen, A., Levey, A. S., & Levin, A. (2013) · The Lancet

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 1,159

Human metabolic individuality in biomedical and pharmaceutical research

CARDIoGRAM, Suhre, K., Shin, S.-Y., Petersen, A.-K., Mohney, R. P., Meredith, D., Wägele, B., Altmaier, E., Deloukas, P., Erdmann, J., et al. (2011) · Nature

Genetic Associations and EpidemiologyMetabolomics and Mass Spectrometry Studies

Cited by 1,017

A saturated map of common genetic variants associated with human height

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., et al. (2022) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 825

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

Common variants in KCNN3 are associated with lone atrial fibrillation

Ellinor, P. T., Lunetta, K. L., Glazer, N. L., Pfeufer, A., Alonso, A., Chung, M. K., Sinner, M. F., de Bakker, P. I. W., Mueller, M., Lubitz, S. A., et al. (2010) · Nature Genetics

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 485

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 442

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

Benjamin, E. J., Rice, K. M., Arking, D. E., Pfeufer, A., van Noord, C., Smith, A. V., Schnabel, R. B., Bis, J. C., Boerwinkle, E., Sinner, M. F., et al. (2009) · Nature Genetics

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 390

Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies

Zhang, J., Dutta, D., Köttgen, A., Tin, A., Schlosser, P., Grams, M. E., Harvey, B., CKDGen Consortium, Yu, B., Boerwinkle, E., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 373

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., et al. (2018) · Nature Communications

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 280

A metabolome-wide association study of kidney function and disease in the general population

Sekula, P., Goek, O.-N., Quaye, L., Barrios, C., Levey, A. S., Römisch-Margl, W., Menni, C., Yet, I., Gieger, C., Inker, L. A., et al. (2016) · Journal of the American Society of Nephrology

Metabolomics and Mass Spectrometry StudiesChronic Kidney Disease and Diabetes

Cited by 203

Metabolites associate with kidney function decline and incident chronic kidney disease in the general population

Goek, O.-N., Prehn, C., Sekula, P., Römisch-Margl, W., Döring, A., Gieger, C., Heier, M., Koenig, W., Wang-Sattler, R., Illig, T., et al. (2013) · Nephrology Dialysis Transplantation

Metabolomics and Mass Spectrometry StudiesChronic Kidney Disease and Diabetes

Cited by 143

A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure

Yu, Z., Coresh, J., Qi, G., Grams, M., Boerwinkle, E., Snieder, H., Teumer, A., Pattaro, C., Köttgen, A., Chatterjee, N., et al. (2020) · Kidney International

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 135

Serum Metabolite Concentrations and Decreased GFR in the General Population

Goek, O.-N., Döring, A., Gieger, C., Heier, M., Koenig, W., Prehn, C., Römisch-Margl, W., Wang-Sattler, R., Illig, T., Suhre, K., et al. (2012) · American Journal of Kidney Diseases

Metabolomics and Mass Spectrometry StudiesChronic Kidney Disease and Diabetes

Cited by 121

A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction

Coassin, S., Erhart, G., Weissensteiner, H., Eca Guimarães de Araújo, M., Lamina, C., Schönherr, S., Forer, L., Haun, M., Losso, J. L., Köttgen, A., et al. (2017) · European Heart Journal

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 93

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations

Schultheiss, U. T., Teumer, A., Medici, M., Li, Y., Daya, N., Chaker, L., Homuth, G., Uitterlinden, A. G., Nauck, M., Hofman, A., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 50

The DNA methylome in panic disorder: A case-control and longitudinal psychotherapy-epigenetic study

Ziegler, C., Grundner-Culemann, F., Schiele, M. A., Schlosser, P., Kollert, L., Mahr, M., Gajewska, A., Lesch, K.-P., Deckert, J., Köttgen, A., et al. (2019) · Translational Psychiatry

Epigenetics and DNA MethylationAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 47

Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism

Cheng, Y., Schlosser, P., Hertel, J., Sekula, P., Oefner, P. J., Spiekerkoetter, U., Mielke, J., Freitag, D. F., Schmidts, M., GCKD Investigators, et al. (2021) · Nature Communications

Metabolism and Genetic DisordersGenomics and Rare Diseases

Cited by 37

Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases

Li, Y., Cheng, Y., Consolato, F., Schiano, G., Chong, M. R., Pietzner, M., Nguyen, N. Q. H., Scherer, N., Biggs, M. L., Kleber, M. E., et al. (2022) · JCI Insight

Genetic Associations and EpidemiologyRenal Diseases and Glomerulopathies

Cited by 22