Berger, Johannes

X-linked adrenoleukodystrophy: Clinical, metabolic, genetic and pathophysiological aspects

Kemp, S., Berger, J., & Aubourg, P. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 283

Pathophysiology of X-linked adrenoleukodystrophy

Berger, J., Forss-Petter, S., & Eichler, F. S. (2014) · Biochimie

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 238

Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling

Wiese, S., Gronemeyer, T., Ofman, R., Kunze, M., Grou, C. P., Almeida, J. A., Eisenacher, M., Stephan, C., Hayen, H., Schollenberger, L., et al. (2007) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsRedox biology and oxidative stress

Cited by 231

Peroxisomal alterations in Alzheimer’s disease

Kou, J., Kovacs, G. G., Höftberger, R., Kulik, W., Brodde, A., Forss-Petter, S., Hönigschnabl, S., Gleiss, A., Brügger, B., Wanders, R., et al. (2011) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 227

Peroxisomes in brain development and function

Berger, J., Dorninger, F., Forss-Petter, S., & Kunze, M. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 194

Dysferlin Is a New Marker for Leaky Brain Blood Vessels in Multiple Sclerosis

Hochmeister, S., Grundtner, R., Bauer, J., Engelhardt, B., Lyck, R., Gordon, G., Korosec, T., Kutzelnigg, A., Berger, J. J., Bradl, M., et al. (2006) · Journal of Neuropathology and Experimental Neurology

Multiple Sclerosis Research StudiesBarrier Structure and Function Studies

Cited by 160

Adrenoleukodystrophy-Related Protein Can Compensate Functionally for Adrenoleukodystrophy Protein Deficiency (X-ALD): Implications for Therapy

Netik, A., Forss-Petter, S., Holzinger, A., Molzer, B., Unterrainer, G., & Berger, J. (1999) · Human Molecular Genetics

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 148

Impaired Very Long-chain Acyl-CoA β-Oxidation in Human X-linked Adrenoleukodystrophy Fibroblasts Is a Direct Consequence of ABCD1 Transporter Dysfunction

Wiesinger, C., Kunze, M., Regelsberger, G., Forss-Petter, S., & Berger, J. (2013) · Journal of Biological Chemistry

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 145

The genetic landscape of X-linked adrenoleukodystrophy: inheritance, mutations, modifier genes, and diagnosis

Berger, J., Wiesinger, C., & Eichler, F. (2015) · The Application of Clinical Genetics

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 140

X-linked adrenoleukodystrophy (ALD): A novel mutation of the ALD gene in 6 members of a family presenting with 5 different phenotypes

Berger, J., Molzer, B., Fae, I., & Bernheimer, H. (1994) · Biochemical and Biophysical Research Communications

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 126

The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression

Berger, J., Albet, S., Bentejac, M., Netik, A., Holzinger, A., Roscher, A. A., Bugaut, M., & Forss‐Petter, S. (1999) · European Journal of Biochemistry

Metabolism and Genetic DisordersDrug Transport and Resistance Mechanisms

Cited by 106

cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter

Holzinger, A., Kammerer, S., Berger, J., & Roscher, A. A. (1997) · Biochemical and Biophysical Research Communications

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 92

Human leukocyte antigens and cytokine expression in cerebral inflammatory demyelinative lesions of X-linked adrenoleukodystrophy and multiple sclerosis

McGuinness, M. C., Powers, J. M., Bias, W. B., Schmeckpeper, B. J., Segal, A. H., Gowda, V. C., Wesselingh, S. L., Berger, J., Griffin, D. E., & Smith, K. D. (1997) · Journal of Neuroimmunology

Multiple Sclerosis Research StudiesLysosomal Storage Disorders Research

Cited by 89

Impaired plasticity of macrophages in X-linked adrenoleukodystrophy

Weinhofer, I., Zierfuss, B., Hametner, S., Wagner, M., Popitsch, N., Machacek, C., Bartolini, B., Zlabinger, G., Ohradanova-Repic, A., Stockinger, H., et al. (2018) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 72

Fibrate induction of the adrenoleukodystrophy‐related gene (ABCD2): Promoter analysis and role of the peroxisome proliferator‐activated receptor PPARα

Fourcade, S., Savary, S., Albet, S., Gauthé, D., Gondcaille, C., Pineau, T., Bellenger, J., Bentejac, M., Holzinger, A., Berger, J., et al. (2001) · European Journal of Biochemistry

Peroxisome Proliferator-Activated ReceptorsMetabolism and Genetic Disorders

Cited by 70

Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy

Höftberger, R., Kunze, M., Weinhofer, I., Aboul-Enein, F., Voigtländer, T., Oezen, I., Amann, G., Bernheimer, H., Budka, H., & Berger, J. (2007) · Neurobiology of Disease

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 69

X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism is severely impaired in monocytes but not in lymphocytes

Weber, F. D., Wiesinger, C., Forss-Petter, S., Regelsberger, G., Einwich, A., Weber, W. H. A., Kohler, W., Stockinger, H., & Berger, J. (2014) · Human Molecular Genetics

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 63

Impaired neurotransmission in ether lipid-deficient nerve terminals

Brodde, A., Teigler, A., Brugger, B., Lehmann, W. D., Wieland, F., Berger, J., & Just, W. W. (2012) · Human Molecular Genetics

Lipid metabolism and biosynthesisMetabolism and Genetic Disorders

Cited by 57

The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy

Rodríguez-Pascau, L., Vilalta, A., Cerrada, M., Traver, E., Forss-Petter, S., Weinhofer, I., Bauer, J., Kemp, S., Pina, G., Pascual, S., et al. (2021) · Science Translational Medicine

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 40

Mechanistic Insights into PTS2-mediated Peroxisomal Protein Import

Kunze, M., Malkani, N., Maurer-Stroh, S., Wiesinger, C., Schmid, J. A., & Berger, J. (2015) · Journal of Biological Chemistry

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 40

X-linked adrenoleukodystrophy phenotype is independent of ABCD2 genotype

Maier, E. M., Mayerhofer, P. U., Asheuer, M., Köhler, W., Rothe, M., Muntau, A. C., Roscher, A. A., Holzinger, A., Aubourg, P., & Berger, J. (2008) · Biochemical and Biophysical Research Communications

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 34

Abcd2 Is a Strong Modifier of the Metabolic Impairments in Peritoneal Macrophages of Abcd1-Deficient Mice

Muneer, Z., Wiesinger, C., Voigtländer, T., Werner, H. B., Berger, J., & Forss-Petter, S. (2014) · PLoS ONE

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 33

Eight novel ABCD1 gene mutations and three polymorphisms in patients with X-linked adrenoleukodystrophy: The first polymorphism causing an amino acid exchange

Dvoráková, L., Štorkánová, G., Unterrainer, G., Hujová, J., Kmoch, S., Zeman, J., Hrebícek, M., & Berger, J. (2001) · Human Mutation

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 23

Leriglitazone halts disease progression in adult patients with early cerebral adrenoleukodystrophy

Golse, M., Weinhofer, I., Blanco, B., Barbier, M., Yazbeck, E., Huiban, C., Chaumette, B., Pichon, B., Fatemi, A., Pascual, S., et al. (2024) · Brain

Lysosomal Storage Disorders ResearchMultiple Sclerosis Research Studies

Cited by 23