Impaired neurotransmission in ether lipid-deficient nerve terminals

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751 · see citing works

Signal integration in the endoplasmic reticulum unfolded protein response

Ron, D., & Walter, P. (2007) · Nature reviews. Molecular cell biology · doi:10.1038/nrm2199 · Cited by 6,499 · see citing works

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Walter, P., & Ron, D. (2011) · Science · doi:10.1126/science.1209038 · Cited by 5,893 · see citing works

Determination of protein: A modification of the lowry method that gives a linear photometric response

Hartree, E. F. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90094-2 · Cited by 5,542 · see citing works

Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots

Rouser, G., Fleischer, S., & Yamamoto, A. (1970) · Lipids · doi:10.1007/bf02531316 · Cited by 3,280 · see citing works

THE SYNAPTIC VESICLE CYCLE

Südhof, T. C. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131412 · Cited by 2,491 · see citing works

Membrane Fusion: Grappling with SNARE and SM Proteins

Südhof, T. C., & Rothman, J. E. (2009) · Science · doi:10.1126/science.1161748 · Cited by 2,027 · see citing works

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

Eggeling, C., Ringemann, C., Medda, R., Schwarzmann, G. O. H., Sandhoff, K., Polyakova, S. M., Belov, V. N., Hein, B., von Middendorff, C., Schönle, A., et al. (2008) · Nature · doi:10.1038/nature07596 · Cited by 1,521 · see citing works

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

Geppert, M., Goda, Y., Hammer, R. E., Li, C., Rosahl, T. W., Stevens, C. F., & Südhof, T. C. (1994) · Cell · doi:10.1016/0092-8674(94)90556-8 · Cited by 1,483 · see citing works

Theory of self-assembly of lipid bilayers and vesicles

Israelachvili, J. N., Mitchell, D. J., & Ninham, B. W. (1977) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(77)90099-2 · Cited by 961 · see citing works

Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry

Brügger, B., Erben, G., Sandhoff, R., Wieland, F., & Lehmann, W. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.6.2339 · Cited by 882 · see citing works

Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter

Bellocchio, E. E., Reimer, R. J., Fremeau, R. T., & Edwards, R. H. (2000) · Science · doi:10.1126/science.289.5481.957 · Cited by 795 · see citing works

SNAREs are concentrated in cholesterol‐dependent clusters that define docking and fusion sites for exocytosis

Lang, T., Bruns, D., Wenzel, D., Riedel, D., Holroyd, P., Thiele, C., & Jahn, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.9.2202 · Cited by 686 · see citing works

Plasmalogens: biosynthesis and functions

Nagan, N., & Zoeller, R. A. (2001) · Progress in Lipid Research · doi:10.1016/s0163-7827(01)00003-0 · Cited by 654 · see citing works

Lipid Mediators in Health and Disease: Enzymes and Receptors as Therapeutic Targets for the Regulation of Immunity and Inflammation

Shimizu, T. (2008) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.011008.145616 · Cited by 577 · see citing works

Lipid Rafts Are Enriched in Arachidonic Acid and Plasmenylethanolamine and Their Composition Is Independent of Caveolin-1 Expression: A Quantitative Electrospray Ionization/Mass Spectrometric Analysis

PIKE, L. J., Han, X., Chung, K.-N., & Gross, R. W. (2002) · Biochemistry · doi:10.1021/bi0156557 · Cited by 512 · see citing works

SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis

Chamberlain, L. H., Burgoyne, R. D., & Gould, G. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091502398 · Cited by 432 · see citing works

A methodology for analysis of tissue sulfhydryl components

Boyne, A. F., & Ellman, G. L. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90335-1 · Cited by 423 · see citing works

A rapid method for isolation of synaptosomes on Percoll gradients

Dunkley, P. R., Jarvie, P. E., Heath, J. W., Kidd, G. J., & Rostas, J. A. P. (1986) · Brain Research · doi:10.1016/0006-8993(86)91464-2 · Cited by 418 · see citing works

Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking

Lykkesfeldt, J. (2007) · Clinica Chimica Acta · doi:10.1016/j.cca.2007.01.028 · Cited by 416 · see citing works

Energetics of intermediates in membrane fusion: comparison of stalk and inverted micellar intermediate mechanisms

Siegel, D. P. (1993) · Biophysical Journal · doi:10.1016/s0006-3495(93)81256-6 · Cited by 399 · see citing works

The Neurotransmitter Cycle and Quantal Size

Edwards, R. H. (2007) · Neuron · doi:10.1016/j.neuron.2007.09.001 · Cited by 363 · see citing works

Evaluation of total antioxidant potential (TRAP) and total antioxidant reactivity from luminol-enhanced chemiluminescence measurements

Lissi, E. A., Salim-Hanna, M., Pascual, C., & del Castillo, M. D. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00117-3 · Cited by 362 · see citing works

A possible role for plasmalogens in protecting animal cells against photosensitized killing.

Zoeller, R. A., Morand, O. H., & Raetz, C. R. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)38000-1 · Cited by 348 · see citing works

Glycosylphosphatidylinositol (GPI)-Anchored Proteins.

Ikezawa, H. (2002) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.25.409 · Cited by 310 · see citing works

Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death

Apostolou, A., Shen, Y., Liang, Y., Luo, J., & Fang, S. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.05.001 · Cited by 288 · see citing works

Endocytosis: clathrin-mediated membrane budding.

Ungewickell, E., & Hinrichsen, L. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.05.003 · Cited by 257 · see citing works

The ether lipid-deficient mouse: Tracking down plasmalogen functions

Gorgas, K., Teigler, A., Komljenovic, D., & Just, W. W. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.08.038 · Cited by 231 · see citing works

Ca2+-dependent and Ca2+- independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: Possible relevance to hyoglycaemia and anoxia

Kauppinen, R. A., McMahon, H. T., & Nicholls, D. G. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90228-x · Cited by 229 · see citing works

Plasmenylethanolamine Facilitates Rapid Membrane Fusion: A Stopped-Flow Kinetic Investigation Correlating the Propensity of a Major Plasma Membrane Constituent to Adopt an HII Phase with Its Ability to Promote Membrane Fusion

Glaser, P. E. A., & Gross, R. W. (1994) · Biochemistry · doi:10.1021/bi00185a019 · Cited by 229 · see citing works

Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice

Rodemer, C., Thai, T.-P., Brügger, B., Kaercher, T., Werner, H. B., Nave, K., Wieland, F., Gorgas, K., & Just, W. W. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg191 · Cited by 225 · see citing works

Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders

Wanders, R. J. A., & Waterham, H. R. (2004) · Clinical Genetics · doi:10.1111/j.1399-0004.2004.00329.x · Cited by 220 · see citing works

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

Paradies, G., Petrosillo, G., Paradies, V., & Ruggiero, F. M. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2010.12.016 · Cited by 220 · see citing works

Mechanisms of Membrane Fusion

Zimmerberg, J. J., Vogel, S. S., & Chernomordik, L. (1993) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.bb.22.060193.002245 · Cited by 203 · see citing works

Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: implications for cell growth and adaptability

Brostrom, M. A., & Brostrom, C. O. (2003) · Cell Calcium · doi:10.1016/s0143-4160(03)00127-1 · Cited by 197 · see citing works

Plasmalogens: targets for oxidants and major lipophilic antioxidants

Engelmann, B. (2004) · Biochemical Society Transactions · doi:10.1042/bst0320147 · Cited by 187 · see citing works

Peroxyl radicals: Inductors of neurodegenerative and other inflammatory diseases. Their origin and how they transform cholesterol, phospholipids, plasmalogens, polyunsaturated fatty acids, sugars, and proteins into deleterious products

Spiteller, G. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.03.013 · Cited by 187 · see citing works

Local routes revisited: the space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of Held

Meinrenken, C. J., Borst, J. G. G., & Sakmann, B. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.032714 · Cited by 183 · see citing works

The protective role of plasmalogens in iron-induced lipid peroxidation

Sindelar, P. J., Guan, Z.-Z., Dallner, G., & Ernster, L. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00221-4 · Cited by 181 · see citing works

Binding order of substrates to the (sodium + potassium ion)-coupled L-glutamic acid transporter from rat brain

Kanner, B. I., & Bendahan, A. (1982) · Biochemistry · doi:10.1021/bi00267a044 · Cited by 179 · see citing works

Studies on ether phospholipids

Gassama‐Diagne, A., Fauvel, J., Record, M., Chap, H., & Douste‐Blazy, L. (1984) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(84)90324-2 · Cited by 177 · see citing works

Transmitter Glutamate Release from Isolated Nerve Terminals: Evidence for Biphasic Release and Triggering by Localized Ca2+

McMahon, H. T., & Nicholls, D. G. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb02566.x · Cited by 159 · see citing works

Glutamate forward and reverse transport: From molecular mechanism to transporter‐mediated release after ischemia

Grewer, C. T., Gameiro, A. M., Zhang, Z., Tao, Z., Braams, S., & Rauen, T. (2008) · IUBMB Life · doi:10.1002/iub.98 · Cited by 157 · see citing works

The Membrane Domains Occupied by Glycosylphosphatidylinositol-anchored Prion Protein and Thy-1 Differ in Lipid Composition

Brügger, B., Hay, C., Leibrecht, I., Mombelli, E., Jen, A., Wieland, F., & Morris, R. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310207200 · Cited by 154 · see citing works

Chemiluminescent determination of acetylcholine, and continuous detection of its release from torpedo electric organ synapses and synaptosomes

Israël, M., & Lesbats, B. (1981) · Neurochemistry International · doi:10.1016/0197-0186(81)90052-8 · Cited by 150 · see citing works

Synaptosomal bioenergetics

Kauppinen, R. A., & Nicholls, D. G. (1986) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1986.tb09733.x · Cited by 150 · see citing works

Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria

Kiebish, M. A., Han, X., Cheng, H., Lunceford, A. L., Clarke, C. F., Moon, H., Chuang, J. H., & Seyfried, T. N. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05383.x · Cited by 144 · see citing works

Bending membranes to the task: structural intermediates in bilayer fusion

Chernomordik, L., & Zimmerberg, J. J. (1995) · Current Opinion in Structural Biology · doi:10.1016/0959-440x(95)80041-7 · Cited by 138 · see citing works

Characterization of the Exocytotic Release of Glutamate from Guinea‐Pig Cerebral Cortical Synaptosomes

Sánchez‐Prieto, J., Sihra, T. S., & Nicholls, D. G. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb03394.x · Cited by 134 · see citing works

Complexin cross-links pre-fusion SNAREs into a zig-zag array: a structure-based model for complexin clamping

Kümmel, D., Krishnakumar, S. S., Radoff, D., Li, F., Giraudo, C., Pincet, F., Rothman, J., & Reinisch, K. (2011) · Nature Structural &Molecular Biology · doi:10.1038/nsmb.2101 · Cited by 133 · see citing works

Impaired membrane traffic in defective ether lipid biosynthesis

Thai, T.-P. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.2.127 · Cited by 127 · see citing works

Glutathione metabolism and oxidative stress in neurodegeneration

Dringen, R. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01651.x · Cited by 123 · see citing works

Structural remodeling of GPI anchors during biosynthesis and after attachment to proteins

Fujita, M., & Kinoshita, T. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.10.079 · Cited by 116 · see citing works

Formation and regulation of lipid microdomains in cell membranes: Theory, modeling, and speculation

Fan, J., Sammalkorpi, M., & Haataja, M. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.10.051 · Cited by 113 · see citing works

Human Immunodeficiency Virus Type 1 Nef Activates p21-Activated Kinase via Recruitment into Lipid Rafts

Krautkrämer, E., Giese, S. I., Gasteier, J. E., Muranyi, W., & Fackler, O. (2004) · Journal of Virology · doi:10.1128/jvi.78.8.4085-4097.2004 · Cited by 100 · see citing works

Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum

Teigler, A., Komljenovic, D., Draguhn, A., Gorgas, K., & Just, W. W. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp110 · Cited by 99 · see citing works

MRI of the brain and cervical spinal cord in rhizomelic chondrodysplasia punctata

Bams-Mengerink, A. M., Majoie, C. B. L. M., Duran, M., Wanders, R. J. A., Van Hove, J., Scheurer, C. D., Barth, P. G., & Poll-The, B. T. (2006) · Neurology · doi:10.1212/01.wnl.0000205594.34647.d0 · Cited by 97 · see citing works

CRELD2 is a novel endoplasmic reticulum stress-inducible gene

Oh‐hashi, K., Koga, H., Ikeda, S., Shimada, K., Hirata, Y., & Kiuchi, K. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.07.047 · Cited by 96 · see citing works

Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes

Gil, C., Soler-Jover, A., Blasi, J., & Aguilera, J. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.01.111 · Cited by 90 · see citing works

Plasmalogen degradation by oxidative stress: production and disappearance of specific fatty aldehydes and fatty α-hydroxyaldehydes

Ingrand, S. S., Favrelière, S., Fauconneau, B., Mauco, G., & Tallineau, C. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00720-1 · Cited by 78 · see citing works

New views of glutamate transporter structure and function: advances and challenges

Jiang, J., & Amara, S. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.07.019 · Cited by 78 · see citing works

Bioenergetics and Transmitter Release in the Isolated Nerve Terminal

Nicholls, D. G. (2003) · Neurochemical Research · doi:10.1023/a:1025653805029 · Cited by 71 · see citing works

Biological roles of sulfoglycolipids and pathophysiology of their deficiency

Honke, K., Zhang, Y., Cheng, X., Kotani, N., & Taniguchi, N. (2004) · Glycoconjugate Journal · doi:10.1023/b:glyc.0000043749.06556.3d · Cited by 71 · see citing works

Two Mechanisms of Synaptic Vesicle Recycling in Rat Brain Nerve Terminals

Cousin, M. A., & Robinson, P. J. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0751645.x · Cited by 66 · see citing works

Structure and Regulation of the V-ATPases

Inoué, T., Wang, Y., Jefferies, K. C., Qi, J., Hinton, A. M., & Forgac, M. D. (2005) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-005-9478-8 · Cited by 64 · see citing works

Studies on ether phospholipids

Tamer, A. E., Record, M., Fauvel, J., Chap, H., & Douste‐Blazy, L. (1984) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(84)90323-0 · Cited by 62 · see citing works

Disruption of blood-testis barrier dynamics in ether-lipid-deficient mice

Komljenovic, D., Sandhoff, R., Teigler, A., Heid, H., Just, W. W., & Gorgas, K. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0809-7 · Cited by 62 · see citing works

Fatty acid metabolism and cell proliferation: IV. Effect of prostanoid biosynthesis from endogenous fatty acid release with cyclosporin‐A

Lindsey, J. A., Morisaki, N., Stitts, J. M., Zager, R. A., & Cornwell, D. G. (1983) · Lipids · doi:10.1007/bf02535399 · Cited by 57 · see citing works

Fatty acid metabolism and cell proliferation. VII. Antioxidant effects of tocopherols and their quinones

Lindsey, J. A., Zhang, H., Kaseki, H., Morisaki, N., Sato, T., & Cornwell, D. G. (1985) · Lipids · doi:10.1007/bf02534247 · Cited by 39 · see citing works

Molecular genetics of peroxisomal disorders

Hugo, W. M. (2000) · Frontiers in bioscience · doi:10.2741/moser · Cited by 39 · see citing works

Peroxidation of arachidonate containing plasmenyl glycerophosphocholine: facile oxidation of esterified arachidonate at carbon-5

Khaselev, N., & Murphy, R. C. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00361-0 · Cited by 35 · see citing works

Neurotransmitter release at rapid synapses

Dunant, Y. (2000) · Biochimie · doi:10.1016/s0300-9084(00)00194-2 · Cited by 35 · see citing works

The selective activation of the cardiac sarcolemmal sodium‐calcium exchanger by plasmalogenic phosphatidic acid produced by phospholipase D

Hale, C. C., Ebeling, E. G., Hsu, F., & Ford, D. A. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00017-9 · Cited by 21 · see citing works

Endoplasmic reticulum stress response in murine kidney exposed to acute hypobaric hypoxia

Karar, J., Dolt, K. S., & Pasha, M. A. Q. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.06.019 · Cited by 20 · see citing works

Enhanced chemiluminescent assays for acetylcholine

Ternaux, J., & Chamoin, M. (1994) · Journal of Bioluminescence and Chemiluminescence · doi:10.1002/bio.1170090205 · Cited by 17 · see citing works

Targeted Disruption Of Ether Lipid Synthesis In Mice

Rodemer, C., Thai, T.-P., Brügger, B., Gorgas, K., & Just, W. W. (2003) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-9072-3_46 · Cited by 17 · see citing works

Molecular genetics of peroxisomal disorders

Moser, H. W. (2000) · Frontiers in bioscience · doi:10.2741/a512 · Cited by 13 · see citing works

Over‐expression of the Anti‐apoptotic Protein Bcl‐2 Affects Membrane Lipid Composition in HL‐60 Cells

Cantrel, C., Zachowski, A., & Geny, B. (2009) · Lipids · doi:10.1007/s11745-009-3292-8 · Cited by 5 · see citing works

Structural and functional roles of ether lipids

Dean, J. M., & Lodhi, I. J. (2017) · Protein & Cell · doi:10.1007/s13238-017-0423-5 · Cited by 682 · see citing works

The peroxisome: an update on mysteries 2.0

Islinger, M., Völkl, A., Fahimi, H. D., & Schrader, M. (2018) · Histochemistry and Cell Biology · doi:10.1007/s00418-018-1722-5 · Cited by 287 · see citing works

The peroxisome: an update on mysteries

Islinger, M., Grille, S., Fahimi, H. D., & Schrader, M. (2012) · Histochemistry and Cell Biology · doi:10.1007/s00418-012-0941-4 · Cited by 279 · see citing works

The physiological functions of human peroxisomes

Wanders, R. J. A., Baes, M., Ribeiro, D., Ferdinandusse, S., & Waterham, H. R. (2023) · Physiological Reviews · doi:10.1152/physrev.00051.2021 · Cited by 228 · see citing works

Peroxisomal metabolism and oxidative stress

Nordgren, M., & Fransen, M. (2013) · Biochimie · doi:10.1016/j.biochi.2013.07.026 · Cited by 201 · see citing works

Peroxisomes in brain development and function

Berger, J., Dorninger, F., Forss-Petter, S., & Kunze, M. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.12.005 · Cited by 194 · see citing works

Peroxisomal Dysfunction in Age-Related Diseases

Cipolla, C. M., & Lodhi, I. J. (2017) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2016.12.003 · Cited by 173 · see citing works

From peroxisomal disorders to common neurodegenerative diseases – the role of ether phospholipids in the nervous system

Dorninger, F., Forss‐Petter, S., & Berger, J. (2017) · FEBS Letters · doi:10.1002/1873-3468.12788 · Cited by 162 · see citing works

Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells

Wang, B., Veldhoven, P. P. V., Brees, C., Rubio, N., Nordgren, M., Apanasets, O., Kunze, M., Baes, M. I., Agostinis, P., & Fransen, M. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.08.173 · Cited by 141 · see citing works

Greasing the synaptic vesicle cycle by membrane lipids

Puchkov, D., & Haucke, V. (2013) · Trends in Cell Biology · doi:10.1016/j.tcb.2013.05.002 · Cited by 119 · see citing works

Novel Cellular Functions of Very Long Chain-Fatty Acids: Insight From ELOVL4 Mutations

Deák, F., Anderson, R. E., Fessler, J. L., & Sherry, D. M. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00428 · Cited by 110 · see citing works

Plasmalogen homeostasis – regulation of plasmalogen biosynthesis and its physiological consequence in mammals

Honsho, M., & Fujiki, Y. (2017) · FEBS Letters · doi:10.1002/1873-3468.12743 · Cited by 106 · see citing works

Homeostasis of phospholipids — The level of phosphatidylethanolamine tightly adapts to changes in ethanolamine plasmalogens

Dorninger, F., Brodde, A., Braverman, N., Moser, A. B., Just, W. W., Forss‐Petter, S., Brügger, B., & Berger, J. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.11.005 · Cited by 96 · see citing works

Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial function and calcium signaling

Jadiya, P., Garbincius, J. F., & Elrod, J. W. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01224-4 · Cited by 94 · see citing works

Disturbed neurotransmitter homeostasis in ether lipid deficiency

Dorninger, F., König, T., Scholze, P., Berger, M. L., Zeitler, G., Wiesinger, C., Gundacker, A., Pollak, D. D., Huck, S., Just, W. W., et al. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz040 · Cited by 90 · see citing works

Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration

Fourcade, S., Ferrer, I., & Pujol, A. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.041 · Cited by 77 · see citing works

Plasmalogen-Based Liquid Crystalline Multiphase Structures Involving Docosapentaenoyl Derivatives Inspired by Biological Cubic Membranes

Angelova, A., Angelov, B., Drechsler, M., Bizien, T., Gorshkova, Y. E., & Deng, Y. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.617984 · Cited by 66 · see citing works

Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice

Gu, J., Chen, L., Sun, R., Wang, J., Wang, J., Lin, Y., Lei, S., Zhang, Y., Lv, D., Jiang, F., et al. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.815320 · Cited by 65 · see citing works

Orphan enzymes in ether lipid metabolism

Watschinger, K., & Werner, E. R. (2012) · Biochimie · doi:10.1016/j.biochi.2012.06.027 · Cited by 60 · see citing works

Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata

Fallatah, W., Smith, T. M., Cui, W., Jayasinghe, D., Pietro, E. D., Ritchie, S. A., & Braverman, N. (2019) · Disease Models & Mechanisms · doi:10.1242/dmm.042499 · Cited by 43 · see citing works

Reduced muscle strength in ether lipid‐deficient mice is accompanied by altered development and function of the neuromuscular junction

Dorninger, F., Herbst, R., Kravić, B., Camurdanoglu, B. Z., Mačinković, I., Zeitler, G., Forss‐Petter, S., Strack, S., Khan, M. M., Waterham, H. R., et al. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14082 · Cited by 41 · see citing works

Ether Lipid Deficiency in Mice Produces a Complex Behavioral Phenotype Mimicking Aspects of Human Psychiatric Disorders

Dorninger, F., Gundacker, A., Zeitler, G., Pollak, D. D., & Berger, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163929 · Cited by 41 · see citing works

Distribution of ELOVL4 in the developing and adult mouse brain

Sherry, D. M., Hopiavuori, B. R., Stiles, M. A., Rahman, N. S., Ozan, K. G., Deak, F., Agbaga, M.-P., & Anderson, R. E. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00038 · Cited by 38 · see citing works

How Do Ethanolamine Plasmalogens Contribute to Order and Structure of Neurological Membranes?

West, A., Zoni, V., Teague, W. E., Leonard, A. N., Vanni, S., Gawrisch, K., Tristram‐Nagle, S., Sachs, J. N., & Klauda, J. B. (2020) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.9b08850 · Cited by 38 · see citing works

Milk fat globule membrane concentrate as a nutritional supplement prevents age-related cognitive decline in old rats: A lipidomic study of synaptosomes

Baliyan, S., Calvo, M. V., Piquera, D., Montero, O., Visioli, F., Venero, C., & Fontecha, J. (2022) · Food Research International · doi:10.1016/j.foodres.2022.112163 · Cited by 36 · see citing works

Ether Lipid-Mediated Antioxidant Defense in Alzheimer’s Disease

Jové, M., Mota‐Martorell, N., Òbis, È., Sol, J., Martin‐Garí, M., Ferrer, I., Portero‐Otín, M., & Pamplona, R. (2023) · Antioxidants · doi:10.3390/antiox12020293 · Cited by 37 · see citing works

Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau

Kling, M. A., Goodenowe, D. B., Senanayake, V. K., MahmoudianDehkordi, S., Arnold, M., Massaro, T., Baillie, R., Han, X., Leung, Y. Y., Saykin, A. J., et al. (2020) · Alzheimer s & Dementia · doi:10.1002/alz.12110 · Cited by 36 · see citing works

Plasmalogens and fatty alcohols in rhizomelic chondrodysplasia punctata and Sjogren-Larsson syndrome.

Malheiro, A. R., da Silva, T. F., & Brites, P. (2015) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-014-9795-3 · Cited by 33 · see citing works

Inherited disorders of complex lipid metabolism: A clinical review

Xiao, C., Rossignol, F., Vaz, F. M., & Ferreira, C. R. (2021) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12369 · Cited by 31 · see citing works

Roles of endogenous ether lipids and associated PUFAs in the regulation of ion channels and their relevance for disease

Fontaine, D., Figiel, S., Félix, R., Kouba, S., Fromont, G., Mahéo, K., Potier‐Cartereau, M., Chantôme, A., & Vandier, C. (2020) · Journal of Lipid Research · doi:10.1194/jlr.ra120000634 · Cited by 30 · see citing works

Structural Characterization and Quantitation of Ether-Linked Glycerophospholipids in Peroxisome Biogenesis Disorder Tissue by Ultraviolet Photodissociation Mass Spectrometry

Blevins, M. S., Shields, S. W. J., Cui, W., Fallatah, W., Moser, A. B., Braverman, N., & Brodbelt, J. S. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c01274 · Cited by 20 · see citing works

Peroxisomal Dysfunction and Oxidative Stress in Neurodegenerative Disease: A Bidirectional Crosstalk

Fransen, M., Revenco, I., Li, H., Costa, C. F., Lismont, C., & Veldhoven, P. P. V. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-60204-8_2 · Cited by 19 · see citing works

The synaptic lipidome in health and disease

Vallés, A. S., & Barrantes, F. J. (2022) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2022.184033 · Cited by 16 · see citing works

Impaired plasmalogen synthesis dysregulates liver X receptor-dependent transcription in cerebellum

Honsho, M., Dorninger, F., Abe, Y., Setoyama, D., Ohgi, R., Uchiumi, T., Kang, D., Berger, J., & Fujiki, Y. (2019) · The Journal of Biochemistry · doi:10.1093/jb/mvz043 · Cited by 16 · see citing works

Environmental Temperature Variation Affects Brain Lipid Composition in Adult Zebrafish (Danio rerio)

Maffioli, E., Nonnis, S., Negri, A. L., Fontana, M., Frabetti, F., Rossi, A. R., Tedeschi, G., & Toni, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179629 · Cited by 12 · see citing works

A Pex7 Deficient Mouse Series Correlates Biochemical and Neurobehavioral Markers to Genotype Severity—Implications for the Disease Spectrum of Rhizomelic Chondrodysplasia Punctata Type 1

Fallatah, W., Cui, W., Pietro, E. D., Carter, G. T., Pounder, B., Dorninger, F., Pifl, C., Moser, A. B., Berger, J., & Braverman, N. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.886316 · Cited by 12 · see citing works

The Effect of a Pex3 Mutation on Hearing and Lipid Content of the Inner Ear

Kochaj, R. M., Martelletti, E., Ingham, N. J., Buniello, A., Sousa, B. C., Wakelam, M. J. O., Lopez‐Clavijo, A. F., & Steel, K. P. (2022) · Cells · doi:10.3390/cells11203206 · Cited by 11 · see citing works

Dissecting Peroxisome-Mediated Signaling Pathways: A New and Exciting Research Field

Wang, B., Apanasets, O., Nordgren, M., & Fransen, M. (2014) · Springer eBooks · doi:10.1007/978-3-7091-1788-0_11 · Cited by 11 · see citing works

Influence of Myo-inositol Plus Ethanolamine on Plasmalogens and Cell Viability during Oxidative Stress

Sibomana, I., Grobe, N., DelRaso, N. J., & Reo, N. V. (2019) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.8b00280 · Cited by 9 · see citing works

AGMO Inhibitor Reduces 3T3-L1 Adipogenesis

Fischer, C., Wilken‐Schmitz, A., Hernández‐Olmos, V., Proschak, E., Stark, H., Fleming, I., Weigert, A., Thurn, M., Hofmann, M. C. J., Werner, E. R., et al. (2021) · Cells · doi:10.3390/cells10051081 · Cited by 8 · see citing works

Glycerophospholipid Analysis of Optic Nerve Regeneration Models Indicate Potential Membrane Order Changes Associated with the Lipidomic Shifts

Meehan, S. D., Neag, E. J., & Bhattacharya, S. K. (2023) · Journal of Ocular Pharmacology and Therapeutics · doi:10.1089/jop.2023.0003 · Cited by 7 · see citing works

A novel inducible animal model for studying chronic plasmalogen deficiency associated with Alzheimer’s disease

Smith, T. M., Knudsen, K. J., & Ritchie, S. A. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149132 · Cited by 7 · see citing works

Mouse Models to Study Peroxisomal Functions and Disorders: Overview, Caveats, and Recommendations

Kocherlakota, S., Swinkels, D., Veldhoven, P. P. V., & Baes, M. I. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3048-8_34 · Cited by 5 · see citing works

Plasmalogens in the Pathophysiology and Therapy of Age-Specific Diseases

Kytikovа, O. Y., Novgorodtseva, T. P., Antonyuk, M. V., & Gvozdenko, T. A. (2020) · Advances in Gerontology · doi:10.1134/s207905702003011x · Cited by 5 · see citing works

Xiaoyaosan modulates gut-brain metabolic pathways and brain microstructure in depression: a multi-omics insight

Hao, W., Sun, Y.-R., Zhang, Y.-R., Wang, R.-Y.-Q., Ning, W., Wang, L., Liu, D.-D., Li, Y., Huang, J., & Chen, J. (2025) · Chinese Medicine · doi:10.1186/s13020-025-01212-z · Cited by 4 · see citing works

Benchmarking of Trapped Ion Mobility Spectrometry in Differentiating Plasmalogens from Other Ether Lipids in Lipidomics Experiments

Koch, J. M., Neumann, L., Lackner, K., Fernández‐Quintero, M. L., Watschinger, K., & Keller, M. A. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.4c06617 · Cited by 4 · see citing works

The glycosomal alkyl-dihydroxyacetonephosphate synthase TbADS is essential for the synthesis of ether glycerophospholipids in procyclic trypanosomes

Lee, S., Kit, M. C. S., Williams, T. A., Yamout, N., & Zufferey, R. (2018) · Experimental Parasitology · doi:10.1016/j.exppara.2018.01.014 · Cited by 4 · see citing works

Homeostasis of Plasmalogens in Mammals

Honsho, M., & Fujiki, Y. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-100596-5.21664-8 · Cited by 4 · see citing works

Serum and urine metabolomics based on UPLC–QTOF/MS reveal the effect and potential mechanism of “schisandra–evodia” herb pair in the treatment of Alzheimer's disease

Pang, C., Wang, R., Liu, K., Xu, Y., Ni, J., Cao, Q., Chen, Y., Dong, P., & Han, H. (2024) · Biomedical Chromatography · doi:10.1002/bmc.5882 · Cited by 3 · see citing works

Peroxisomal ether-glycerophospholipid synthesis is dysregulated after TBI

Mehrabani-Tabari, A. A., Hegdekar, N., Bustos, S., Morel, Y., Ji, Y., Kachi, S. A., Pettyjohn-Robin, O., Thapa, S., Bhattiprolu, M., Lipinski, M. M., et al. (2025) · Journal of Lipid Research · doi:10.1016/j.jlr.2025.100821 · Cited by 2 · see citing works

Characterization of plasmalogen production in facultative anaerobic bacteria and aerobic synthesis in recombinant Escherichia coli expressing anaerobic bacterium-derived plasmalogen synthase genes

Irimajiri, R., Kuwabara, M., Ishibashi, Y., Ano, S., 藤野, 泰., Honsho, M., Fukami, K., Mawatari, S., Fujino, T., & Doi, K. (2025) · Applied and Environmental Microbiology · doi:10.1128/aem.00940-25 · Cited by 1 · see citing works

Determination of age-specific reference intervals for ethanolamine plasmalogen species in red blood cells using liquid chromatography tandem mass spectrometry

Biase, I. D., Miller, M., Zuromski, L. M., Anderson, K., Cole, S. L., Vachali, P. P., & Yuzyuk, T. N. (2026) · Clinica Chimica Acta · doi:10.1016/j.cca.2026.120993 · Cited by 1 · see citing works

Caractérisation des activités cytoprotectrices de molécules utilisées dans le traitement de la sclérose en plaques (diméthyle fumarate, monométhyle fumarate, biotine) sur des oligodendrocytes 158N : impact sur le stress oxydant, le statut mitochondrial, le statut lipidique, l’apoptose et l’autophagie

Sghaier, R. (2019) · theses.fr (ABES) · doi:10.70675/5d9752b6zd8dcz4044z9137zad307bac6dbd · Cited by 1 · see citing works

Apolipoprotein E and Mitochondria-associated Endoplasmic Reticulum Dysfunction

Tambini, M. D. (2016)

Trapped ion mobility spectrometry-guided molecular discrimination between plasmalogens and other ether lipids in lipidomics experimentsPreprint

Koch, J. M., Neumann, L., Lackner, K., Fernández‐Quintero, M. L., Watschinger, K., & Keller, M. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.23.619801

Syringa oblata Extract Regulates Oxidative Stress Through the BDNF/Nrf2/GPX4 Pathway and Improves Depressive Behavior in a Mouse Model

Zhai, S., Ye, R., Ruhan, A., Tuo, Y., Xiao, W., Liu, Y., Li, L., Sun, J., Feng, Y., & He, M. (2025) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-025-00700-5

L'interaction entre le canal calcique Orai3 et la protéine réticulaire STIM2 contribue à la prolifération et la survie des cellules cancéreuses prostatiques

Kouba, S. (2020) · theses.fr (ABES) · doi:10.70675/5b5af316z8676z4980zaa53zd235bf449fcb

Investigation of neurotransmitter release in brain slices of ether lipid-deficient mice

König, T. (2017)

Disturbed neurotransmitter homeostasis in ether lipid deficiency

Dorninger, F., König, T., Scholze, P., Berger, M. L., Zeitler, G., Wiesinger, C., Gundacker, A., Pollak, D. D., Huck, S., Just, W. W., et al. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz040 · Cited by 90 · see citing works

Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum

Teigler, A., Komljenovic, D., Draguhn, A., Gorgas, K., & Just, W. W. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp110 · Cited by 99 · see citing works

Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice

Rodemer, C., Thai, T.-P., Brügger, B., Kaercher, T., Werner, H. B., Nave, K., Wieland, F., Gorgas, K., & Just, W. W. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg191 · Cited by 225 · see citing works

Unstimulated and Exocytotic Glutamate Release from Cholesterol-Deficient Nerve Terminals

Borisova, Т. (2013) · SpringerBriefs in neuroscience · doi:10.1007/978-1-4614-7759-4_5