Habib, Naomi

Multiplex Genome Engineering Using CRISPR/Cas Systems

Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 15,339

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Konermann, S., Brigham, M. D., Trevino, A. E., Joung, J., Abudayyeh, O. O., Barcena, C., Hsu, P. D., Habib, N., Gootenberg, J. S., Nishimasu, H., et al. (2015) · Nature

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 2,825

Massively parallel single-nucleus RNA-seq with DroNc-seq

Habib, N., Avraham-Davidi, I., Basu, A., Burks, T., Shekhar, K., Hofree, M., Choudhury, S. R., Aguet, F., Gelfand, E., Ardlie, K., et al. (2017) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,069

DroNc-Seq: Deciphering cell types in human archived brain tissues by massively-parallel single nucleus RNA-seq

Habib, N., Basu, A., Avraham-Davidi, I., Burks, T., Choudhury, S. R., Aguet, F., Gelfand, E., Ardlie, K., Weitz, D. A., Rozenblatt-Rosen, O., et al. (2017) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,069

Disease-associated astrocytes in Alzheimer’s disease and aging

Habib, N., McCabe, C., Medina, S., Varshavsky, M., Kitsberg, D., Dvir-Szternfeld, R., Green, G., Dionne, D., Nguyen, L., Marshall, J. L., et al. (2020) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,009

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

Novershtern, N., Subramanian, A., Lawton, L. N., Mak, R. H., Haining, W. N., McConkey, M. E., Habib, N., Yosef, N., Chang, C. Y., Shay, T., et al. (2011) · Cell

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 942

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

Swiech, L., Heidenreich, M., Banerjee, A., Habib, N., Li, Y., Trombetta, J., Sur, M., & Zhang, F. (2015) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 772

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, M., Menon, V., Habib, N., Taga, M. F., Ma, Y., Yung, C. J., Cimpean, M., Khairallah, A., Coronas-Samano, G., Sankowski, R., et al. (2020) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 722

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons

Habib, N., Li, Y., Heidenreich, M., Swiech, L., Avraham-Davidi, I., Trombetta, J. J., Hession, C., Zhang, F., & Regev, A. (2016) · Science

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 601

Comparative functional genomics of the fission yeasts

Rhind, N., Chen, Z., Yassour, M., Thompson, D. A., Haas, B. J., Habib, N., Wapinski, I., Roy, S., Lin, M. F., Heiman, D. I., et al. (2011) · Science

Fungal and yeast genetics researchGenomics and Phylogenetic Studies

Cited by 484

A cellular and spatial map of the choroid plexus across brain ventricles and ages

Dani, N., Herbst, R. H., McCabe, C., Green, G. S., Kaiser, K., Head, J. P., Cui, J., Shipley, F. B., Jang, A., Dionne, D., et al. (2021) · Cell

Single-cell and spatial transcriptomicsCerebrospinal fluid and hydrocephalus

Cited by 388

Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease

Green, G. S., Fujita, M., Yang, H.-S., Taga, M., Cain, A., McCabe, C., Comandante-Lou, N., White, C. C., Schmidtner, A. K., Zeng, L., et al. (2024) · Nature

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 204

Multi-cellular communities are perturbed in the aging human brain and Alzheimer’s disease

Cain, A., Taga, M., McCabe, C., Green, G., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2020) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 143

Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease

Cain, A., Taga, M., McCabe, C., Green, G. S., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2023) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 142

Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety

Webster, A. N., Becker, J. J., Li, C., Schwalbe, D. C., Kerspern, D., Karolczak, E. O., Bundon, C., Onoharigho, R. A., Crook, M., Jalil, M., et al. (2023) · Nature Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 56

Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease

Green, G. S., Fujita, M., Yang, H.-S., Taga, M., McCabe, C., Cain, A., White, C. C., Schmidtner, A. K., Zeng, L., Wang, Y., et al. (2023) · Alzheimer s & Dementia

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 51

Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease

Green, G. S., Yang, H., Fujita, M., Taga, M., Regev, A., Menon, V., Bennett, D. A. A., Habib, N., & De Jager, P. L. (2023) · Alzheimer's & Dementia

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 51

A functional selection model explains evolutionary robustness despite plasticity in regulatory networks

Habib, N., Wapinski, I., Margalit, H., Regev, A., & Friedman, N. (2012) · Molecular Systems Biology

Fungal and yeast genetics researchGene Regulatory Network Analysis

Cited by 50

Cell-subtype specific effects of genetic variation in the aging and Alzheimer cortex

Fujita, M., Gao, Z., Zeng, L., McCabe, C., White, C. C., Ng, B., Green, G. S., Rozenblatt-Rosen, O., Phillips, D., Amir-Zilberstein, L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Genetic Associations and EpidemiologySingle-cell and spatial transcriptomics

Cited by 36

Early neuronal reprogramming and cell cycle reentry shape Alzheimer’s disease progression

Meir, R., Schwartz, G., Adam, M., Lapidot, A. A., Cain, A., Green, G. S., Menon, V., Bennett, D. A., De Jager, P. L., & Habib, N. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 3