Simonsen, Anne

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Molecular definitions of autophagy and related processes

Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Colombo, M. I., et al. (2017) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,646

Autophagy in major human diseases

Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cadwell, K., Cecconi, F., Choi, A. M. K., et al. (2021) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,585

Autophagy in healthy aging and disease

Aman, Y., Schmauck-Medina, T., Hansen, M., Morimoto, R. I., Simon, A. K., Bjedov, I., Palikaras, K., Simonsen, A., Johansen, T., Tavernarakis, N., et al. (2021) · Nature Aging

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 1,313

Autophagy in malignant transformation and cancer progression

Galluzzi, L., Pietrocola, F., Bravo‐San Pedro, J. M., Amaravadi, R. K., Baehrecke, E. H., Cecconi, F., Codogno, P., Debnath, J., Gewirtz, D. A., Karantza, V., et al. (2015) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,182

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J.-M., Brech, A., Callaghan, J., Toh, B.-H., Murphy, C., Zerial, M., & Stenmark, H. (1998) · Nature

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,133

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

Simonsen, A., Cumming, R. C., Brech, A., Isakson, P., Schubert, D. R., & Finley, K. D. (2008) · Autophagy

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 716

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

Filimonenko, M., Stuffers, S., Raiborg, C., Yamamoto, A., Malerød, L., Fisher, E. M. C., Isaacs, A., Brech, A., Stenmark, H., & Simonsen, A. (2007) · The Journal of Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 626

FYVE fingers bind PtdIns(3)P

Gaullier, J.-M., Simonsen, A., D'Arrigo, A., Bremnes, B., Stenmark, H., & Aasland, R. (1998) · Nature

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 553

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

Nezis, I. P., Simonsen, A., Sagona, A. P., Finley, K., Gaumer, S., Contamine, D., Rusten, T. E., Stenmark, H., & Brech, A. (2008) · The Journal of Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 370

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects

Bartlett, B. J., Isakson, P., Lewerenz, J., Sanchez, H., Kotzebue, R. W., Cumming, R. C., Harris, G. L., Nezis, I. P., Schubert, D. R., Simonsen, A., et al. (2011) · Autophagy

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 215

ESCRT-mediated phagophore sealing during mitophagy

Zhen, Y., Spangenberg, H., Munson, M. J., Brech, A., Schink, K. O., Tan, K.-W., Sørensen, V., Wenzel, E. M., Radulovic, M., Engedal, N., et al. (2020) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 209

Modulation of intracellular calcium homeostasis blocks autophagosome formation

Engedal, N., Torgersen, M. L., Guldvik, I. J., Barfeld, S. J., Bakula, D., Sætre, F., Hagen, L. K., Patterson, J. B., Proikas-Cezanne, T., Seglen, P. O., et al. (2013) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 104

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Mamińska, A., Bartosik, A., Banach-Orłowska, M., Pilecka, I., Jastrzębski, K., Zdżalik-Bielecka, D., Castanon, I., Poulain, M., Neyen, C., Wolińska-Nizioł, L., et al. (2016) · Science Signaling

NF-κB Signaling PathwaysCellular transport and secretion

Cited by 74

Genetic Modifiers of the Drosophila Blue Cheese Gene Link Defects in Lysosomal Transport With Decreased Life Span and Altered Ubiquitinated-Protein Profiles

Simonsen, A., Cumming, R. C., Lindmo, K., Galaviz, V., Cheng, S., Rusten, T. E., & Finley, K. D. (2007) · Genetics

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 67

Linking Lysosomal Trafficking Defects with Changes in Aging and Stress Response in Drosophila

Simonsen, A., Cumming, R. C., & Finley, K. D. (2007) · Autophagy

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 37

SNX10 functions as a modulator of piecemeal mitophagy and mitochondrial bioenergetics

Trachsel-Moncho, L., Veroni, C., Mathai, B. J., Lapao, A., Singh, S., Asp, N. T., Schultz, S. W., Pankiv, S., & Simonsen, A. (2025) · Journal of Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 16

SNX10 functions as a modulator of piecemeal mitophagy and mitochondrial bioenergetics

Trachsel-Moncho, L., Veroni, C., Mathai, B. J., Lapao, A., Singh, S., Asp, N. T., Schultz, S. W., Pankiv, S., & Simonsen, A. (2024) · The Journal of Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 16