Kubes, Paul

Neutrophil recruitment and function in health and inflammation

Kolaczkowska, E., & Kubes, P. (2013) · Nature Reviews Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 5,472

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Clark, S. R., Ma, A. C., Tavener, S. A., McDonald, B., Goodarzi, Z., Kelly, M. M., Patel, K. D., Chakrabarti, S., McAvoy, E., Sinclair, G. D., et al. (2007) · Nature Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 2,309

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

Cools-Lartigue, J., Spicer, J., McDonald, B., Gowing, S., Chow, S., Giannias, B., Bourdeau, F., Kubes, P., & Ferri, L. (2013) · Journal of Clinical Investigation

Neutrophil, Myeloperoxidase and Oxidative MechanismsCancer, Stress, Anesthesia, and Immune Response

Cited by 1,395

An emerging role for neutrophil extracellular traps in noninfectious disease

Jorch, S. K., & Kubes, P. (2017) · Nature Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsAutoimmune and Inflammatory Disorders

Cited by 1,244

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

McDonald, B., Pittman, K., Menezes, G. B., Hirota, S. A., Slaba, I., Waterhouse, C. C. M., Beck, P. L., Muruve, D. A., & Kubes, P. (2010) · Science

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 1,210

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

Yipp, B. G., Petri, B., Salina, D., Jenne, C. N., Scott, B. N. V., Zbytnuik, L. D., Pittman, K., Asaduzzaman, M., Wu, K., Meijndert, H. C., et al. (2012) · Nature Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsAntimicrobial Peptides and Activities

Cited by 1,169

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

Pilsczek, F. H., Salina, D., Poon, K. K. H., Fahey, C., Yipp, B. G., Sibley, C. D., Robbins, S. M., Green, F. H. Y., Surette, M. G., Sugai, M., et al. (2010) · The Journal of Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsAntimicrobial Peptides and Activities

Cited by 1,114

Immune surveillance by the liver

Jenne, C. N., & Kubes, P. (2013) · Nature Immunology

Liver physiology and pathologyImmune Response and Inflammation

Cited by 1,047

Immune Responses in the Liver

Kubes, P., & Jenne, C. (2018) · Annual Review of Immunology

Liver physiology and pathologyImmune Response and Inflammation

Cited by 923

Neutrophils and NETS in modulating acute and chronic inflammation

Castanheira, F. V. S., & Kubes, P. (2019) · Blood

Neutrophil, Myeloperoxidase and Oxidative MechanismsBlood disorders and treatments

Cited by 792

Sterile inflammation in the liver

Kubes, P., & Mehal, W. Z. (2012) · Gastroenterology

Immune Response and InflammationInflammasome and immune disorders

Cited by 666

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

Kolaczkowska, E., Jenne, C. N., Surewaard, B. G. J., Thanabalasuriar, A., Lee, W.-Y., Sanz, M.-J., Mowen, K., Opdenakker, G., & Kubes, P. (2015) · Nature Communications

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 584

Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease – novel insights into cellular communication circuits

Peiseler, M., Schwabe, R., Hampe, J., Kubes, P., Heikenwälder, M., & Tacke, F. (2022) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 564

A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade Visceral Organs to Affect Tissue Repair

Wang, J., & Kubes, P. (2016) · Cell

Immune cells in cancerWound Healing and Treatments

Cited by 537

More friend than foe: the emerging role of neutrophils in tissue repair

Peiseler, M., & Kubes, P. (2019) · Journal of Clinical Investigation

Neutrophil, Myeloperoxidase and Oxidative MechanismsWound Healing and Treatments

Cited by 423

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Malehmir, M., Pfister, D., Gallage, S., Szydlowska, M., Inverso, D., Kotsiliti, E., Leone, V., Peiseler, M., Surewaard, B. G. J., Rath, D., et al. (2019) · Nature Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 398

Intravascular immunity: the host–pathogen encounter in blood vessels

Hickey, M. J., & Kubes, P. (2009) · Nature Reviews Immunology

Immune Response and InflammationInvertebrate Immune Response Mechanisms

Cited by 251

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D. A., Yaqoob, U., et al. (2019) · Gastroenterology

Liver physiology and pathologyLiver Disease and Transplantation

Cited by 240

CRIg Functions as a Macrophage Pattern Recognition Receptor to Directly Bind and Capture Blood-Borne Gram-Positive Bacteria

Zeng, Z., Surewaard, B. G. J., Wong, C. H. Y., Geoghegan, J. A., Jenne, C. N., & Kubes, P. (2016) · Cell Host & Microbe

Complement system in diseasesImmune Response and Inflammation

Cited by 229

Inhaled NO as a viable antiadhesive therapy for ischemia/reperfusion injury of distal microvascular beds.

Fox-Robichaud, A., Payne, D., Hasan, S. U., Ostrovsky, L., Fairhead, T., Reinhardt, P., & Kubes, P. (1998) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsCell Adhesion Molecules Research

Cited by 227

Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity

Fowler, B. J., Gelfand, B. D., Kim, Y., Kerur, N., Tarallo, V., Hirano, Y., Amarnath, S., Fowler, D. H., Radwan, M., Young, M. T., et al. (2014) · Science

Inflammasome and immune disordersAdenosine and Purinergic Signaling

Cited by 225

Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain

Shi, M., Li, S. S., Zheng, C., Jones, G. J., Kim, K. S., Zhou, H., Kubes, P., & Mody, C. H. (2010) · Journal of Clinical Investigation

Fungal Infections and StudiesBacterial Infections and Vaccines

Cited by 222

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

Huang, L.-R., Wohlleber, D., Reisinger, F., Jenne, C. N., Cheng, R.-L., Abdullah, Z., Schildberg, F. A., Odenthal, M., Dienes, H.-P., van Rooijen, N., et al. (2013) · Nature Immunology

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 216

Essential Role for Neutrophil Recruitment to the Liver in Concanavalin A-Induced Hepatitis

Bonder, C. S., Ajuebor, M. N., Zbytnuik, L. D., Kubes, P., & Swain, M. G. (2004) · The Journal of Immunology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 192