Loeser, Richard F.

Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: The arthritis, diet, and activity promotion trial

Messier, S. P., Loeser, R. F., Miller, G. D., Morgan, T. M., Rejeski, W. J., Sevick, M. A., Ettinger, W. H., Pahor, M., & Williamson, J. D. (2004) · Arthritis & Rheumatism

Osteoarthritis Treatment and MechanismsMusculoskeletal pain and rehabilitation

Cited by 1,065

Effects of Intensive Diet and Exercise on Knee Joint Loads, Inflammation, and Clinical Outcomes Among Overweight and Obese Adults With Knee Osteoarthritis: The IDEA Randomized Clinical Trial

Messier, S. P., Mihalko, S. L., Legault, C., Miller, G. D., Nicklas, B. J., DeVita, P., Beavers, D. P., Hunter, D. J., Lyles, M. F., Eckstein, F., et al. (2013) · JAMA

Osteoarthritis Treatment and MechanismsMusculoskeletal pain and rehabilitation

Cited by 873

Mechanisms and therapeutic implications of cellular senescence in osteoarthritis

Coryell, P. R., Diekman, B. O., & Loeser, R. F. (2021) · Nature Reviews Rheumatology

Osteoarthritis Treatment and MechanismsTelomeres, Telomerase, and Senescence

Cited by 761

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

Loeser, R. F. (2009) · Osteoarthritis and Cartilage

Osteoarthritis Treatment and MechanismsTelomeres, Telomerase, and Senescence

Cited by 726

Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial

Nicklas, B. J., Ambrosius, W., Messier, S. P., Miller, G. D., Penninx, B. W., Loeser, R. F., Palla, S., Bleecker, E., & Pahor, M. (2004) · The American Journal of Clinical Nutrition

Adipokines, Inflammation, and Metabolic DiseasesExercise and Physiological Responses

Cited by 443

Microarray analysis reveals age‐related differences in gene expression during the development of osteoarthritis in mice

Loeser, R. F., Olex, A. L., McNulty, M. A., Carlson, C. S., Callahan, M. F., Ferguson, C. M., Chou, J., Leng, X., & Fetrow, J. S. (2012) · Arthritis & Rheumatism

Osteoarthritis Treatment and MechanismsHip disorders and treatments

Cited by 222

Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis

Diekman, B. O., Sessions, G. A., Collins, J. A., Knecht, A. K., Strum, S. L., Mitin, N. K., Carlson, C. S., Loeser, R. F., & Sharpless, N. E. (2018) · Aging Cell

Telomeres, Telomerase, and SenescenceOsteoarthritis Treatment and Mechanisms

Cited by 158

High fat-diet and saturated fatty acid palmitate inhibits IGF-1 function in chondrocytes

Nazli, S. A., Loeser, R. F., Chubinskaya, S., Willey, J. S., & Yammani, R. R. (2017) · Osteoarthritis and Cartilage

Osteoarthritis Treatment and MechanismsProteoglycans and glycosaminoglycans research

Cited by 43

A mouse model for chronic pain-induced increase in ethanol consumption

Butler, R. K., Knapp, D. J., Ulici, V., Longobardi, L., Loeser, R. F., & Breese, G. R. (2017) · Pain

Pain Mechanisms and TreatmentsAlcohol Consumption and Health Effects

Cited by 20

Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types

Sauty, S. M., Shine, J., Bostan, H., Li, J.-L., Mieczkowski, P. A., Loeser, R. F., Diekman, B. O., & Gordenin, D. A. (2026) · PLOS Genetics

Osteoarthritis Treatment and MechanismsDNA Repair Mechanisms

Cited by 0

Comparative whole-genome analyses of articular chondrocytes and skin fibroblasts reveal distinct genome instability landscapes in mesenchymal cell types

Sauty, S. M., Shine, J., Bostan, H., Li, J.-L., Mieczkowski, P. A., Loeser, R. F., Diekman, B. O., & Gordenin, D. A. (2026) · PLoS Genetics

Osteoarthritis Treatment and MechanismsDNA Repair Mechanisms

Cited by 0