Ren, Bing

The 4D nucleome project

the 4D Nucleome Network, Dekker, J., Belmont, A. S., Guttman, M., Leshyk, V. O., Lis, J. T., Lomvardas, S., Mirny, L. A., O’Shea, C. C., Park, P. J., et al. (2017) · Nature

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 732

Brain cell type–specific enhancer–promoter interactome maps and disease - risk association

Nott, A., Holtman, I. R., Coufal, N. G., Schlachetzki, J. C. M., Yu, M., Hu, R., Han, C. Z., Pena, M., Xiao, J., Wu, Y., et al. (2019) · Science

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 699

Human body epigenome maps reveal noncanonical DNA methylation variation

Schultz, M. D., He, Y., Whitaker, J. W., Hariharan, M., Mukamel, E. A., Leung, D., Rajagopal, N., Nery, J. R., Urich, M. A., Chen, H., et al. (2015) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 690

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

Hon, G. C., Hawkins, R. D., Caballero, O. L., Lo, C., Lister, R., Pelizzola, M., Valsesia, A., Ye, Z., Kuan, S., Edsall, L. E., et al. (2012) · Genome Research

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 583

Mapping Human Epigenomes

Rivera, C. M., & Ren, B. (2013) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 550

Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome

Xie, W., Barr, C. L., Kim, A., Yue, F., Lee, A. Y., Eubanks, J., Dempster, E. L., & Ren, B. (2012) · Cell

Genetic Syndromes and ImprintingEpigenetics and DNA Methylation

Cited by 543

Genomic encoding of transcriptional burst kinetics

Larsson, A. J. M., Johnsson, P., Hagemann-Jensen, M., Hartmanis, L., Faridani, O. R., Reinius, B., Segerstolpe, Å., Rivera, C. M., Ren, B., & Sandberg, R. (2019) · Nature

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 534

A multimodal cell census and atlas of the mammalian primary motor cortex

BRAIN Initiative Cell Census Network (BICCN), BRAIN Initiative Cell Census Network (BICCN) Corresponding authors, Callaway, E. M., Dong, H.-W., Ecker, J. R., Hawrylycz, M. J., Huang, Z. J., Lein, E. S., Ngai, J., Osten, P., et al. (2021) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 522

A single-cell atlas of chromatin accessibility in the human genome

Zhang, K., Hocker, J. D., Miller, M., Hou, X., Chiou, J., Poirion, O. B., Qiu, Y., Li, Y. E., Gaulton, K. J., Wang, A., et al. (2021) · Cell

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 502

Comprehensive analysis of single cell ATAC-seq data with SnapATAC

Fang, R., Preissl, S., Li, Y., Hou, X., Lucero, J., Wang, X., Motamedi, A., Shiau, A. K., Zhou, X., Xie, F., et al. (2021) · Nature Communications

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 455

An encyclopedia of mouse DNA elements (Mouse ENCODE)

Mouse ENCODE Consortium, Stamatoyannopoulos, J. A., Snyder, M., Hardison, R., Ren, B., Gingeras, T., Gilbert, D. M., Groudine, M., Bender, M., Kaul, R., et al. (2012) · Genome Biology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 446

A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex

Yao, Z., Liu, H., Xie, F., Fischer, S., Adkins, R. S., Aldridge, A. I., Ament, S. A., Bartlett, A., Behrens, M. M., Van den Berge, K., et al. (2021) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 398

An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types

Yao, Z., Liu, H., Xie, F., Fischer, S., Booeshaghi, A. S., Adkins, R. S., Aldridge, A. I., Ament, S. A., Pinto-Duarte, A., Bartlett, A., et al. (2020) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 397

The 3D genome in transcriptional regulation and pluripotency

Gorkin, D. U., Leung, D., & Ren, B. (2014) · Cell Stem Cell

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 391

Single-cell multimodal omics: the power of many

Zhu, C., Preissl, S., & Ren, B. (2020) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 386

RAP2 mediates mechanoresponses of the Hippo pathway

Meng, Z., Qiu, Y., Lin, K. C., Kumar, A., Placone, J. K., Fang, C., Wang, K.-C., Lu, S., Pan, M., Hong, A. W., et al. (2018) · Nature

Hippo pathway signaling and YAP/TAZCellular Mechanics and Interactions

Cited by 377

A compendium of promoter-centered long-range chromatin interactions in the human genome

Jung, I., Schmitt, A., Diao, Y., Lee, A. J., Liu, T., Yang, D., Tan, C., Eom, J., Chan, M., Chee, S., et al. (2019) · Nature Genetics

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 362

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

Li, Y., Reddy, M. A., Miao, F., Shanmugam, N., Yee, J.-K., Hawkins, D., Ren, B., & Natarajan, R. (2008) · Journal of Biological Chemistry

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 353

Mapping of long-range chromatin interactions by proximity ligation-assisted ChIP-seq

Fang, R., Yu, M., Li, G., Chee, S., Liu, T., Schmitt, A. D., & Ren, B. (2016) · Cell Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 344

Genome-wide mapping and analysis of chromosome architecture

Schmitt, A. D., Hu, M., & Ren, B. (2016) · Nature Reviews Molecular Cell Biology

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 344

An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome

Zhu, C., Yu, M., Huang, H., Juric, I., Abnousi, A., Hu, R., Lucero, J., Behrens, M. M., Hu, M., & Ren, B. (2019) · Nature Structural & Molecular Biology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 344

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

Liu, G.-H., Qu, J., Suzuki, K., Nivet, E., Li, M., Montserrat, N., Yi, F., Xu, X., Ruiz, S., Zhang, W., et al. (2012) · Nature

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 339

Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation

Preissl, S., Fang, R., Huang, H., Zhao, Y., Raviram, R., Gorkin, D. U., Zhang, Y., Sos, B. C., Afzal, V., Dickel, D. E., et al. (2018) · Nature Neuroscience

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 332

Joint profiling of histone modifications and transcriptome in single cells from mouse brain

Zhu, C., Zhang, Y., Li, Y. E., Lucero, J., Behrens, M. M., & Ren, B. (2021) · Nature Methods

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 301