Roussos, Panos

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., et al. (2022) · Biological Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 238

Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk

Rajarajan, P., Borrman, T., Liao, W., Schrode, N., Flaherty, E., Casiño, C., Powell, S., Yashaswini, C., LaMarca, E. A., Kassim, B., et al. (2018) · Science

Genomics and Chromatin DynamicsSchizophrenia research and treatment

Cited by 219

Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

Novikova, G., Kapoor, M., TCW, J., Abud, E. M., Efthymiou, A. G., Chen, S. X., Cheng, H., Fullard, J. F., Bendl, J., Liu, Y., et al. (2021) · Nature Communications

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 214

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease

Watson, C. T., Roussos, P., Garg, P., Ho, D. J., Azam, N., Katsel, P. L., Haroutunian, V., & Sharp, A. J. (2016) · Genome Medicine

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 201

Genetics of the human microglia regulome refines Alzheimer’s disease risk loci

Kosoy, R., Fullard, J. F., Zeng, B., Bendl, J., Dong, P., Rahman, S., Kleopoulos, S. P., Shao, Z., Girdhar, K., Humphrey, J., et al. (2022) · Nature Genetics

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 168

Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia

Bryois, J., Garrett, M. E., Song, L., Safi, A., Giusti-Rodriguez, P., Johnson, G. D., Shieh, A. W., Buil, A., Fullard, J. F., Roussos, P., et al. (2018) · Nature Communications

Schizophrenia research and treatmentGenomics and Chromatin Dynamics

Cited by 167

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome

Girdhar, K., Hoffman, G. E., Jiang, Y., Brown, L., Kundakovic, M., Hauberg, M. E., Francoeur, N. J., Wang, Y.-C., Shah, H., Kavanagh, D. H., et al. (2018) · Nature Neuroscience

Genomics and Chromatin DynamicsSchizophrenia research and treatment

Cited by 139

Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

Miller, M. L., Chadwick, B., Dickstein, D. L., Purushothaman, I., Egervari, G., Rahman, T., Tessereau, C., Hof, P. R., Roussos, P., Shen, L., et al. (2019) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 134

The triggering receptor expressed on myeloid cells 2 ( TREM2 ) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia

Roussos, P., Katsel, P., Fam, P., Tan, W., Purohit, D. P., & Haroutunian, V. (2015) · Alzheimer's & Dementia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 103

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Hu, B., Won, H., Mah, W., Park, R. B., Kassim, B., Spiess, K., Kozlenkov, A., Crowley, C. A., Pochareddy, S., The PsychENCODE Consortium, et al. (2021) · Nature Communications

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 103

Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia

Roussos, P. (2012) · Archives of General Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 93

A System-Level Transcriptomic Analysis of Schizophrenia Using Postmortem Brain Tissue Samples

Roussos, P., Katsel, P., Davis, K. L., Siever, L. J., & Haroutunian, V. (2012) · Archives of General Psychiatry

Schizophrenia research and treatmentBioinformatics and Genomic Networks

Cited by 92

Common risk variants identified in autism spectrum disorder

Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R., Won, H., Pallesen, J., Agerbo, E., Andreassen, O. A., Anney, R., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory)

Autism Spectrum Disorder ResearchGenetic Associations and Epidemiology

Cited by 89

Planning, decision-making and the COMT rs4818 polymorphism in healthy males

Roussos, P., Giakoumaki, S. G., Pavlakis, S., & Bitsios, P. (2008) · Neuropsychologia

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 85

Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition

Bharadwaj, R., Peter, C. J., Jiang, Y., Roussos, P., Vogel-Ciernia, A., Shen, E. Y., Mitchell, A. C., Mao, W., Whittle, C., Dincer, A., et al. (2014) · Neuron

Genomics and Chromatin DynamicsNeuroscience and Neuropharmacology Research

Cited by 84

Applications of artificial intelligence−machine learning for detection of stress: a critical overview

Mentis, A.-F. A., Lee, D., & Roussos, P. (2024) · Molecular Psychiatry

Emotion and Mood RecognitionArtificial Intelligence in Healthcare

Cited by 75

African ancestry GWAS of dementia in a large military cohort identifies significant risk loci

Sherva, R., Zhang, R., Sahelijo, N., Jun, G., Anglin, T., Chanfreau, C., Cho, K., Fonda, J. R., Gaziano, J. M., Harrington, K. M., et al. (2023) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 68

The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease

Bendl, J., Hauberg, M. E., Girdhar, K., Im, E., Vicari, J. M., Rahman, S., Fernando, M. B., Townsley, K. G., Dong, P., Misir, R., et al. (2022) · Nature Neuroscience

Genomics and Chromatin DynamicsAlzheimer's disease research and treatments

Cited by 65

DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype-phenotype prediction

Chandrashekar, P. B., Alatkar, S., Wang, J., Hoffman, G. E., He, C., Jin, T., Khullar, S., Bendl, J., Fullard, J. F., Roussos, P., et al. (2023) · Genome Medicine

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 37

Integration of Alzheimer’s disease genetics and myeloid genomics reveals novel disease risk mechanisms

Novikova, G., Kapoor, M., TCW, J., Abud, E. M., Efthymiou, A. G., Cheng, H., Fullard, J. F., Bendl, J., Roussos, P., Poon, W. W., et al. (2019) · Alzheimer s & Dementia

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 27

Single-cell atlas of transcriptomic vulnerability across multiple neurodegenerative and neuropsychiatric diseases

Lee, D., Koutrouli, M., Masse, N. Y., Hoffman, G. E., Kinrot, S., Wang, X., N.M., P., Pjanic, M., Clarence, T., Tsetsos, F., et al. (2024) · Alzheimer s & Dementia

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 26

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment

Trampush, J. W., Lencz, T., Knowles, E., Davies, G., Guha, S., Pe'er, I., Liewald, D. C., Starr, J. M., Djurovic, S., Melle, I., et al. (2015) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 24

NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure

Halene, T. B., Kozlenkov, A., Jiang, Y., Mitchell, A. C., Javidfar, B., Dincer, A., Park, R., Wiseman, J., Croxson, P. L., Giannaris, E. L., et al. (2016) · Schizophrenia Research

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 18

Evaluation of chromatin accessibility in prefrontal cortex of schizophrenia cases and controls

Bryois, J., Garrett, M. E., Song, L., Safi, A., Giusti-Rodriguez, P., Johnson, G. D., Demur, A. B., Fullard, J. F., Roussos, P., Sklar, P., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory)

Schizophrenia research and treatmentGenomics and Chromatin Dynamics

Cited by 7