Simen, Arthur A.

α2A-Adrenoceptors Strengthen Working Memory Networks by Inhibiting cAMP-HCN Channel Signaling in Prefrontal Cortex

Wang, M., Ramos, B. P., Paspalas, C. D., Shu, Y., Simen, A., Duque, A., Vijayraghavan, S., Brennan, A., Dudley, A., Nou, E., et al. (2007) · Cell

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

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A negative regulator of MAP kinase causes depressive behavior

Duric, V., Banasr, M., Licznerski, P., Schmidt, H. D., Stockmeier, C. A., Simen, A. A., Newton, S. S., & Duman, R. S. (2010) · Nature Medicine

Treatment of Major DepressionProtein Tyrosine Phosphatases

Cited by 412

Expression of CX 3 CR1 chemokine receptors on neurons and their role in neuronal survival

Meucci, O., Fatatis, A., Simen, A. A., & Miller, R. J. (2000) · Proceedings of the National Academy of Sciences

Chemokine receptors and signalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 385

Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry

Weder, N., Zhang, H., Jensen, K., Yang, B. Z., Simen, A., Jackowski, A., Lipschitz, D., Douglas-Palumberi, H., Ge, M., Perepletchikova, F., et al. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 324

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

Duric, V., Banasr, M., Stockmeier, C. A., Simen, A. A., Newton, S. S., Overholser, J. C., Jurjus, G. J., Dieter, L., & Duman, R. S. (2013) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 304

Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients

Laje, G., Lally, N., Mathews, D., Brutsche, N., Chemerinski, A., Akula, N., Kelmendi, B., Simen, A., McMahon, F. J., Sanacora, G., et al. (2012) · Biological Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 213

Maternal separation with early weaning: A novel mouse model of early life neglect

George, E. D., Bordner, K. A., Elwafi, H. M., & Simen, A. A. (2010) · BMC Neuroscience

Child Abuse and TraumaStress Responses and Cortisol

Cited by 163

cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex

Carlyle, B. C., Nairn, A. C., Wang, M., Yang, Y., Jin, L. E., Simen, A. A., Ramos, B. P., Bordner, K. A., Craft, G. E., Davies, P., et al. (2014) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 139

Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits

Carlyle, B. C., Duque, A., Kitchen, R. R., Bordner, K. A., Coman, D., Doolittle, E., Papademetris, X., Hyder, F., Taylor, J. R., & Simen, A. A. (2012) · Development and Psychopathology

Child Abuse and TraumaStress Responses and Cortisol

Cited by 80

Early life stress inhibits expression of a novel innate immune pathway in the developing hippocampus

Wei, L., Simen, A., Mane, S., & Kaffman, A. (2012) · Neuropsychopharmacology

Stress Responses and CortisolChild Abuse and Trauma

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Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction

Gamo, N. J., Duque, A., Paspalas, C. D., Kata, A., Fine, R., Boven, L., Bryan, C., Lo, T., Anighoro, K., Bermudez, L., et al. (2013) · Translational Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

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Disrupted in Schizophrenia 1 Modulates Medial Prefrontal Cortex Pyramidal Neuron Activity Through cAMP Regulation of Transient Receptor Potential C and Small-Conductance K+ Channels

El-Hassar, L., Simen, A. A., Duque, A., Patel, K. D., Kaczmarek, L. K., Arnsten, A. F. T., & Yeckel, M. F. (2014) · Biological Psychiatry

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 30

Neuroanatomical changes in a mouse model of early life neglect

Duque, A., Coman, D., Carlyle, B. C., Bordner, K. A., George, E. D., Papademetris, X., Hyder, F., & Simen, A. A. (2012) · Brain Structure and Function

Child Abuse and TraumaStress Responses and Cortisol

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