Patel, Dinshaw J.

Cyclic [G(2′,5′)pA(3′,5′)p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.

Gao, P., Ascano, M., Wu, Y., Barchet, W., Gaffney, B. L., Zillinger, T., Serganov, A. A., Liu, Y., Jones, R. A., Hartmann, G., et al. (2013) · Cell

interferon and immune responsesPhosphodiesterase function and regulation

Cited by 1,101

DNA methylation pathways and their crosstalk with histone methylation

Du, J., Johnson, L. M., Jacobsen, S. E., & Patel, D. J. (2015) · Nature Reviews Molecular Cell Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,000

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Kruidenier, L., Chung, C.-W., Cheng, Z., Liddle, J., Che, K., Joberty, G., Bantscheff, M., Bountra, C., Bridges, A., Diallo, H., et al. (2012) · Nature

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 950

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lama, L., Adura, C., Xie, W., Tomita, D., Kamei, T., Kuryavyi, V., Gogakos, T., Steinberg, J. I., Miller, M., Ramos-Espiritu, L., et al. (2019) · Nature Communications

interferon and immune responsesPhosphodiesterase function and regulation

Cited by 303

CONTRASTING STRUCTURAL IMPACTS INDUCED BY cis‐syn CYCLOBUTANE DIMER AND (6–4) ADDUCT IN DNA DUPLEX DECAMERS: IMPLICATION IN MUTAGENESIS AND REPAIR ACTIVITY

Kim, J., Patel, D., & Choi, B. (1995) · Photochemistry and Photobiology

DNA and Nucleic Acid ChemistryDNA Repair Mechanisms

Cited by 240

Phosphorylation of human Argonaute proteins affects small RNA binding

Rüdel, S., Wang, Y., Lenobel, R., Körner, R., Hsiao, H.-H., Urlaub, H., Patel, D., & Meister, G. (2011) · Nucleic Acids Research

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 188

Metabolite recognition principles and molecular mechanisms underlying riboswitch function

Serganov, A., & Patel, D. J. (2012) · Annual Review of Biophysics

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 160

Nuclear magnetic resonance studies of drug-nucleic acid interactions at the synthetic DNA level in solution

Patel, D. J. (1979) · Accounts of Chemical Research

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 147

c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry–related pockets

Ren, A., & Patel, D. J. (2014) · Nature Chemical Biology

RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology

Cited by 104

Amino acid recognition and gene regulation by riboswitches

Serganov, A., & Patel, D. J. (2009) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 69

Netropsin · dG‐dG‐dA‐dA‐dT‐dT‐dC‐dC Complex: Antibiotic Binding at Adenine · Thymine Base Pairs in the Minor Groove of the Self‐Complementary Octanucleotide Duplex

PATEL, D. J. (1979) · European Journal of Biochemistry

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 54

Cryo-EM structure of the Spo11 core complex bound to DNA

Yu, Y., Wang, J., Liu, K., Zheng, Z., Arter, M., Bouuaert, C. C., Pu, S., Patel, D. J., & Keeney, S. (2023) · Nature Structural & Molecular Biology

DNA Repair MechanismsEnzyme Structure and Function

Cited by 20

Cryo-EM structures of the Spo11 core complex bound to DNA

Yu, Y., Wang, J., Liu, K., Zheng, Z., Arter, M., Claeys Bouuaert, C., Pu, S., Patel, D. J., & Keeney, S. (2025) · Nature Structural & Molecular Biology

DNA Repair MechanismsEnzyme Structure and Function

Cited by 20