Gerhardt, Holger

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

Gerhardt, H., Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D., et al. (2003) · The Journal of Cell Biology

Angiogenesis and VEGF in CancerAxon Guidance and Neuronal Signaling

Cited by 2,894

Basic and Therapeutic Aspects of Angiogenesis

Potente, M., Gerhardt, H., & Carmeliet, P. (2011) · Cell

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 2,771

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

Hellström, M., Phng, L.-K., Hofmann, J. J., Wallgard, E., Coultas, L., Lindblom, P., Alva, J., Nilsson, A.-K., Karlsson, L., Gaiano, N., et al. (2007) · Nature

Angiogenesis and VEGF in CancerDevelopmental Biology and Gene Regulation

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Wnt/β-catenin signaling controls development of the blood–brain barrier

Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C. J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M., et al. (2008) · The Journal of Cell Biology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 860

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Schoors, S., Bruning, U., Missiaen, R., Queiroz, K. C. S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A. R., Christen, S., Goveia, J., et al. (2015) · Nature

Cancer, Lipids, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 646

FOXO1 couples metabolic activity and growth state in the vascular endothelium

Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M. F., Lim, R., Zimmermann, B., Aspalter, I. M., Franco, C. A., Boettger, T., et al. (2016) · Nature

FOXO transcription factor regulationAngiogenesis and VEGF in Cancer

Cited by 579

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

Jones, C. A., London, N. R., Chen, H., Park, K. W., Sauvaget, D., Stockton, R. A., Wythe, J. D., Suh, W., Larrieu-Lahargue, F., Mukouyama, Y.-S., et al. (2008) · Nature Medicine

Angiogenesis and VEGF in CancerAxon Guidance and Neuronal Signaling

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VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L., Heinolainen, K., Tvorogov, D., Zheng, W., Franco, C. A., Murtomäki, A., Aranda, E., et al. (2011) · Nature Cell Biology

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 321

A two-way communication between microglial cells and angiogenic sprouts regulates angiogenesis in aortic ring cultures

Rymo, S. F., Gerhardt, H., Wolfhagen Sand, F., Lang, R., Uv, A., & Betsholtz, C. (2011) · PLoS ONE

Angiogenesis and VEGF in CancerNeuroinflammation and Neurodegeneration Mechanisms

Cited by 235

Wiring the Vascular Network with Neural Cues: A CNS Perspective

Wälchli, T., Wacker, A., Frei, K., Regli, L., Schwab, M. E., Hoerstrup, S. P., Gerhardt, H., & Engelhardt, B. (2015) · Neuron

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 178

Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis

Stenzel, D., Lundkvist, A., Sauvaget, D., Busse, M., Graupera, M., van der Flier, A., Wijelath, E. S., Murray, J., Sobel, M., Costell, M., et al. (2011) · Development

Angiogenesis and VEGF in CancerAxon Guidance and Neuronal Signaling

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Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

Meyer, K., Kirchner, M., Uyar, B., Cheng, J.-Y., Russo, G., Hernandez-Miranda, L. R., Szymborska, A., Zauber, H., Rudolph, I.-M., Willnow, T. E., et al. (2018) · Cell

Protein Structure and DynamicsCellular transport and secretion

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Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes

Köhler, C., Nittner, D., Rambow, F., Radaelli, E., Stanchi, F., Vandamme, N., Baggiolini, A., Sommer, L., Berx, G., van den Oord, J. J., et al. (2017) · Cell Stem Cell

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

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Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

Vion, A.-C., Alt, S., Klaus-Bergmann, A., Szymborska, A., Zheng, T., Perovic, T., Hammoutene, A., Oliveira, M. B., Bartels-Klein, E., Hollfinger, I., et al. (2018) · Journal of Cell Biology

Genetic and Kidney Cyst DiseasesAngiogenesis and VEGF in Cancer

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Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Vion, A.-C., Perovic, T., Petit, C., Hollfinger, I., Bartels-Klein, E., Frampton, E., Gordon, E., Claesson-Welsh, L., & Gerhardt, H. (2021) · Frontiers in Physiology

Angiogenesis and VEGF in CancerCellular Mechanics and Interactions

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