Dantzer, Robert

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 7,395

Twenty years of research on cytokine-induced sickness behavior

Dantzer, R., & Kelley, K. W. (2007) · Brain, Behavior, and Immunity

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,420

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

O'Connor, J. C., Lawson, M. A., André, C., Moreau, M., Lestage, J., Castanon, N., Kelley, K. W., & Dantzer, R. (2009) · Molecular Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 1,278

Neuroimmune Interactions: From the Brain to the Immune System and Vice Versa

Dantzer, R. (2018) · Physiological Reviews

Tryptophan and brain disordersVagus Nerve Stimulation Research

Cited by 1,073

Cytokine-induced sickness behaviour: mechanisms and implications

Konsman, J. P., Parnet, P., & Dantzer, R. (2002) · Trends in Neurosciences

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 999

Cytokine-induced sickness behavior: where do we stand?

Dantzer, R. (2001) · Brain, Behavior, and Immunity

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 862

Cytokine, Sickness Behavior, and Depression

Dantzer, R. (2009) · Immunology and Allergy Clinics of North America

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 789

Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity

Dantzer, R. (2004) · European Journal of Pharmacology

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 743

Inflammation-associated depression: From serotonin to kynurenine

Dantzer, R., O’Connor, J. C., Lawson, M. A., & Kelley, K. W. (2011) · Psychoneuroendocrinology

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 726

Cytokine-induced sickness behavior

Kelley, K. W., Bluthé, R.-M., Dantzer, R., Zhou, J.-H., Shen, W.-H., Johnson, R. W., & Broussard, S. R. (2003) · Brain, Behavior, and Immunity

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 716

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions

Kappelmann, N., Lewis, G., Dantzer, R., Jones, P. B., & Khandaker, G. M. (2018) · Molecular Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 659

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

Raison, C. L., Dantzer, R., Kelley, K. W., Lawson, M. A., Woolwine, B. J., Vogt, G., Spivey, J. R., Saito, K., & Miller, A. H. (2010) · Molecular Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 630

Stress and immunity: An integrated view of relationships between the brain and the immune system

Dantzer, R., & Kelley, K. W. (1989) · Life Sciences

Stress Responses and CortisolCancer, Stress, Anesthesia, and Immune Response

Cited by 534

Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice

Layé, S., Parnet, P., Goujon, E., & Dantzer, R. (1994) · Molecular Brain Research

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 500

Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy

Capuron, L., Ravaud, A., Neveu, P. J., Miller, A. H., Maes, M., & Dantzer, R. (2002) · Molecular Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 473

Neuroinflammation and comorbidity of pain and depression

Walker, A. K., Kavelaars, A., Heijnen, C. J., & Dantzer, R. (2014) · Pharmacological Reviews

Tryptophan and brain disordersPain Mechanisms and Treatments

Cited by 460

Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior

Frenois, F., Moreau, M., O’Connor, J., Lawson, M., Micon, C., Lestage, J., Kelley, K. W., Dantzer, R., & Castanon, N. (2007) · Psychoneuroendocrinology

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 438

NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

Walker, A. K., Budac, D. P., Bisulco, S., Lee, A. W., Smith, R. A., Beenders, B., Kelley, K. W., & Dantzer, R. (2013) · Neuropsychopharmacology

Tryptophan and brain disordersTreatment of Major Depression

Cited by 432

Modulation of social memory in male rats by neurohypophyseal peptides

Dantzer, R., Bluthe, R. M., Koob, G. F., & Le Moal, M. (1987) · Psychopharmacology

Neuroendocrine regulation and behaviorMemory and Neural Mechanisms

Cited by 423

Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?

Dantzer, R., Konsman, J.-P., Bluthé, R.-M., & Kelley, K. W. (2000) · Autonomic Neuroscience

Vagus Nerve Stimulation ResearchTryptophan and brain disorders

Cited by 400

The neuroimmune basis of fatigue

Dantzer, R., Heijnen, C. J., Kavelaars, A., Laye, S., & Capuron, L. (2014) · Trends in Neurosciences

Tryptophan and brain disordersFibromyalgia and Chronic Fatigue Syndrome Research

Cited by 346

Cytokine, sickness behavior, and depression

Dantzer, R. (2006) · Neurologic Clinics

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 340

Aging Exacerbates Depressive-like Behavior in Mice in Response to Activation of the Peripheral Innate Immune System

Godbout, J. P., Moreau, M., Lestage, J., Chen, J., Sparkman, N. L., Connor, J. O., Castanon, N., Kelley, K. W., Dantzer, R., & Johnson, R. W. (2008) · Neuropsychopharmacology

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 299

Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder

Savitz, J., Drevets, W. C., Smith, C. M., Victor, T. A., Wurfel, B. E., Bellgowan, P. S., Bodurka, J., Teague, T. K., & Dantzer, R. (2015) · Neuropsychopharmacology

Tryptophan and brain disordersTreatment of Major Depression

Cited by 272