Orkin, Stuart H.

Customizing the genome as therapy for the β-hemoglobinopathies.

Canver, M. C., & Orkin, S. H. (2016) · Blood

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 61

TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network

Seruggia, D., Oti, M., Tripathi, P., Canver, M. C., LeBlanc, L., Di Giammartino, D. C., Bullen, M. J., Nefzger, C. M., Sun, Y. B. Y., Farouni, R., et al. (2019) · Molecular Cell

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 51

14q32 and let-7 microRNAs regulate transcriptional networks in fetal and adult human erythroblasts

Lessard, S., Beaudoin, M., Orkin, S. H., Bauer, D. E., & Lettre, G. (2018) · Human Molecular Genetics

Hemoglobinopathies and Related DisordersMicroRNA in disease regulation

Cited by 38

A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia

Harada, T., Heshmati, Y., Kalfon, J., Ferrucio, J. X., Perez, M., Ewers, J., Kossenkov, A., Ellegast, J. M., Yi, J. S., Bowker, A., et al. (2021) · Genes & Development

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 31

CellMapper: rapid and accurate inference of gene expression in difficult-to-isolate cell types

Nelms, B. D., Waldron, L., Barrera, L. A., Weflen, A. W., Goettel, J. A., Guo, G., Montgomery, R. K., Neutra, M. R., Breault, D. T., Snapper, S. B., et al. (2016) · Genome biology

Gene expression and cancer classificationSingle-cell and spatial transcriptomics

Cited by 24