Wyllie, David J.A.

Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus

Manabe, T., Wyllie, D. J., Perkel, D. J., & Nicoll, R. A. (1993) · Journal of Neurophysiology

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 666

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

Papadia, S., Soriano, F. X., Léveillé, F., Martel, M.-A., Dakin, K. A., Hansen, H. H., Kaindl, A., Sifringer, M., Fowler, J., Stefovska, V., et al. (2008) · Nature Neuroscience

Redox biology and oxidative stressNeuroscience and Neuropharmacology Research

Cited by 498

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

Bilican, B., Serio, A., Barmada, S. J., Nishimura, A. L., Sullivan, G. J., Carrasco, M., Phatnani, H. P., Puddifoot, C. A., Story, D., Fletcher, J., et al. (2012) · Proceedings of the National Academy of Sciences

Amyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells Research

Cited by 328

Influence of GluN2 subunit identity on NMDA receptor function

Wyllie, D. J. A., Livesey, M. R., & Hardingham, G. E. (2013) · Neuropharmacology

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 260

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

Bell, K. F. S., Al-Mubarak, B., Martel, M.-A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., et al. (2015) · Nature Communications

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 191

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

Clayton, E. L., Sue, N., Smillie, K. J., O'Leary, T., Bache, N., Cheung, G., Cole, A. R., Wyllie, D. J., Sutherland, C., Robinson, P. J., et al. (2010) · Nature Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 169

A rise in postsynaptic Ca 2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons

Wyllie, D. J. A., Manabe, T., & Nicoll, R. A. (1994) · Neuron

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 112

Conserved Hippocampal Cellular Pathophysiology but Distinct Behavioural Deficits in a New Rat Model of FXS

Till, S. M., Asiminas, A., Jackson, A. D., Katsanevaki, D., Barnes, S. A., Osterweil, E. K., Bear, M. F., Chattarji, S., Wood, E. R., Wyllie, D. J. A., et al. (2015) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 109

A role for protein kinases and phosphatases in the Ca2+-induced enhancement of hippocampal AMPA receptor-mediated synaptic responses

Wyllie, D. J. A., & Nicoll, R. A. (1994) · Neuron

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 104

SynGAP isoforms exert opposing effects on synaptic strength

McMahon, A. C., Barnett, M. W., O'Leary, T. S., Stoney, P. N., Collins, M. O., Papadia, S., Choudhary, J. S., Komiyama, N. H., Grant, S. G. N., Hardingham, G. E., et al. (2012) · Nature Communications

Neuroscience and Neuropharmacology ResearchRNA Research and Splicing

Cited by 91

Convergence of Hippocampal Pathophysiology in Syngap +/− and Fmr1 −/ y Mice

Barnes, S. A., Wijetunge, L. S., Jackson, A. D., Katsanevaki, D., Osterweil, E. K., Komiyama, N. H., Grant, S. G. N., Bear, M. F., Nägerl, U. V., Kind, P. C., et al. (2015) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 84

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome

Asiminas, A., Jackson, A. D., Louros, S. R., Till, S. M., Spano, T., Dando, O., Bear, M. F., Chattarji, S., Hardingham, G. E., Osterweil, E. K., et al. (2019) · Science Translational Medicine

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 78

Neuronal homeostasis: time for a change?

O’Leary, T., & Wyllie, D. J. A. (2011) · The Journal of Physiology

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 74

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction

Perkins, E. M., Burr, K., Banerjee, P., Mehta, A. R., Dando, O., Selvaraj, B. T., Suminaite, D., Nanda, J., Henstridge, C. M., Gillingwater, T. H., et al. (2021) · Molecular Neurodegeneration

Amyotrophic Lateral Sclerosis ResearchNeuroscience and Neuropharmacology Research

Cited by 54

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

McKay, S., Ryan, T. J., McQueen, J., Indersmitten, T., Marwick, K. F. M., Hasel, P., Kopanitsa, M. V., Baxter, P. S., Martel, M.-A., Kind, P. C., et al. (2018) · Cell Reports

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 42

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons.

Sharma, S. D., Reddy, B. K., Pal, R., Ritakari, T. E., Cooper, J. D., Selvaraj, B. T., Kind, P. C., Chandran, S., Wyllie, D. J. A., & Chattarji, S. (2023) · Cell Reports

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 31

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.

Das Sharma, S., Pal, R., Reddy, B. K., Selvaraj, B. T., Raj, N., Samaga, K. K., Srinivasan, D. J., Ornelas, L., Sareen, D., Livesey, M. R., et al. (2020) · Molecular Autism

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 28

Key roles of C2/GAP domains in SYNGAP1-related pathophysiology

Katsanevaki, D., Till, S. M., Buller-Peralta, I., Nawaz, M. S., Louros, S. R., Kapgal, V., Tiwari, S., Walsh, D., Anstey, N. J., Petrović, N. G., et al. (2024) · Cell Reports

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 22