Barton, Geoffrey J.

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

Schurch, N. J., Schofield, P., Gierliński, M., Cole, C., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G. G., Owen-Hughes, T., et al. (2016) · RNA

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 966

PDBe-KB: collaboratively defining the biological context of structural data

PDBe-KB consortium, Varadi, M., Anyango, S., Armstrong, D., Berrisford, J., Choudhary, P., Deshpande, M., Nadzirin, N., Nair, S. S., Pravda, L., et al. (2022) · Nucleic Acids Research

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 82

Classification of likely functional state for ligand binding sites identified from fragment screening

Utgés, J. S., MacGowan, S. A., Ives, C. M., & Barton, G. J. (2023) · Communications Biology

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 10

Classification of likely functional class for ligand binding sites identified from fragment screening

Utgés, J. S., MacGowan, S. A., Ives, C. M., & Barton, G. J. (2024) · Communications Biology

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 10

A unified analysis of evolutionary and population constraint in protein domains highlights structural features and pathogenic sites

MacGowan, S. A., Madeira, F., Britto-Borges, T., & Barton, G. J. (2024) · Communications Biology

Genomics and Rare DiseasesEvolution and Genetic Dynamics

Cited by 8

A unified approach to evolutionary conservation and population constraint in protein domains highlights structural features and pathogenic sites

MacGowan, S. A., Madeira, F., Britto-Borges, T., & Barton, G. J. (2023) · Communications Biology

Genomics and Rare DiseasesEvolution and Genetic Dynamics

Cited by 8

Mutations within the predicted fragment-binding region of FAM83G/SACK1G abolish its interaction with the Ser/Thr kinase CK1α

Utgés, J. S., Xuan, D. L. Z., Le Chatelier, B., Glennie, L., Macartney, T. J., Wood, N. T., Barton, G. J., & Sapkota, G. P. (2025) · Open Biology

Wnt/β-catenin signaling in development and cancerProtein Structure and Dynamics

Cited by 0